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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Knoz-200 Capsule 10's is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It contains Itraconazole, which works by killing fungi. Some people may experience side effects such as nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Laxian Healthcare

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Knoz-200 Capsule 10's

Knoz-200 Capsule 10's is an antifungal medicine used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Knoz-200 Capsule 10's contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.

Take Knoz-200 Capsule 10's as prescribed. Your doctor will advise you on how often you take Knoz-200 Capsule 10's based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Knoz-200 Capsule 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Knoz-200 Capsule 10's or any other medicines, please tell your doctor. Knoz-200 Capsule 10's is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Knoz-200 Capsule 10's. Do not take Knoz-200 Capsule 10's if you have or have heart failure, as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Knoz-200 Capsule 10's. Avoid taking fentanyl (a strong opioid narcotic medicine) with Knoz-200 Capsule 10's as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Knoz-200 Capsule 10's and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Knoz-200 Capsule 10's

Treatment of Fungal infections

Medicinal Benefits

Knoz-200 Capsule 10's is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Knoz-200 Capsule 10's inhibits the production of ergosterol (a main component of cell membranes of fungi). Thereby weakening and damaging the fungal cell membranes, causing the main components of fungal cells to leak out. Thus, it kills fungi and clears the fungal infection.

Directions for Use

Tablet: Take it with food to avoid stomach upset or as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it. If you are taking any stomach acid suppressor or have achlorhydria (stomach does not produce hydrochloric acid), take Knoz-200 Capsule 10's with cola.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Knoz-200 Capsule 10's

  • Nausea
  • Headache
  • Diarrhoea
  • Tiredness
  • Cough
  • Cold
  • Throat pain
  • Back pain
  • Stomach pain

Drug Warnings

If you are known to be allergic to Knoz-200 Capsule 10's or any other medicines, please tell your doctor. Knoz-200 Capsule 10's is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Knoz-200 Capsule 10's. Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Knoz-200 Capsule 10's, as it may cause severe breathing problems and can even lead to death. Do not take Knoz-200 Capsule 10's if you had heart failure as it may cause severe life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Knoz-200 Capsule 10's and consult a doctor immediately as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Knoz-200 Capsule 10's.

Drug Interactions

Drug-Drug Interaction: Knoz-200 Capsule 10's may interact with antacids (esomeprazole, omeprazole, pantoprazole), corticosteroids (fluticasone, budesonide), opioid pain killers (hydrocodone), blood thinners (warfarin), blood cholesterol-lowering medicines (simvastatin), anti-allergic drug (terfenadine) and antianxiety drug (alprazolam).

Drug-Food Interaction: Knoz-200 Capsule 10's may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with Knoz-200 Capsule 10's as it may reduce the effect of Knoz-200 Capsule 10's. Also, avoid intake of marijuana with Knoz-200 Capsule 10's as it may worsen the adverse effects of marijuana.

Drug-Disease Interaction: Do not take Knoz-200 Capsule 10's if you had heart failure as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Knoz-200 Capsule 10's.

Drug-Drug Interactions Checker List

  • ESOMEPRAZOLE
  • OMEPRAZOLE
  • PANTOPRAZOLE
  • FLUTICASONE
  • BUDESONIDE
  • HYDROCODONE
  • WARFARIN
  • SIMVASTATIN
  • TERFENADINE
  • ALPRAZOLAM

Habit Forming

No

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
  • Do not scratch the affected area of skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Special Advise

  • Regular blood tests are recommended before and while taking Knoz-200 Capsule 10's to monitor liver functioning especially if you have any liver problems.

Disease/Condition Glossary

Fungal infection: It is a skin disease in which a fungus attacks the tissue and causes infection. It may be contagious (spread from one person to another). The symptoms of a fungal infection include blisters, itching, redness, scaling and swelling of the skin. Yeast infection is caused by a type of fungus called candida and commonly occurs in moist and warm areas of the body. It is not contagious. It may cause infections in the mouth (oral thrush), vagina, nails, groin or armpits.

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Alcohol

Unsafe

Avoid consumption of alcohol with Knoz-200 Capsule 10's as it may increase the risk of liver problems and other adverse effects.

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Pregnancy

Unsafe

Knoz-200 Capsule 10's is category C pregnancy drug and is unsafe for pregnant women as it may cause harm to the unborn baby. Therefore, inform your doctor if you are pregnant or planning for pregnancy before taking Knoz-200 Capsule 10's.

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Breast Feeding

Caution

Knoz-200 Capsule 10's is excreted in human milk and may harm the baby. Therefore, Knoz-200 Capsule 10's is given to breastfeeding mothers only if doctor thinks benefits are greater than risks.

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Driving

Caution

Knoz-200 Capsule 10's may cause dizziness, hearing loss, double or blurred vision in some people. Therefore, drive only if you alert after taking Knoz-200 Capsule 10's.

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Liver

Caution

Take Knoz-200 Capsule 10's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Knoz-200 Capsule 10's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Knoz-200 Capsule 10's is not recommended for children below 12 years as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

Goregaon (West), Mumbai Maharastra, Pin Code - 400104
Other Info - KNO0053

Author Details

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FAQs

Knoz-200 Capsule 10's is used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. It works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby killing fungi and clearing the fungal infection.
You are not recommended to take Knoz-200 Capsule 10's with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Knoz-200 Capsule 10's with other medicines.
No, Knoz-200 Capsule 10's is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Knoz-200 Capsule 10's and after 2 months of stopping treatment with Knoz-200 Capsule 10's. However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Knoz-200 Capsule 10's.
Knoz-200 Capsule 10's may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Knoz-200 Capsule 10's to experience this adverse effect. However, if you notice any changes in hearing, stop taking Knoz-200 Capsule 10's and consult a doctor immediately.
You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Knoz-200 Capsule 10's as co-administration of these medicines at the same time may reduce the effectiveness of Knoz-200 Capsule 10's because antacids decrease the absorption and blood levels of Knoz-200 Capsule 10's. However, please consult a doctor before taking other medicines with Knoz-200 Capsule 10's.
Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.
You are not recommended to stop taking Knoz-200 Capsule 10's without consulting your doctor as it may cause recurring infection. Therefore, take Knoz-200 Capsule 10's for as long as your doctor has prescribed it, and if you experience any difficulty while taking Knoz-200 Capsule 10's, please consult your doctor.
Inform your doctor if you are sexually active and discuss effective contraception methods. Knoz-200 Capsule 10's may reduce the effectiveness of oral contraceptive pills. Thus, you are advised to use barrier methods of contraception like condoms, if you are taking Knoz-200 Capsule 10's.
Inform the doctor about your detailed medical and surgical history, if you have liver, kidney or heart disease or fits and if you are pregnant, breastfeeding or planning pregnancy. Inform your doctor if you are taking any other medicines including supplements or herbal products as Knoz-200 Capsule 10's may interact with other medicines. Also, let your doctor know if you are stopping any medicine.
Knoz-200 Capsule 10's contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, it causes the main components of fungal cells to leak out, kill fungi, and clear the fungal infection.
Yes, you should swallow the capsule whole with a glass of water. Do not crush, chew or break it.
The side effects of Knoz-200 Capsule 10's include nausea, headache, diarrhoea, stomach pain, fatigue (overtiredness), back pain, cough, and sore throat. If these side effects persist or worsen, please consult your doctor.
If you have taken overdose of Knoz-200 Capsule 10's, please consult your doctor immediately.
Store Knoz-200 Capsule 10's at room temperature. Protect from light and moisture. Keep out of reach and sight of children.

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