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  3. Dobion 250mg Injection

Dobion 250mg Injection, Pack of 1 Injection
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Dobion 250mg Injection is used to treat Myocardial infarction and Decompensated heart failure. It contains Dobutamine which works by increasing blood flow to the muscles and increasing the pumping efficiency of the heart. Sometimes, Dobion 250mg Injection may cause common side effects such as headache, nausea, shortness of breath, chest pain, irregular heartbeat and pain at the site of injection. It is not recommended for children as safety and effectiveness are not established.

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Composition :

DOBUTAMINE-250MG

Manufacturer/Marketer :

Biosena Life Sciences

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Dobion 250mg Injection

Dobion 250mg Injection belongs to a class of medicines called vasopressors used to treat patients with low cardiac output, decompensated heart failure (DHF), and Myocardial infarction (MI). Myocardial infarction, also known as a heart attack, could occur due to the lack of blood and oxygen supply to the heart. Cardiac decompensation is an abnormal condition in which the heart is no longer able to maintain efficient circulation.  

Dobion 250mg Injection contains Dobutamine which works by increasing blood flow to the muscles and increasing the pumping efficiency of the heart.

Dobion 250mg Injection will be administered by a healthcare professional. Hence, do not self-administer. Sometimes, Dobion 250mg Injection may cause common side effects such as headache, nausea, shortness of breath, chest pain, irregular heartbeat and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Dobutamine or other ingredients of Dobion 250mg Injection, please inform your doctor. If you are pregnant or breastfeeding or have a history of blood circulation problems, inform your doctor before receiving Dobion 250mg Injection. Dobion 250mg Injection is not recommended for children as safety and effectiveness are not established.

Uses of Dobion 250mg Injection

Treatment of Myocardial infarction and Decompensated heart failure

Directions for Use

Dobion 250mg Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Dobion 250mg Injection contains Dobutamine which is used to treat Cardiac decompensation and low cardiac output patients. It works by increasing blood flow to the muscles. Additionally, it may be used in people with congestive heart failure (heart failure due to the build-up of blood or fluid) to help the heart pump better by increasing the pumping efficiency of the heart.

How Dobion 250mg Injection Works

Dobion 250mg Injection contains Dobutamine which works by increasing blood flow to the muscles and increasing the pumping efficiency of the heart.

Storage

Store in a cool and dry place away from sunlight
Side effects of Dobion 250mg Injection
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
Here's a comprehensive approach to managing medication-triggered high blood pressure (hypertension):
  • Inform your doctor if you experience high blood pressure symptoms after starting a new medication or changing your medication regimen.
  • To reduce high blood pressure symptoms, your doctor may change your medication regimen or dose.
  • Monitor your blood pressure regularly to track changes and potential side effects.
  • Make lifestyle changes, such as following a healthy diet, exercising regularly, and reducing sodium intake.
  • Consider incorporating stress-reducing activities, like meditation or deep breathing exercises, into your daily routine.
  • Create a personalized plan with your doctor to manage high blood pressure, which may include additional medications, therapies, or lifestyle modifications.
  • Follow up with your doctor on a frequent basis to assess progress, change treatment plans, and address any concerns or issues.

What if I have taken an overdose of Dobion 250mg Injection

As Dobion 250mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Dobion 250mg Injection may cause anginal and nonspecific chest pain, anorexia, anxiety, headache, hypertension, myocardial ischaemia, nausea, palpitations, shortness of breath, tachyarrhythmias, tremor, ventricular fibrillation, and vomiting.

Drug Warnings

If you are allergic to Dobutamine or any other ingredients of Dobion 250mg Injection, please tell your doctor. Dobion 250mg Injection is not recommended for children as safety and effectiveness were not established. If you are pregnant or breastfeeding, please inform your doctor before receiving Dobion 250mg Injection. If you have a history of blood circulation problems, inform your doctor, as you will be monitored for any changes in the colour or temperature of your fingers or toes. If you experience any pain or swelling at the injection site during or immediately after the injection, inform your doctor immediately so that appropriate treatment may be given.

Drug-Drug Interactions

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DobutamineNortriptyline
Severe
DobutamineClomipramine
Severe

Drug-Drug Interactions

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DobutamineNortriptyline
Severe
How does the drug interact with Dobion 250mg Injection:
Coadministration of Nortriptyline with Dobion 250mg Injection can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Nortriptyline with Dobion 250mg Injection together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing headaches, tremors, palpitations, or chest pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DobutamineClomipramine
Severe
How does the drug interact with Dobion 250mg Injection:
Taking clomipramine with Dobion 250mg Injection can increase the effects of Dobion 250mg Injection.

How to manage the interaction:
Although taking Dobion 250mg Injection and Clomipramine together can cause an interaction, it can be taken if your doctor has suggested it. It's important to keep an eye on your blood pressure regularly. If you notice any unusual symptoms, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
DobutamineDoxepin
Severe
How does the drug interact with Dobion 250mg Injection:
Doxepin can enhance the blood pressure-raising effects of Dobion 250mg Injection.

How to manage the interaction:
There may be a possibility of interaction between Dobion 250mg Injection and Doxepin, but it can be taken if prescribed by a doctor. If you experience any symptoms contact your doctor immediately. Do not stop using any medications without a doctor's advice.
DobutamineAmitriptyline
Severe
How does the drug interact with Dobion 250mg Injection:
Coadministration of Amitriptyline with Dobion 250mg Injection can enhance the blood pressure-raising effects of Dobion 250mg Injection.

How to manage the interaction:
Although there is a possible interaction between Amitriptyline and Dobion 250mg Injection, you can take these medicines together if prescribed by your doctor. It's important to keep an eye on your blood pressure regularly. If you notice any of these symptoms like Itchy skin or red skin rash, swollen eyes, lips, hands, and feet, feeling lightheaded or dizzy, swelling of the mouth, throat, or tongue, which can cause breathing and swallowing difficulty, coughing, stomach discomfort, nausea, vomiting, or unconsciousness, make sure to consult a doctor. Do not discontinue any medications without consulting a doctor.
DobutamineLinagliptin
Severe
How does the drug interact with Dobion 250mg Injection:
Co-administration of Dobion 250mg Injection and Linagliptin may interfere with blood glucose control and reduce the effectiveness of linagliptin.

How to manage the interaction:
Co-administration of Linagliptin with Dobion 250mg Injection can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat small meals more frequently.
  • Drink plenty of fluids to stay hydrated as dehydration may reduce blood volume resulting in low blood pressure.
  • Include vitamin B12-rich foods such as animal meats, eggs, fortified cereals, and nutritional yeast.
  • Take frequent breaks if you exercise outdoors in extreme heat.
  • Avoid spending a long time in hot tubs, steam rooms, and saunas to prevent dehydration.

Habit Forming

No

Therapeutic Class

VASOPRESSORS

Dobion 250mg Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid consumption of alcohol. Please discuss with your doctor if you have concerns.

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Pregnancy

Caution

Dobion 250mg Injection is considered safe to be used in pregnancy. However, if you are pregnant or planning pregnancy, inform your doctor before receiving Dobion 250mg Injection.

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Breast Feeding

Caution

Limited data are available on the effect of Dobion 250mg Injection on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Dobion 250mg Injection.

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Driving

Not applicable

Dobion 250mg Injection is generally intended for use in hospitalized patients.

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Liver

Caution

If you have liver problems, inform your doctor before receiving Dobion 250mg Injection. Your doctor may adjust the dose of this medicine if necessary or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have kidney problems, inform your doctor before receiving Dobion 250mg Injection. Your doctor may adjust the dose of this medicine if necessary or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Dobion 250mg Injection is not recommended for children as safety and effectiveness were not established in children.

Have a query?

FAQs

Dobion 250mg Injection is used to treat Myocardial infarction and Decompensated heart failure.

Dobion 250mg Injection contains Dobutamine which works by increasing blood flow to the muscles and increasing the pumping efficiency of the heart.

Dobion 250mg Injection should be used with caution in diabetic patients as it may cause Dobutamine stress echocardiography. Therefore, if you have diabetes, inform your doctor before receiving Dobion 250mg Injection.

The common side effects of Dobion 250mg Injection include headache, nausea, shortness of breath, chest pain, irregular heartbeat and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Dobion 250mg Injection can be used for children if recommended by a doctor or paediatrician. It is generally used for the treatment of low cardiac output and systemic blood pressure in children of all ages. However, the dosage will be determined by the doctor based on the child's weight, age, and specific medical condition.

Dobion 250mg Injection is not a steroid. It belongs to a class of medicines called vasopressors and works by increasing blood flow to the muscles and improving the pumping efficiency of the heart. It does not have anti-inflammatory properties like steroids.

Country of origin

India

Manufacturer/Marketer address

SCF-275, 2nd Floor Motor Market, Manimajra Chandigarh- 160101, India
Other Info - DO77774

Disclaimer

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jan 1, 2025 | 2:44 PM IST

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Reference

  1. https://www.drugs.com/mtm/dobutamine.html
  2. https://www.sciencedirect.com/topics/medicine-and-dentistry/dobutamine
  3. https://reference.medscape.com/drug/dobutamine-342434
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