apollo
logo
0Login
Introducing Our Latest Arrival!
Enpex 100mg/250mg Tablet

Enpex 100mg/250mg Tablet

Prescription drug
 Trailing icon
Consult Doctor

Manufacturer/Marketer

Ester Formulations

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Enpex 100mg/250mg Tablet

Enpex 100mg/250mg Tablet belongs to the group of medicines called muscle relaxants indicated for the relief of painful skeletal muscle spasms. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasms are the involuntary contractions of muscles which can be painful. Musculoskeletal pain affects the bones, muscles, ligaments, tendons and nerves.

Enpex 100mg/250mg Tablet is a combination of two drugs: Nimesulide (NSAID) and Chlorzoxazone (Muscle relaxant). Nimesulide works by inhibiting the synthesis of prostaglandins which are responsible for pain and inflammation. Chlorzoxazone acts on the brain and spinal cord centres where it inhibits multisynaptic reflex involved in muscle spasms, thereby providing relief from skeletal muscle spasms or stiffness. Together, Enpex 100mg/250mg Tablet helps in relieving musculoskeletal pain.

You are advised to take Enpex 100mg/250mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, Enpex 100mg/250mg Tablet may cause common side-effects such as nausea, vomiting, diarrhoea, weakness, and stomach upset. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Enpex 100mg/250mg Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Enpex 100mg/250mg Tablet as it could increase the risk of stomach bleeding. Enpex 100mg/250mg Tablet may cause sleepiness and dizziness, so drive only if you are alert. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of Enpex 100mg/250mg Tablet

Treatment of Musculoskeletal pain.

Medicinal Benefits

Enpex 100mg/250mg Tablet is a combination of two drugs, namely: Nimesulide and Chlorzoxazone. Enpex 100mg/250mg Tablet is used to relieve pain and stiffness caused by muscle strains and sprains. Nimesulide is an NSAID that inhibits the synthesis of prostaglandins responsible for pain and inflammation. Chlorzoxazone is a muscle relaxant that acts on the brain and spinal cord centres, where it inhibits the multisynaptic reflex involved in muscle spasms, thereby providing relief from skeletal muscle spasms or stiffness. Together, Enpex 100mg/250mg Tablet helps in relieving pain due to muscle spasms.

Directions for Use

Take Enpex 100mg/250mg Tablet with food to prevent stomach upset. Swallow Enpex 100mg/250mg Tablet as a whole with a glass of water, do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Enpex 100mg/250mg Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Weakness
  • Stomach upset
  • Heart burn or abdominal cramps

Drug Warnings

Do not take Enpex 100mg/250mg Tablet if you are allergic to any of its contents, if you have bronchospasm, asthma or breathing problems, gastrointestinal bleeding or perforation, coagulation or bleeding problems and severe heart problems. Inform your doctor if you have heart, kidney or liver impairment. Consult your doctor if you are pregnant or breastfeeding. Enpex 100mg/250mg Tablet is not recommended for children as safety has not been established. Avoid consuming alcohol with Enpex 100mg/250mg Tablet as it could increase the risk of stomach bleeding. Enpex 100mg/250mg Tablet may cause sleepiness and dizziness, so drive only if you are alert. Stop taking Enpex 100mg/250mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Enpex 100mg/250mg Tablet unless prescribed.

Drug Interactions

Drug-Drug Interactions: Enpex 100mg/250mg Tablet may interact with blood thinners (warfarin), hypnotics (zolpidem), anti-depressant (duloxetine, escitalopram), antihistamines (diphenhydramine, cetirizine), anti-convulsant (pregabalin, topiramate), anti-hypertensive (metoprolol), pain killers (acetaminophen, hydrocodone), anti-anxiety (alprazolam), anti-psychotic (lithium), diuretic (furosemide), other muscle relaxants ( carisoprodol, cyclobenzaprine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have bronchospasm, asthma or breathing problems, gastrointestinal bleeding or perforation, coagulation or bleeding problems, heart, kidney, or liver dysfunction.

Drug-Drug Interactions Checker List

  • WARFARIN
  • ZOLPIDEM
  • DULOXETINE
  • ESCITALOPRAM
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • PREGABALIN
  • TOPIRAMATE
  • METOPROLOL
  • HYDROCODONE
  • ACETAMINOPHEN
  • ALPRAZOLAM
  • LITHIUM
  • FUROSEMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Special Advise

  • Enpex 100mg/250mg Tablet may rarely cause your urine to turn orange or reddish-purple. This effect is harmless and will disappear when the medication is stopped.
  • If you experience bloody or tarry stools, stop using Enpex 100mg/250mg Tablet and consult a doctor.

Disease/Condition Glossary

Musculoskeletal pain: Musculoskeletal pain affects the bones, muscles, ligaments, tendons and nerves. It can be acute or chronic and can be localised or widespread. The pain can be mild or severe enough to interfere with your daily routine. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure or injury to the bones, joints, tendons, muscles and ligaments. Symptoms of musculoskeletal pain include stiffness, swelling, redness, weakness, muscle spasms or twitching, trouble moving the affected area, soreness, and cracking or popping sound at the joints.

bannner image

Alcohol

Unsafe

Avoid consumption of alcohol while taking Enpex 100mg/250mg Tablet as it may increase the risk of stomach bleeding.

bannner image

Pregnancy

Caution

Please consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Please consult your doctor if you are breastfeeding; your doctor will decide whether Enpex 100mg/250mg Tablet can be taken by breastfeeding mothers or not.

bannner image

Driving

Caution

Enpex 100mg/250mg Tablet may cause dizziness. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Caution

Enpex 100mg/250mg Tablet is not recommended in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Enpex 100mg/250mg Tablet should not be given to children as the safety and effectiveness were not established.

Country of origin

India
Other Info - EN44846

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Enpex 100mg/250mg Tablet is used for the relief of painful skeletal muscle spasms.
Enpex 100mg/250mg Tablet contains Nimesulide and Chlorzoxazone. Nimesulide works by inhibiting the synthesis of prostaglandins responsible for pain and inflammation. Chlorzoxazone acts on the brain and spinal cord centres, where it inhibits the multisynaptic reflex involved in muscle spasms, thereby providing relief from skeletal muscle spasms. Together, Enpex 100mg/250mg Tablet helps in relieving musculoskeletal pain.
Enpex 100mg/250mg Tablet is generally prescribed for short-term use. Avoid taking Enpex 100mg/250mg Tablet for longer durations unless prescribed by the doctor, as it could lead to unpleasant side effects and liver damage. Use the minimum effective dose for the shortest duration of time.
Do not take Enpex 100mg/250mg Tablet along with other painkiller medicines unless prescribed by the doctor, as it can lead to unpleasant side effects and can increase the risk of stomach bleeding associated with NSAIDs.
Physical therapy helps relieve muscle spasms. Therefore, proper rest and physical therapy are recommended to enhance and complement treatment with Enpex 100mg/250mg Tablet.
Diarrhoea might be a side-effect of Enpex 100mg/250mg Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in stools.
Enpex 100mg/250mg Tablet contains Nimesulide, an NSAID, which can enhance the activity of anticoagulant drugs leading to an increased risk of bleeding complications. Therefore, it is not recommended to take anti-coagulants along with Enpex 100mg/250mg Tablet unless told by the doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.