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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Cymevene 500mg Injection is used to treat Cytomegalovirus (CMV) retinitis. It contains Ganciclovir, which kills and stops the cytomegalovirus's growth. Thus, it helps to treat Cytomegalovirus (CMV) retinitis. It is also used to prevent Cytomegalovirus disease in transplant patients at risk for CMV infection. Common side effects of Cymevene 500mg Injection may include nausea, vomiting, loss of appetite, itching, sensitivity to light (photosensitivity), swelling, redness and tenderness at the injection site.
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Composition :

GANCICLOVIR-500MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Cymevene 500mg Injection

Cymevene 500mg Injection belongs to the class of 'antivirals' used in the treatment of cytomegalovirus (CMV) retinitis. Cytomegalovirus (CMV) retinitis is an infection that affects the retina of the eye caused by a virus called Cytomegalovirus (CMV), especially in AIDS patients. It is a serious infection that can lead to blindness. Cymevene 500mg Injection is also used to prevent Cytomegalovirus disease in transplant patients who are at risk for CMV infection.

Cymevene 500mg Injection contains Ganciclovir, which works by killing and stopping the growth of the cytomegalovirus. Thus, helps to treat Cytomegalovirus (CMV) retinitis.

Cymevene 500mg Injection is a parenteral preparation. It will be administered by a healthcare professional; hence do not self-administer. Common side effects of Cymevene 500mg Injection may include nausea, vomiting, loss of appetite, itching, sensitivity to light (photosensitivity), swelling, redness and tenderness at the injection site. These side effects may not occur in every patient using this medication and gradually resolve over time. If the side effects persist longer or worsen, please inform your doctor.

Let your doctor know if you are allergic to any medications. Inform your doctor if you have a weakened immune system, breathing problems, an electrolyte imbalance, blood disorders, and liver or kidney diseases before starting Cymevene 500mg Injection. Cymevene 500mg Injection is not recommended for use in pregnant and breastfeeding women. Hence, inform your doctor before starting Cymevene 500mg Injection. Avoid alcohol consumption while on treatment with Cymevene 500mg Injection to enable your body to fight off infections. Cymevene 500mg Injection should be avoided in children as the safety and efficacy are not explained.

Uses of Cymevene 500mg Injection

Treatment of Cytomegalovirus (CMV) retinitis and Cytomegalovirus disease in transplant patients

Directions for Use

Cymevene 500mg Injection will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Cymevene 500mg Injection treats viral infection of the eye caused by Cytomegalovirus (CMV) retinitis. It is also used to treat Cytomegalovirus disease in transplant patients. Cymevene 500mg Injection consists of Gancyclovir, an antiviral drug that works by killing and stopping the growth of the herpes simplex virus on the cornea.

How Cymevene 500mg Injection Works

Cymevene 500mg Injection contains Ganciclovir, which works by killing and stopping the growth of the cytomegalovirus. Thus, helps to treat Cytomegalovirus (CMV) retinitis.

Storage

Store in a cool and dry place away from sunlight
Side effects of Cymevene 500mg Injection
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
  • Prefer foods high in fiber to help feel full for a long time.
  • If you have decreased appetite, eat only when you are hungry.
  • Eat several small meals or snacks all day.
  • Try to take only small sips of fluids while eating.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Cymevene 500mg Injection

Since Cymevene 500mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

Inform your doctor if you are allergic to Cymevene 500mg Injection or any of the components in Cymevene 500mg Injection. It is advised to inform your doctor that you are pregnant or planning a pregnancy as Cymevene 500mg Injection may cause infertility problems and fetal toxicity. Patients with kidney disease should avoid receiving a name and should notify their doctor. Before beginning treatment with Cymevene 500mg Injection, inform your doctor if you have a history of cancer disease. Nursing mothers should avoid breastfeeding while receiving Cymevene 500mg Injection as it passes in breastmilk and cause side effects to infants.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Cymevene 500mg Injection:
Coadministration of cidofovir with Cymevene 500mg Injection can increase the risk of kidney problems.

How to manage the interaction:
Although there is a interaction between Cymevene 500mg Injection and Cidofovir hence it is not recommended to be taken together, but it can be taken only if advised by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cymevene 500mg Injection:
coadministration of Tenofovir disoproxil with Cymevene 500mg Injection can increase the risk or severity of side effects like kidney damage.

How to manage the interaction:
Although taking Cymevene 500mg Injection and Tenofovir disoproxil together can cause an interaction, it can be taken if your doctor has suggested it. If you have symptoms like feeling sick, not wanting to eat, gaining or losing weight suddenly, holding onto fluids, swelling, trouble breathing, bone or muscle pain, feeling weak or dizzy, feeling confused, or having an irregular heartbeat -contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Cymevene 500mg Injection:
Combining Infliximab with Cymevene 500mg Injection can increase the risk or severity of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Cymevene 500mg Injection and Infliximab, but it can be taken if prescribed by a doctor. If you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate contact your doctor immediately. Don't hesitate to reach out to a doctor if you experience any of these. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cymevene 500mg Injection:
Cymevene 500mg Injection can cause higher levels of Deferiprone in the blood by reducing its excretion rate. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Cymevene 500mg Injection and Deferiprone together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms - like a sore throat, fever, or muscle aches - it's important to let a doctor know right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Cymevene 500mg Injection:
Using zidovudine together with Cymevene 500mg Injection may increase the risk of side effects affecting the blood leading to decreased levels of blood cells.

How to manage the interaction:
Taking Cymevene 500mg Injection with zidovudine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, sore throat, rashes, tiredness, headaches, irritation, confusion, edema, fatigue, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cymevene 500mg Injection:
Using Cymevene 500mg Injection together with etanercept may increase the risk of serious infections.

How to manage the interaction:
There may be a possibility of interaction between Cymevene 500mg Injection and Etanercept, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor.
How does the drug interact with Cymevene 500mg Injection:
Taking cladribine together with Cymevene 500mg Injection may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Cladribine with Cymevene 500mg Injection can result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, or burning while peeing make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cymevene 500mg Injection:
Clozapine can cause higher levels of Cymevene 500mg Injection in the blood by reducing its excretion rate. This can increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Cymevene 500mg Injection and Clozapine, you can take these medicines together if prescribed by a doctor. If you're having any of these symptoms like fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, weight loss, or pain, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Cymevene 500mg Injection:
Using Cymevene 500mg Injection together with adalimumab may increase the risk of serious infections.

How to manage the interaction:
Taking Cymevene 500mg Injection with adalimumab together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GanciclovirGolimumab
Severe
How does the drug interact with Cymevene 500mg Injection:
Using Cymevene 500mg Injection together with golimumab may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction between Cymevene 500mg Injection and Golimumab, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like fever, chills, diarrhea, a sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee contact a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Know your allergy triggers, such as pollen, dust and other factors.
  • Do not rub your eyes even though some ophthalmic drugs make your eye itchy.

Habit Forming

No

Therapeutic Class

ANTIVIRALS
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Alcohol

Consult your doctor

There is limited information on how alcohol consumption affects Cymevene 500mg Injection. Please consult your doctor.

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Pregnancy

Unsafe

Cymevene 500mg Injection may cause fetal toxicity and Impairment of Fertility in males and females. Hence, inform your doctor if you are pregnant before receiving Cymevene 500mg Injection.

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Breast Feeding

Unsafe

Cymevene 500mg Injection is not recommended for use in nursing mothers as it can cause serious side effects to newborn infants. Hence, inform your doctor if you are breastfeeding before receiving this medicine.

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Driving

Caution

Cymevene 500mg Injection causes sleepiness and drowsiness. Do not drive or operate machinery that requires metal alertness.

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Liver

Caution

Inform your doctor if you have any history of liver diseases or hepatic impairment before receiving Cymevene 500mg Injection. Your doctor will advise this medicine only if the benefits outweigh the risks.

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Kidney

Unsafe

Cymevene 500mg Injection is known to cause kidney or renal problems. Hence, inform your doctor if you have any history of kidney diseases before receiving Cymevene 500mg Injection as it can cause serious side effects.

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Children

Caution

The use of Cymevene 500mg Injection is not recommended for children below 16 years of age as the safety and efficacy data are not established.

Have a query?

FAQs

Cymevene 500mg Injection is used to treat Cytomegalovirus (CMV) retinitis and Cytomegalovirus disease in transplant patients.

Cymevene 500mg Injection works by killing and stopping the growth of the cytomegalovirus, thereby helping treat the infection.

Inform your doctor if you are pregnant or a nursing mother before starting treatment with Cymevene 500mg Injection. Maintain caution if you have kidney, liver, or blood disorders, a weakened immune system, breathing problems, and an electrolyte imbalance, as it may worsen your condition. Your doctor will administer Cymevene 500mg Injection only when the benefits outweigh the risks.

Please consult your doctor before you start Cymevene 500mg Injection if you are undergoing any immunizations/vaccinations, especially vaccines against the varicella virus.

Always inform your surgery doctor about the treatment with Cymevene 500mg Injection to avoid serious side effects.

No, as it is an injection, Cymevene 500mg Injection will be administered by the trained healthcare professional. Hence do not administer it.

Inform your doctor about any eye problems other than CMV retinitis. Do not use any medicine without consulting the doctor.

Country of origin

INDIA

Manufacturer/Marketer address

Roche Diagnostics India Pvt Ltd, 501 B, Silver Utopia, Cardinal Gracious Road, Chakala Road, Andheri East, Mumbai – 400069
Other Info - CYM0001

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