apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:20 PM IST

Dothichem-50 Tablet 10's is used to treat depression that is unresponsive to other antidepressants or any other alternative treatment. It is also used to treat disorders related to anxiety. It contains Dosulepin, which works by increasing the levels of chemical messengers which are responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. It provides relief from symptoms such as feelings of restlessness, irritability, tiredness, difficulty concentrating, feeling, and sleep disturbances. It helps to carry out daily activities easily. In some cases, you may experience increased heart rate, blurred vision, dizziness, dryness in the mouth and constipation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

Read more
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Synonym

DOSULEPIN HYDROCHLORIDE

Composition

DOSULEPIN-50MG

Manufacturer/Marketer

Lupichem Healthcare

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Dothichem-50 Tablet 10's

Dothichem-50 Tablet 10's belongs to the class of tricyclic antidepressants. It is primarily used to treat depression that is unresponsive to other antidepressants or any other alternative treatment. It is also used to treat disorders related to anxiety. Depression is a mood disorder that affects day to day life of a person. A person may have symptoms such as feeling sad or feeling of loss and might have mood swings. Anxiety is defined as an emotion that is characterized by feelings of tension, worried thoughts, and symptoms like increased blood pressure. Anxiety disorder also includes panic disorder which is characterized by sudden feelings of terror.

Dothichem-50 Tablet 10's works by increasing the levels of chemical messengers which are responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. It provides relief from symptoms such as feelings of restlessness, irritability, tiredness, difficulty concentrating, feeling, and sleep disturbances. It helps to carry out daily activities easily.

Dothichem-50 Tablet 10's should be taken in dose and duration as advised by the doctor and taking it before bedtime should be preferred as it can make you feel drowsy. It can be taken with or without food, but it should be taken at a fixed time each day. In some cases, you may experience increased heart rate, blurred vision, dizziness, dryness in the mouth and constipation. Most of these side effects of Dothichem-50 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine on your own without consulting your doctor as it may lead to withdrawal symptoms. Do not take this medicine if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty in sleeping (sleep apnoea), severe liver disease or problem with alcohol or other prescription recreational drugs. Inform your doctor if you are planning to get pregnant, are pregnant, or breastfeeding. Also, tell your doctor if you are allergic to this medicine.

Uses of Dothichem-50 Tablet 10's

Treatment of Depression, Anxiety

Medicinal Benefits

Dothichem-50 Tablet 10's works by increasing the levels of chemical messengers which are responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. Dothichem-50 Tablet 10's provides relief from symptoms such as feelings of restlessness, irritability, tiredness, difficulty concentrating, feeling, and sleep disturbances. It helps to carry out daily activities easily.

Directions for Use

Dothichem-50 Tablet 10's should not be used unless prescribed by a doctor. Always take Dothichem-50 Tablet 10's exactly as your doctor told you. Your doctor will advise you on how often you take your tablets on the basis of your medical condition. Swallow Dothichem-50 Tablet 10's with a full glass of water.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dothichem-50 Tablet 10's

  •  Increased heart rate
  • Blurred vision
  • Dizziness
  • Dryness in the mouth
  • Weight gain
  • Sudden lowering of blood pressure on standing
  • Difficulty in urination
  • Constipation

Drug Warnings

Dothichem-50 Tablet 10's should be given with extreme caution in patients having epilepsy (Brain disorder in which brain activity becomes abnormal, causing seizures), impaired liver or kidney function, diabetes, decreased level of sodium in the blood, tendency to easily develop bleedings or bruises, patients receiving electroconvulsive treatment, having coronary heart disease, suffering or have suffered from heart problems or have recently had a heart attack, having a low resting heart-rate, having prolonged severe diarrhoea and vomiting (Being sick) or using diuretics (water tablets), experiencing a fast or irregular heartbeat, fainting, collapse, or dizziness on standing up, which may indicate abnormal functioning of the heart rate and having or previously had eye problems, such as certain kinds of glaucoma (increased pressure in the eye).

Drug Interactions

Drug-Drug Interaction: This medicine may have an interaction with other anti-depressants such as phenelzine, iproniazid, isocarboxazid, nialamide, imipramine, and desipramine and tranylcypromine, moclobemide, medicines used to treat Parkinson's disease such as selegiline. Taking this medicine with Dothichem-50 Tablet 10's can increase the risk of side effects. It can also have an interaction with antibiotic linezolid, lithium (used in the treatment of manic-depressive disorder), and tryptophan, medicines used to treat migraines such as Sumatriptan, medicines used for severe pain such as tramadol, medicines used for stomach ulcers such as Cimetidine, lansoprazole, and omeprazole, medicines used to treat fungal infections such as fluconazole, medicines used to reduce the risk of strokes such as ticlopidine, St. John's Wort (Hypericum perforatum) - a herbal remedy used for depression, blood-thinning medicines (warfarin, dipyridamole, and phenprocoumon) and pain killers, antimalarials such as Mefloquine, medicines used for heart diseases such as Flecainide, propafenone, medicines that decrease blood levels of potassium or magnesium, as these increase the risk of life-threatening heart rhythm disorder

Drug-Food Interaction: Dothichem-50 Tablet 10's may interact with multi-mineral or other herbal/ayurvedic supplements. So, if you are using any of the OTC items please tell your doctor.

Drug-Disease Interaction: Obese people (with a BMI greater than 25) should consult a doctor before taking Dothichem-50 Tablet 10's.

Drug-Drug Interactions Checker List

  • PHENELZINE
  • IPRONIAZID
  • ISOCARBOXAZID
  • NIALAMIDE
  • IMIPRAMINE
  • DESIPRAMINE
  • TRANYLCYPROMINE
  • MOCLOBEMIDE
  • SELEGILINE
  • LINEZOLID
  • LITHIUM
  • TRYPTOPHAN
  • SUMATRIPTAN
  • TRAMADOL
  • CIMETIDINE
  • LANSOPRAZOLE
  • OMEPRAZOLE
  • FLUCONAZOLE
  • TICLOPIDINE
  • WARFARIN
  • DIPYRIDAMOLE
  • PHENPROCOUMON
  • MEFLOQUINE
  • FLECAINIDE
  • PROPAFENONE

Habit Forming

No

Diet & Lifestyle Advise

  • Option for healthy food which in turn will help you to elevate your moods.
  • Exercise daily for at least 30 minutes a day. It will help you to reduce stress and improve your mood. It will also improve your quality of sleep.
  • Take deep breaths to calm your mind.
  • Follow a consistent sleep schedule (at least 8 hours a day).
  • Manage your stress levels by doing activities that make you happy such as watching your favourite show, reading a book, listening to music, and activities of your interest.

Special Advise

Do not stop taking dosulepin without talking to your doctor. You may suffer side effects if you stop taking it suddenly. If you and your doctor agree that you should stop taking dosulepin, your doctor will probably recommend reducing your dose gradually over several weeks.

Disease/Condition Glossary

Depression: It is a mood disorder that affects day to day life of a person. A person may have symptoms such as feeling sad or feeling of loss and might have mood swings.

Anxiety: It is defined as an emotion that is characterized by feelings of tension, worried thoughts, and symptoms like increased blood pressure. Anxiety disorder also includes panic disorder which is characterized by sudden feelings of terror.

bannner image

Alcohol

Unsafe

It is not recommended to take alcohol while taking Dothichem-50 Tablet 10's to avoid unpleasant side-effects.

bannner image

Pregnancy

Unsafe

It is advised not to take Dothichem-50 Tablet 10's during pregnancy as it may pose risk to the unborn baby. However, if you are already taking Dothichem-50 Tablet 10's, please inform your doctor that you are pregnant.

bannner image

Breast Feeding

Safe if prescribed

Dothichem-50 Tablet 10's passes in very small amounts in breast milk. It has not been linked with any side-effects. However, caution is advised while taking it. Please inform your doctor if you are breastfeeding.

bannner image

Driving

Unsafe

It is not recommended to drive after taking Dothichem-50 Tablet 10's as it can make you feel drowsy.

bannner image

Liver

Caution

Caution is advised while taking Dothichem-50 Tablet 10's if you suffer or have suffered from liver diseases.

bannner image

Kidney

Caution

Caution is advised while taking Dothichem-50 Tablet 10's if you suffer or have suffered from kidney diseases.

bannner image

Children

Unsafe

Dothichem-50 Tablet 10's is not recommended in children below 12 years of age.

Country of origin

India

Manufacturer/Marketer address

311, Shreyas Complex, Vejalpur Bus-Stand, Nr, Prahlad Nagar Main ROad, Ahmedabad-51
Other Info - DOT0129

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Dothichem-50 Tablet 10's is used to treat depression and anxiety. It works by increasing the levels of chemical messengers which are responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety.
Dothichem-50 Tablet 10's helps to elevate your mood levels. After taking it, you easily communicate with other people. It helps you to get better sleep. It helps you to feel like yourself again.
It depends on your symptoms according to which your doctor will advise the dose and duration of Dothichem-50 Tablet 10's. Please inform your doctor if you are planning to switch to any other antidepressant.
Dothichem-50 Tablet 10's is not recommended to treat pain. Rarely, it is advised to treat nerve pain like fibromyalgia or to prevent migraine.
No, Dothichem-50 Tablet 10's is not a habit-forming drug. However, it can cause side-effects especially when you stop taking it suddenly.
Dothichem-50 Tablet 10's might cause weight gain as taking it makes you feel hungry. However, it varies from person to person as some people might feel less hungry after taking it.
Dothichem-50 Tablet 10's starts to show its full effect in 4 to 6 weeks. In case, you feel that you are not feeling better or there is no improvement in the symptoms, please consult your doctor. In case, you feel that you are experiencing any kind of side-effect after taking Dothichem-50 Tablet 10's, please contact your doctor immediately.
Dothichem-50 Tablet 10's may interact with several medications and impact their efficacy. So, taking any medications, including herbal or ayurvedic, other than those prescribed by the doctor is not recommended.
No, it is not a muscle relaxant. Dothichem-50 Tablet 10's is a tricyclic antidepressant medication used to treat depression.
Both Dothichem-50 Tablet 10's and amitriptyline belong to the tricyclic antidepressant class used to treat symptoms of depression. However, do not replace the Dothichem-50 Tablet 10's with amitriptyline unless recommended by the doctor.
Dothichem-50 Tablet 10's and doxepin belong to tricyclic antidepressant class medications used to treat symptoms of depression. However, they may have different mechanisms of action. However, do not replace the Dothichem-50 Tablet 10's with doxepin unless recommended by the doctor.
You may take several weeks or longer to experience the full effect of Dothichem-50 Tablet 10's. Even if you are feeling good, continue to take Dothichem-50 Tablet 10's. Do not discontinue taking Dothichem-50 Tablet 10's without consulting your doctor. Before quitting, your doctor will most likely recommend that you gradually reduce your dose.
Dothichem-50 Tablet 10's is associated with high mortality (death rate) in overdose. There is a low margin of safety between the maximum therapeutic dose and potentially fatal doses. So, you should strictly follow the dose and duration of Dothichem-50 Tablet 10's as directed by the physician. Do not overdose at any cost. If you feel you or someone overdosed or experience any severe adverse events with Dothichem-50 Tablet 10's, consult the doctor or go to the emergency room nearest hospital.
Caution should be exercised. The risk or severity of CNS depression can be increased when Diazepam is combined with Dothichem-50 Tablet 10's.
No. Dothichem-50 Tablet 10's is not intended to treat trigeminal neuralgia (sudden, severe facial pain. It's commonly described as a sudden shooting pain or as an electric shock to the jaw, teeth, or gums.).
No. $ name is not intended to treat burning mouth syndrome (a painful condition often described as a burning, scalding, or tingling feeling in the mouth that may occur every day for months).
Yes, Dothichem-50 Tablet 10's is intended to treat depression. However, it is a prescription medication and should be taken only if the doctor prescribes it to you.
No. Dothichem-50 Tablet 10's is not intended to treat IBS (irritable bowel syndrome). Dothichem-50 Tablet 10's is a tricyclic antidepressant medication used to treat depression.
It is not intended for insomnia with depression alone. However, your doctor may suggest Dothichem-50 Tablet 10's to treat insomnia with depression in some cases. Please consult your doctor for personalized guidance.
Dothichem-50 Tablet 10's can change the way your nerves receive pain signals. This can help with some kinds of nerve pain, including fibromyalgia. However, it should only be taken as prescribed by the doctor.
Dothichem-50 Tablet 10's is sometimes used to treat some types of nerve pain, such as fibromyalgia, or to prevent migraine. But it's not recommended or officially approved for pain relief.
Dothichem-50 Tablet 10's works by increasing levels of a chemical called serotonin in the brain. This can improve your mood.
For depression, it usually takes 4 to 6 weeks for Dothichem-50 Tablet 10's to work fully. However, it varies from person to person.
Dothichem-50 Tablet 10's helps to lift your mood, so you feel better. You may notice that you sleep better and are feeling less anxious. Dothichem-50 Tablet 10's will not change your personality. It'll simply help you feel like yourself again.
No, Dothichem-50 Tablet 10's is not recommended for everyone. It can be harmful to some people and is very dangerous if you take too much. Take personalized guidance from your doctor by letting them know your medical condition and the medications you are taking.
Dothichem-50 Tablet 10's is not addictive, but you may get withdrawal symptoms when you stop taking it, especially if you stop taking it suddenly. Withdrawal symptoms of Dothichem-50 Tablet 10's may include giddiness, headache, insomnia, irritability, increased sweating, nausea, panic-anxiety and restlessness.
Some people feel sleepy while they're taking Dothichem-50 Tablet 10's. If this happens to you, do not drive, cycle or use machinery or tools until you feel better.
It is recommended not to take alcohol while taking Dothichem-50 Tablet 10's. It may make you feel drowsy or may impact how Dothichem-50 Tablet 10's works. So, it would be best to stop drinking alcohol while on treatment.
Limited research is available on Dothichem-50 Tablet 10's in pregnant women. So, talk to your doctor if you are taking Dothichem-50 Tablet 10's and are planning a pregnancy or becoming pregnant. The doctor will help you weigh the risks and benefits to decide on the best treatment for you and your baby. Your mental health must be well treated during pregnancy, as it can affect you and your baby's wellbeing.
No clear evidence suggests that taking Dothichem-50 Tablet 10's will reduce fertility in either men or women. However, speak to a healthcare professional before taking it about its potential benefits and risks.
No, Dothichem-50 Tablet 10's is not recommended for children below 12 years of age. Please seek medical attention if you observe any depression symptoms in your kid.
Symptoms of overdose may include cold body temperature, coma (loss of consciousness for a period of time), feeling agitated, confused, or drowsy, fever, hallucination (seeing things or hearing voices that do not exist), irregular heartbeat, increase in pupil size, muscle stiffness, seizures, trouble concentrating and vomiting.
Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.