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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 13, 2024 | 12:53 PM IST

Colorifax 200 Tablet is used to treat infectious traveller's diarrhoea caused by E.coli bacteria, hepatic encephalopathy (decreased brain function due to liver disease) and irritable bowel syndrome with diarrhoea (IBS-D). It contains Rifaximin, which works by working on the bowel and preventing the spread of infections caused by the loss of beneficial gut bacteria. Thus, it helps in relieving abdominal pain and diarrhoea. In some cases, you may experience certain common side effects such as headache, peripheral oedema (leg swelling), nausea, dizziness, fatigue, ascites (excess fluid build-up in the abdomen), increased liver enzymes (ALT), and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition

RIFAXIMIN-200MG

Manufacturer/Marketer

Gutford Pharmaceuticals

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Colorifax 200 Tablet

Colorifax 200 Tablet used to treat infectious traveller's diarrhoea caused by E.coli bacteria, hepatic encephalopathy (decreased brain function due to liver disease) and irritable bowel syndrome with diarrhoea (IBS-D). Traveller’s diarrhoea is an infection in which there is a passage of unformed stools. Hepatic encephalopathy causes loss of brain function when a damaged liver is unable to remove toxins from the blood. Irritable bowel syndrome is a condition which affects the large intestine. 

Colorifax 200 Tablet contains ‘Rifaximin’, which works by working on the bowel and preventing the spread of infections caused by the loss of beneficial gut bacteria.  Thus, Colorifax 200 Tablet helps in relieving abdominal pain and diarrhoea. Colorifax 200 Tablet should not be used in patients with diarrhoea complicated by fever or blood in the stool and diarrhoea due to pathogens other than Escherichia coli (E.coli).

Take Colorifax 200 Tablet with or without food. In some cases, you may experience certain common side effects such as headache, peripheral oedema (leg swelling), nausea, dizziness, fatigue, ascites (excess fluid build-up in the abdomen), increased liver enzymes (ALT), and nausea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Colorifax 200 Tablet , please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Colorifax 200 Tablet for more than 3 days unless prescribed; if there is no symptomatic improvement, consult your doctor. Avoid taking Colorifax 200 Tablet if you are pregnant or breastfeeding; talk to your doctor; he/she may prescribe you alternate medicine. Colorifax 200 Tablet is not recommended for children as efficacy and safety have not been established. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects.

Uses of Colorifax 200 Tablet

Treatment of travelles diarrhoea, liver encephalopathy, and irritable bowel syndrome due to diarrhoea.

Medicinal Benefits

Colorifax 200 Tablet belongs to the group of medicines called antibiotics used to treat infectious travellers diarrhoea, hepatic encephalopathy (decrease in brain function due to liver disease) and irritable bowel syndrome (IBS). Colorifax 200 Tablet is used to treat traveller’s diarrhoea caused by non-invasive strains of E.coli. Colorifax 200 Tablet is a broad-spectrum antibiotic that is effective against gram-positive and gram-negative bacteria, aerobic and anaerobic bacteria, and ammonia-producing bacteria. Colorifax 200 Tablet is a gastrointestinal-selective antibiotic with a broad spectrum of antimicrobial activity. Colorifax 200 Tablet is bactericidal in nature and works by killing the bacteria that cause infections. Thus, it helps in treating and preventing the spread of infections.

Directions for Use

Swallow the medicine as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Colorifax 200 Tablet

  • Headache
  • Peripheral oedema (leg swelling)
  • Nausea
  • Dizziness
  • Fatigue
  • Ascites (excess fluid build-up in the abdomen)
  • Increased liver enzymes (ALT)

Drug Warnings

Do not take Colorifax 200 Tablet if you are allergic to any of its contents, if you have a fever, blood in stools, passed 8 or more unformed stools in the last 24 hours, constipation, vomiting, and abdominal pain caused by blockage of the bowel. Talk to your doctor if your condition does not improve, symptoms continue or re-appear even after taking Colorifax 200 Tablet for 3 days. Do not take Colorifax 200 Tablet for more than 3 days unless prescribed; if there is no symptomatic improvement, consult your doctor. Avoid taking Colorifax 200 Tablet if you are pregnant or breastfeeding; talk to your doctor; he/she may prescribe you with alternate medicine. Colorifax 200 Tablet is not recommended for children below 12 years of age as the efficacy and safety have not been established. Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects. Patients with liver complications should avoid taking Colorifax 200 Tablet or consult a doctor before using Colorifax 200 Tablet .

Drug Interactions

Drug-Drug Interactions: Colorifax 200 Tablet may interact with the immune system, affecting drugs (cyclosporine) and blood thinners (warfarin). 

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Colorifax 200 Tablet should not be taken by people with colitis (inflammation in the lining of the colon), liver disease and diarrhoea caused by other than E coli bacteria.

Drug-Drug Interactions Checker List

  • CYCLOSPORINE
  • WARFARIN

Habit Forming

No

Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which helps indigestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, such as grapefruit and grapefruit juice, as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol to treat your condition effectively.
  • Avoid the usage of tobacco.

Special Advise

  • Prolonged intake of Colorifax 200 Tablet may cause diarrhoea caused by an overgrowth of bacteria known as C. difficile. This can cause mild to severe diarrhoea to life-threatening colitis (colon inflammation).
  • Monitor bleeding time parameters like INR and prothrombin time while using Colorifax 200 Tablet .

Disease/Condition Glossary

Traveller’s diarrhoea: It is an intestinal infection in which there is the passage of unformed stools due to eating or drinking contaminated food or water while travelling. Symptoms include nausea, vomiting, bloating, fever, gas, loss of appetite, and the urgent need to poop.

Hepatic/liver encephalopathy: It is a decrease in brain function due to liver disease. The liver cannot remove toxins from the body adequately, which results in a buildup of toxins in the blood, thereby leads to brain damage. Symptoms include confusion, forgetfulness, difficulty thinking, low concentration, personality changes, and problems with small hand movements.

Irritable bowel syndrome (IBS): It is a condition which affects the large intestine. Symptoms include abdominal pain, cramps, gas, constipation, and diarrhoea.

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Alcohol

Caution

Please consult your doctor as it is not known whether alcohol affects the working of Colorifax 200 Tablet . However, you are advised to limit or avoid alcohol consumption to prevent unpleasant side-effects.

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Pregnancy

Caution

It is not recommended to take Colorifax 200 Tablet while you are pregnant. Please consult your doctor if you have any concerns regarding this, your doctor will decide whether Colorifax 200 Tablet can be given to pregnant women or not.

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Breast Feeding

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will decide whether Colorifax 200 Tablet can be given to breastfeeding mothers or not.

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Driving

Safe if prescribed

Colorifax 200 Tablet does not affect your ability to drive. However, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Please consult your doctor if you have any concerns regarding this or if you have liver impairment/liver disease before taking Colorifax 200 Tablet .

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Kidney

Caution

Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Colorifax 200 Tablet .

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Children

Unsafe

Colorifax 200 Tablet is not recommended for children as the efficacy and safety have not been established.

Country of origin

India

Manufacturer/Marketer address

3/97-2, Hospital Road, Chenbagaramanputhoor, Thovalai Taluk, Kanyakumari Dist - 629301
Other Info - COL1551

Author Details

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FAQs

Colorifax 200 Tablet is used to treat infectious traveller's diarrhoea caused by E.coli bacteria, hepatic encephalopathy (decreased brain function due to liver disease) and irritable bowel syndrome with diarrhoea (IBS-D).
Colorifax 200 Tablet is bactericidal in nature and works by killing the harmful bacteria that cause infections in the gut or intestine like E coli bacteria. Thereby, helps in treating/preventing the spread of infections and diarrhoea with abdominal pain.
It is recommended to complete the course of Colorifax 200 Tablet even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).
Do not take Colorifax 200 Tablet on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Take Colorifax 200 Tablet only if prescribed by a doctor.
Colorifax 200 Tablet may affect blood tests and liver function tests with increased liver enzymes. Inform the person or doctor before performing the tests that you are taking Colorifax 200 Tablet .
For treating traveller's diarrhoea, Colorifax 200 Tablet is generally prescribed for 3 days. For irritable bowel syndrome, Colorifax 200 Tablet is prescribed for 14 days. However, it is better to take Colorifax 200 Tablet only as prescribed by your doctor.
No, Colorifax 200 Tablet may affect the activity and working of warfarin when taken together. So tell your doctor before using Colorifax 200 Tablet that you are taking a blood thinner (warfarin). Your doctor might adjust the dose of warfarin to maintain the proper blood-thinning effect and prevent drug interaction.
Do not take Colorifax 200 Tablet for more than 3 days unless prescribed; if there is no symptomatic improvement, consult your doctor.
Colorifax 200 Tablet should not be used in patients with diarrhoea complicated by fever or blood in the stool and diarrhoea due to pathogens other than Escherichia coli (E. coli).
Take Colorifax 200 Tablet exactly as prescribed by the doctor. Take it at the same time daily as it will help you to remember taking the medication.
Colorifax 200 Tablet contains Rifaximin used to treat infectious traveller’s diarrhoea, hepatic encephalopathy (decrease in brain function due to liver disease) and irritable bowel syndrome.
Side effects of Colorifax 200 Tablet include headache, peripheral oedema (leg swelling), nausea, dizziness, fatigue, ascites (excess fluid build-up in the abdomen), increased liver enzymes (ALT), and nausea. Talk to your doctor if you experience these side effects persistently.
Colorifax 200 Tablet is an antimycobacterial which works by killing the bacteria that cause infection.
Colorifax 200 Tablet can be taken with or without food.
Colorifax 200 Tablet decreases the symptoms in case of liver disease by killing harmful bacteria in the gut. Thereby it helps lower the possibility of toxins.
Colorifax 200 Tablet may not cause weight gain. Maintain proper weight by eating healthy and doing exercise. Consult the doctor if you notice changes in your weight.

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