Gestomine-400 Softgel Capsule is used in combination with oestrogen for hormone replacement therapy. Besides this, Gestomine-400 Softgel Capsule also treats amenorrhoea (absence of menstrual periods) and prevents endometrial hyperplasia (thickened uterus lining). Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour. Hormone replacement therapy is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

Gestomine-400 Softgel Capsule contains progesterone, which works by replacing oestrogen and progesterone hormone levels in the body and providing relief from menopause symptoms.

You are advised to take Gestomine-400 Softgel Capsule for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, drowsiness, headache, mood changes, diarrhoea, vaginal discharge, joint pain, hot flashes (sudden feeling of warmth) or constipation. Most of these side effects of Gestomine-400 Softgel Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to soya, Gestomine-400 Softgel Capsule or any other medicines, please tell your doctor. Avoid taking Gestomine-400 Softgel Capsule if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage (bleeding in the brain). Avoid taking Gestomine-400 Softgel Capsule if you are pregnant, as it may harm the unborn baby. You are advised to use effective birth control methods while taking Gestomine-400 Softgel Capsule to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Gestomine-400 Softgel Capsule . Drive only if you are alert, as Gestomine-400 Softgel Capsule may cause drowsiness or dizziness.

Gestomine-400 Softgel Capsule contains Progesterone that is used in combination with oestrogen for hormone replacement therapy. Also, Gestomine-400 Softgel Capsule is used to treat amenorrhoea (absence of menstrual periods due to lack of progesterone) and prevent endometrial hyperplasia (unusually thick lining of the uterus). Gestomine-400 Softgel Capsule replaces oestrogen and progesterone hormone levels in the body and helps in providing relief from menopause symptoms. Also, it is indicated for the maintenance of pregnancy, threatened abortion and prevention of preterm labour.

• Dizziness
• Drowsiness
• Headache
• Mood changes
• Diarrhoea
• Vaginal discharge
• Joint pain
• Hot flashes (sudden feeling of warmth) 
• Constipation

If you are allergic to soya, Gestomine-400 Softgel Capsule or any other medicines, please tell your doctor. Avoid taking Gestomine-400 Softgel Capsule if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment) or cerebral haemorrhage  (bleeding in the brain). Avoid taking Gestomine-400 Softgel Capsule if you are pregnant as it may harm the unborn baby. You are advised to use effective birth control methods while taking Gestomine-400 Softgel Capsule to prevent pregnancy. However, if you are pregnant, planning for pregnancy or breastfeeding, please consult a doctor before taking Gestomine-400 Softgel Capsule . Drive only if you are alert as Gestomine-400 Softgel Capsule may cause drowsiness or dizziness. If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease) or if you ever had depression, inform your doctor before taking Gestomine-400 Softgel Capsule . If you are about to undergo any surgery, please inform your doctor that you are taking Gestomine-400 Softgel Capsule .

Drug-Drug Interaction: Gestomine-400 Softgel Capsule may interact with anticonvulsants (carbamazepine, phenytoin, phenobarbital), anti-tuberculosis drugs (rifabutin, rifampicin), anti-HIV drugs (ritonavir, nevirapine, nelfinavir, efavirenz), benzodiazepine (diazepam), water tablet (spironolactone), immunosuppressant (ciclosporin), blood thinners (phenindione), skeletal muscle relaxants (tizanidine), antifungals (terbinafine, ketoconazole, griseofulvin).

Drug-Food Interaction: Gestomine-400 Softgel Capsule may interact with St. Jonh’s wort (herbal supplement to treat depression).

Drug-Disease Interaction: Avoid taking Gestomine-400 Softgel Capsule if you have breast cancer, unexplained vaginal bleeding, blood clots or blood clotting disorder, liver disease, porphyria (a disorder in the formation of red blood pigment), or cerebral hemorrhage  (bleeding in the brain). If you have diabetes, high blood pressure, migraine or severe headaches, gallstones, asthma, fits, systemic lupus erythematosus (an autoimmune disease), or if you ever had depression, inform your doctor before taking Gestomine-400 Softgel Capsule .

• CARBAMAZEPINE
• PHENYTOIN
• PHENOBARBITAL
• RIFABUTIN
• RIFAMPICIN
• RITONAVIR
• NEVIRAPINE
• NELFINAVIR
• EFAVIRENZ
• DIAZEPAM
• SPIRONOLACTONE
• CICLOSPORIN
• PHENINDIONE
• TIZANIDINE
• TERBINAFINE
• KETOCONAZOLE
• GRISEOFULVIN

• Do regular exercise and physical activity to minimize hot flushes and improve sleep. Aerobics, yoga, and activities like tai chi may help in relaxing the body and mind.

• Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flushes and night sweats. Take minimum sleep of 8 hours.

• Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.

• Try to be stress-free to improve your mood swings due to hormonal fluctuations.

• Quit smoking as it will help to reduce hot flushes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

If you need to undergo any blood test, please inform the lab technician that you are taking hormone replacement therapy (HRT) as it may affect some test results.

Hormone replacement therapy (HRT): It is a treatment to relieve menopause symptoms. It replaces hormones that are at a lower level as you approach menopause.

Amenorrhoea: It is the absence of menstrual periods in a woman of childbearing potential due to a lack of progesterone.

Endometrial hyperplasia: It is a condition where the uterus lining (endometrium) becomes unusually thick due to excessive cells (hyperplasia).