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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:54 PM IST
Dmp Plus 10 mg/500 mg Tablet is used for the symptomatic treatment of migraine and any medical condition with concomitant nausea/vomiting and fever/pain. It contains Domperidone and Paracetamol, which blocks certain receptors (like dopamine and serotonin) that stimulate the vomiting centre in the brain. It also increases the upper gastrointestinal tract's motility and helps in decreasing the stomach emptying time. It works by blocking the production of prostaglandins (chemicals) that are involved in pain and swelling. Some people may experience side effects such as, dry mouth, skin rash, anxiety, diarrhoea, and drowsiness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Consume Type :

ORAL

Return Policy :

Not Returnable

About Dmp Plus 10 mg/500 mg Tablet

Dmp Plus 10 mg/500 mg Tablet is used for the symptomatic treatment of migraine and any medical condition with concomitant nausea/vomiting and fever/pain. Migraine is a neurological condition that can cause severe throbbing pain or a pulsing sensation, usually on one side of the head, eyes, face, and neck. Symptoms may include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.

Dmp Plus 10 mg/500 mg Tablet is a combination of two drugs: Domperidone and Paracetamol. Domperidone prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone –CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps in decreasing the stomach emptying time. Paracetamol is an NSAID that works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical ‘prostaglandins’(PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Take Dmp Plus 10 mg/500 mg Tablet as prescribed. Your doctor will recommend how often you take Dmp Plus 10 mg/500 mg Tablet based on your medical condition. Some people may experience some side effects, dry mouth, skin rash, anxiety, diarrhoea, and drowsiness. Most of these side effects of Dmp Plus 10 mg/500 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

You can increase the efficacy of Dmp Plus 10 mg/500 mg Tablet by taking a small meal or snacks frequently. Do not take Dmp Plus 10 mg/500 mg Tablet if you are allergic to Dmp Plus 10 mg/500 mg Tablet and other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before taking Dmp Plus 10 mg/500 mg Tablet. Inform your doctor if you have heart, kidney, and liver disease. Prolonged intake of Dmp Plus 10 mg/500 mg Tablet may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking a higher dose. If you experience heart rhythm disorders like palpitations, trouble in breathing, or loss of consciousness after taking Dmp Plus 10 mg/500 mg Tablet, immediately contact your doctor.

Uses of Dmp Plus 10 mg/500 mg Tablet

Treatment of Migraine

Medicinal Benefits

Dmp Plus 10 mg/500 mg Tablet is a combination of two drugs, Domperidone and Paracetamol, used to treat vomiting and pain in people with migraines. Domperidone belongs to a class of prokinetic agents that prevent nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone –CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps in decreasing the stomach emptying time. Paracetamol is an NSAID that works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical ‘prostaglandins’(PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Dmp Plus 10 mg/500 mg Tablet together used to prevent nausea, vomiting, pain, and fever associated with migraine.

Side Effects of Dmp Plus 10 mg/500 mg Tablet

  • Dry mouth
  • Skin rash
  • Anxiety
  • Diarrhea
  • Drowsiness

Directions for Use

Take Dmp Plus 10 mg/500 mg Tablet on an empty stomach or as advised by a doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Dmp Plus 10 mg/500 mg Tablet if you are allergic to any of its contents or any other medicines, have a history of gastrointestinal bleeding, heart disease, liver/ kidney problem. Prolonged intake of Dmp Plus 10 mg/500 mg Tablet may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). So, if you experience heart rhythm disorders like palpitations, trouble in breathing, or loss of consciousness after taking Dmp Plus 10 mg/500 mg Tablet, immediately contact your doctor. This risk may be more likely in the elderly (those over 60 years old) or taking a higher dose. If you are pregnant or breastfeeding, inform your doctor before using Dmp Plus 10 mg/500 mg Tablet. Avoid consumption of alcohol while using Dmp Plus 10 mg/500 mg Tablet as it may increase the side effects and make worse your condition. Dmp Plus 10 mg/500 mg Tablet should not be given to children below five years of age. The use of Dmp Plus 10 mg/500 mg Tablet is safe in children above five years of age if prescribed by the doctor. Do not exceed dose paracetamol more than 4 gm per day as it can damage your liver.

Therapeutic Class

ANTIMIGRAINE AGENTS

Drug-Drug Interactions

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DomperidoneHalofantrine
Severe
DomperidoneClarithromycin
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over sweet food and include more salty food, especially if you have been vomiting.

  • Also, if you like vomiting at a specific time, avoid eating your favorite food at that particular time as your taste for that food may get turned off.

  • Include more cool beverages in your food like clear soup, flavored gelatin, carbonated beverages. Also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas and acidity.

  • Drink after or any other liquid at least 30 minutes after eating food. 

  • Avoid smoking and alcohol intake.

  • Avoid chronic stress as it can raise your migraine pain. Try to enjoy and spending time with your friends to cope with stress and practice mindfulness techniques.

Habit Forming

No

What if I have taken an overdose of Dmp Plus 10 mg/500 mg Tablet

Do not take more than the prescribed dose of Dmp Plus 10 mg/500 mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Country of origin

India
Other Info - DM22753

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