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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:20 PM IST

Dolepin 50 Tablet is used to treat depression that is unresponsive to other antidepressants or any other alternative treatment. It is also used to treat disorders related to anxiety. It contains Dosulepin, which works by increasing the levels of chemical messengers which are responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. It provides relief from symptoms such as feelings of restlessness, irritability, tiredness, difficulty concentrating, feeling, and sleep disturbances. It helps to carry out daily activities easily. In some cases, you may experience increased heart rate, blurred vision, dizziness, dryness in the mouth and constipation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Prescription drug

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Synonym

DOSULEPIN HYDROCHLORIDE

Composition

DOSULEPIN-50MG

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Dolepin 50 Tablet

Dolepin 50 Tablet belongs to the class of tricyclic antidepressants. It is primarily used to treat depression that is unresponsive to other antidepressants or any other alternative treatment. It is also used to treat disorders related to anxiety. Depression is a mood disorder that affects day to day life of a person. A person may have symptoms such as feeling sad or feeling of loss and might have mood swings. Anxiety is defined as an emotion that is characterized by feelings of tension, worried thoughts, and symptoms like increased blood pressure. Anxiety disorder also includes panic disorder which is characterized by sudden feelings of terror.

Dolepin 50 Tablet works by increasing the levels of chemical messengers which are responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. It provides relief from symptoms such as feelings of restlessness, irritability, tiredness, difficulty concentrating, feeling, and sleep disturbances. It helps to carry out daily activities easily.

Dolepin 50 Tablet should be taken in dose and duration as advised by the doctor and taking it before bedtime should be preferred as it can make you feel drowsy. It can be taken with or without food, but it should be taken at a fixed time each day. In some cases, you may experience increased heart rate, blurred vision, dizziness, dryness in the mouth and constipation. Most of these side effects of Dolepin 50 Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine on your own without consulting your doctor as it may lead to withdrawal symptoms. Do not take this medicine if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty in sleeping (sleep apnoea), severe liver disease or problem with alcohol or other prescription recreational drugs. Inform your doctor if you are planning to get pregnant, are pregnant, or breastfeeding. Also, tell your doctor if you are allergic to this medicine.

Uses of Dolepin 50 Tablet

Treatment of Depression, Anxiety

Medicinal Benefits

Dolepin 50 Tablet works by increasing the levels of chemical messengers which are responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety. Dolepin 50 Tablet provides relief from symptoms such as feelings of restlessness, irritability, tiredness, difficulty concentrating, feeling, and sleep disturbances. It helps to carry out daily activities easily.

Directions for Use

Dolepin 50 Tablet should not be used unless prescribed by a doctor. Always take Dolepin 50 Tablet exactly as your doctor told you. Your doctor will advise you on how often you take your tablets on the basis of your medical condition. Swallow Dolepin 50 Tablet with a full glass of water.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dolepin 50 Tablet

  •  Increased heart rate
  • Blurred vision
  • Dizziness
  • Dryness in the mouth
  • Weight gain
  • Sudden lowering of blood pressure on standing
  • Difficulty in urination
  • Constipation

Drug Warnings

Dolepin 50 Tablet should be given with extreme caution in patients having epilepsy (Brain disorder in which brain activity becomes abnormal, causing seizures), impaired liver or kidney function, diabetes, decreased level of sodium in the blood, tendency to easily develop bleedings or bruises, patients receiving electroconvulsive treatment, having coronary heart disease, suffering or have suffered from heart problems or have recently had a heart attack, having a low resting heart-rate, having prolonged severe diarrhoea and vomiting (Being sick) or using diuretics (water tablets), experiencing a fast or irregular heartbeat, fainting, collapse, or dizziness on standing up, which may indicate abnormal functioning of the heart rate and having or previously had eye problems, such as certain kinds of glaucoma (increased pressure in the eye).

Drug Interactions

Drug-Drug Interaction: This medicine may have an interaction with other anti-depressants such as phenelzine, iproniazid, isocarboxazid, nialamide, imipramine, and desipramine and tranylcypromine, moclobemide, medicines used to treat Parkinson's disease such as selegiline. Taking this medicine with Dolepin 50 Tablet can increase the risk of side effects. It can also have an interaction with antibiotic linezolid, lithium (used in the treatment of manic-depressive disorder), and tryptophan, medicines used to treat migraines such as Sumatriptan, medicines used for severe pain such as tramadol, medicines used for stomach ulcers such as Cimetidine, lansoprazole, and omeprazole, medicines used to treat fungal infections such as fluconazole, medicines used to reduce the risk of strokes such as ticlopidine, St. John's Wort (Hypericum perforatum) - a herbal remedy used for depression, blood-thinning medicines (warfarin, dipyridamole, and phenprocoumon) and pain killers, antimalarials such as Mefloquine, medicines used for heart diseases such as Flecainide, propafenone, medicines that decrease blood levels of potassium or magnesium, as these increase the risk of life-threatening heart rhythm disorder

Drug-Food Interaction: Dolepin 50 Tablet may interact with multi-mineral or other herbal/ayurvedic supplements. So, if you are using any of the OTC items please tell your doctor.

Drug-Disease Interaction: Obese people (with a BMI greater than 25) should consult a doctor before taking Dolepin 50 Tablet.

Drug-Drug Interactions Checker List

  • PHENELZINE
  • IPRONIAZID
  • ISOCARBOXAZID
  • NIALAMIDE
  • IMIPRAMINE
  • DESIPRAMINE
  • TRANYLCYPROMINE
  • MOCLOBEMIDE
  • SELEGILINE
  • LINEZOLID
  • LITHIUM
  • TRYPTOPHAN
  • SUMATRIPTAN
  • TRAMADOL
  • CIMETIDINE
  • LANSOPRAZOLE
  • OMEPRAZOLE
  • FLUCONAZOLE
  • TICLOPIDINE
  • WARFARIN
  • DIPYRIDAMOLE
  • PHENPROCOUMON
  • MEFLOQUINE
  • FLECAINIDE
  • PROPAFENONE

Habit Forming

No

Diet & Lifestyle Advise

  • Option for healthy food which in turn will help you to elevate your moods.
  • Exercise daily for at least 30 minutes a day. It will help you to reduce stress and improve your mood. It will also improve your quality of sleep.
  • Take deep breaths to calm your mind.
  • Follow a consistent sleep schedule (at least 8 hours a day).
  • Manage your stress levels by doing activities that make you happy such as watching your favourite show, reading a book, listening to music, and activities of your interest.

Special Advise

Do not stop taking dosulepin without talking to your doctor. You may suffer side effects if you stop taking it suddenly. If you and your doctor agree that you should stop taking dosulepin, your doctor will probably recommend reducing your dose gradually over several weeks.

Disease/Condition Glossary

Depression: It is a mood disorder that affects day to day life of a person. A person may have symptoms such as feeling sad or feeling of loss and might have mood swings.

Anxiety: It is defined as an emotion that is characterized by feelings of tension, worried thoughts, and symptoms like increased blood pressure. Anxiety disorder also includes panic disorder which is characterized by sudden feelings of terror.

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Alcohol

Unsafe

It is not recommended to take alcohol while taking Dolepin 50 Tablet to avoid unpleasant side-effects.

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Pregnancy

Unsafe

It is advised not to take Dolepin 50 Tablet during pregnancy as it may pose risk to the unborn baby. However, if you are already taking Dolepin 50 Tablet, please inform your doctor that you are pregnant.

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Breast Feeding

Safe if prescribed

Dolepin 50 Tablet passes in very small amounts in breast milk. It has not been linked with any side-effects. However, caution is advised while taking it. Please inform your doctor if you are breastfeeding.

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Driving

Unsafe

It is not recommended to drive after taking Dolepin 50 Tablet as it can make you feel drowsy.

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Liver

Caution

Caution is advised while taking Dolepin 50 Tablet if you suffer or have suffered from liver diseases.

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Kidney

Caution

Caution is advised while taking Dolepin 50 Tablet if you suffer or have suffered from kidney diseases.

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Children

Unsafe

Dolepin 50 Tablet is not recommended in children below 12 years of age.

Country of origin

India
Other Info - DO19045

Author Details

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FAQs

Dolepin 50 Tablet is used to treat depression and anxiety. It works by increasing the levels of chemical messengers which are responsible for stabilizing and elevating the mood levels in the brain. It also stops your brain from releasing the chemicals which cause anxiety.
Dolepin 50 Tablet helps to elevate your mood levels. After taking it, you easily communicate with other people. It helps you to get better sleep. It helps you to feel like yourself again.
It depends on your symptoms according to which your doctor will advise the dose and duration of Dolepin 50 Tablet. Please inform your doctor if you are planning to switch to any other antidepressant.
Dolepin 50 Tablet is not recommended to treat pain. Rarely, it is advised to treat nerve pain like fibromyalgia or to prevent migraine.
No, Dolepin 50 Tablet is not a habit-forming drug. However, it can cause side-effects especially when you stop taking it suddenly.
Dolepin 50 Tablet might cause weight gain as taking it makes you feel hungry. However, it varies from person to person as some people might feel less hungry after taking it.
Dolepin 50 Tablet starts to show its full effect in 4 to 6 weeks. In case, you feel that you are not feeling better or there is no improvement in the symptoms, please consult your doctor. In case, you feel that you are experiencing any kind of side-effect after taking Dolepin 50 Tablet, please contact your doctor immediately.
Dolepin 50 Tablet may interact with several medications and impact their efficacy. So, taking any medications, including herbal or ayurvedic, other than those prescribed by the doctor is not recommended.
No, it is not a muscle relaxant. Dolepin 50 Tablet is a tricyclic antidepressant medication used to treat depression.
Both Dolepin 50 Tablet and amitriptyline belong to the tricyclic antidepressant class used to treat symptoms of depression. However, do not replace the Dolepin 50 Tablet with amitriptyline unless recommended by the doctor.
Dolepin 50 Tablet and doxepin belong to tricyclic antidepressant class medications used to treat symptoms of depression. However, they may have different mechanisms of action. However, do not replace the Dolepin 50 Tablet with doxepin unless recommended by the doctor.
You may take several weeks or longer to experience the full effect of Dolepin 50 Tablet. Even if you are feeling good, continue to take Dolepin 50 Tablet. Do not discontinue taking Dolepin 50 Tablet without consulting your doctor. Before quitting, your doctor will most likely recommend that you gradually reduce your dose.
Dolepin 50 Tablet is associated with high mortality (death rate) in overdose. There is a low margin of safety between the maximum therapeutic dose and potentially fatal doses. So, you should strictly follow the dose and duration of Dolepin 50 Tablet as directed by the physician. Do not overdose at any cost. If you feel you or someone overdosed or experience any severe adverse events with Dolepin 50 Tablet, consult the doctor or go to the emergency room nearest hospital.
Caution should be exercised. The risk or severity of CNS depression can be increased when Diazepam is combined with Dolepin 50 Tablet.
No. Dolepin 50 Tablet is not intended to treat trigeminal neuralgia (sudden, severe facial pain. It's commonly described as a sudden shooting pain or as an electric shock to the jaw, teeth, or gums.).
No. $ name is not intended to treat burning mouth syndrome (a painful condition often described as a burning, scalding, or tingling feeling in the mouth that may occur every day for months).
Yes, Dolepin 50 Tablet is intended to treat depression. However, it is a prescription medication and should be taken only if the doctor prescribes it to you.
No. Dolepin 50 Tablet is not intended to treat IBS (irritable bowel syndrome). Dolepin 50 Tablet is a tricyclic antidepressant medication used to treat depression.
It is not intended for insomnia with depression alone. However, your doctor may suggest Dolepin 50 Tablet to treat insomnia with depression in some cases. Please consult your doctor for personalized guidance.
Dolepin 50 Tablet can change the way your nerves receive pain signals. This can help with some kinds of nerve pain, including fibromyalgia. However, it should only be taken as prescribed by the doctor.
Dolepin 50 Tablet is sometimes used to treat some types of nerve pain, such as fibromyalgia, or to prevent migraine. But it's not recommended or officially approved for pain relief.
Dolepin 50 Tablet works by increasing levels of a chemical called serotonin in the brain. This can improve your mood.
For depression, it usually takes 4 to 6 weeks for Dolepin 50 Tablet to work fully. However, it varies from person to person.
Dolepin 50 Tablet helps to lift your mood, so you feel better. You may notice that you sleep better and are feeling less anxious. Dolepin 50 Tablet will not change your personality. It'll simply help you feel like yourself again.
No, Dolepin 50 Tablet is not recommended for everyone. It can be harmful to some people and is very dangerous if you take too much. Take personalized guidance from your doctor by letting them know your medical condition and the medications you are taking.
Dolepin 50 Tablet is not addictive, but you may get withdrawal symptoms when you stop taking it, especially if you stop taking it suddenly. Withdrawal symptoms of Dolepin 50 Tablet may include giddiness, headache, insomnia, irritability, increased sweating, nausea, panic-anxiety and restlessness.
Some people feel sleepy while they're taking Dolepin 50 Tablet. If this happens to you, do not drive, cycle or use machinery or tools until you feel better.
It is recommended not to take alcohol while taking Dolepin 50 Tablet. It may make you feel drowsy or may impact how Dolepin 50 Tablet works. So, it would be best to stop drinking alcohol while on treatment.
Limited research is available on Dolepin 50 Tablet in pregnant women. So, talk to your doctor if you are taking Dolepin 50 Tablet and are planning a pregnancy or becoming pregnant. The doctor will help you weigh the risks and benefits to decide on the best treatment for you and your baby. Your mental health must be well treated during pregnancy, as it can affect you and your baby's wellbeing.
No clear evidence suggests that taking Dolepin 50 Tablet will reduce fertility in either men or women. However, speak to a healthcare professional before taking it about its potential benefits and risks.
No, Dolepin 50 Tablet is not recommended for children below 12 years of age. Please seek medical attention if you observe any depression symptoms in your kid.
Symptoms of overdose may include cold body temperature, coma (loss of consciousness for a period of time), feeling agitated, confused, or drowsy, fever, hallucination (seeing things or hearing voices that do not exist), irregular heartbeat, increase in pupil size, muscle stiffness, seizures, trouble concentrating and vomiting.
Take the missed dose as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

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