Dobion 250mg Injection belongs to a class of medicines called vasopressors used to treat patients with low cardiac output, decompensated heart failure (DHF), and Myocardial infarction (MI). Myocardial infarction, also known as a heart attack, could occur due to the lack of blood and oxygen supply to the heart. Cardiac decompensation is an abnormal condition in which the heart is no longer able to maintain efficient circulation.  

Dobion 250mg Injection contains Dobutamine which works by increasing blood flow to the muscles and increasing the pumping efficiency of the heart.

Dobion 250mg Injection will be administered by a healthcare professional. Hence, do not self-administer. Sometimes, Dobion 250mg Injection may cause common side effects such as headache, nausea, shortness of breath, chest pain, irregular heartbeat and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Dobutamine or other ingredients of Dobion 250mg Injection, please inform your doctor. If you are pregnant or breastfeeding or have a history of blood circulation problems, inform your doctor before receiving Dobion 250mg Injection. Dobion 250mg Injection is not recommended for children as safety and effectiveness are not established.

Dobion 250mg Injection contains Dobutamine which is used to treat Cardiac decompensation and low cardiac output patients. It works by increasing blood flow to the muscles. Additionally, it may be used in people with congestive heart failure (heart failure due to the build-up of blood or fluid) to help the heart pump better by increasing the pumping efficiency of the heart.

• Headache
• Nausea
• Shortness of breath
• Chest pain
• Irregular heartbeat
• Injection site reactions

If you are allergic to Dobutamine or any other ingredients of Dobion 250mg Injection, please tell your doctor. Dobion 250mg Injection is not recommended for children as safety and effectiveness were not established. If you are pregnant or breastfeeding, please inform your doctor before receiving Dobion 250mg Injection. If you have a history of blood circulation problems, inform your doctor, as you will be monitored for any changes in the colour or temperature of your fingers or toes. If you experience any pain or swelling at the injection site during or immediately after the injection, inform your doctor immediately so that appropriate treatment may be given.

Drug-Drug Interactions: Caution should be maintained if you are taking beta-blockers (propranolol, metoprolol), anticonvulsants (phenytoin), antipsychotics (Amoxapine), anti-depressants (e.g. amitriptyline, clomipramine, imipramine, nortriptyline) inform your doctor before receiving Dobion 250mg Injection.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Avoid receiving Dobion 250mg Injection if you have hyperthyroidism (overactive thyroid gland), irregular or rapid heartbeats or a tumour that causes an increase in blood pressure. If you have a history of blood circulation problems or have diabetes, high blood pressure, Raynaud’s disease (fingers become white and very painful when cold), or liver or kidney problems, inform your doctor before receiving Dobion 250mg Injection.

• NORTRIPTYLINE
• IMIPRAMINE
• PHENYTOIN
• AMITRIPTYLINE
• PROPRANOLOL
• AMOXAPINE
• METOPROLOL

• Eat small meals more frequently.
• Drink plenty of fluids to stay hydrated as dehydration may reduce blood volume resulting in low blood pressure.
• Include vitamin B12-rich foods such as animal meats, eggs, fortified cereals, and nutritional yeast.
• Take frequent breaks if you exercise outdoors in extreme heat.
• Avoid spending a long time in hot tubs, steam rooms, and saunas to prevent dehydration.

Myocardial infarction (MI)/Heart attack: It occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is often an accumulation of fat, cholesterol and other substances, which form plaque in the arteries that feed the heart (coronary arteries). Heart attack signs include chest pain, upper body pain, sweating, nausea, fatigue, and trouble breathing.

Decompensated heart failure (DHF): It is a condition in which the heart is no longer able to maintain efficient circulation. This leads to the sudden onset of symptoms of heart failure.