Colonext-AD-DS Dry Suspension belongs to the class of medications called ‘antibiotics’ used to treat bacterial infections caused by susceptible Gram-negative bacteria. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.

Colonext-AD-DS Dry Suspension contains Colistin Sulphate. Colistin effectively solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, Colonext-AD-DS Dry Suspension destroys the bacteria and successfully treats the infection.

Take Colonext-AD-DS Dry Suspension as prescribed by your doctor. Depending on your medical condition, you are advised to take Colonext-AD-DS Dry Suspension for as long as your doctor prescribes it. Sometimes, you may experience common side effects like dizziness, upset stomach, rash, diarrhoea, vertigo (spinning sensation), paresthesia (tingling or pricking sensation) and slurred speech. But these side effects are usually in the initial phase and resolve over time. However, if these side effects persist, let your doctor know.

Before receiving Colonext-AD-DS Dry Suspension, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Colonext-AD-DS Dry Suspension can cause blurred vision and dizziness in some people; if this occurs, do not drive or operate tools or machinery. It is recommended not to consume any alcoholic beverages while on treatment with this medicine.

Colonext-AD-DS Dry Suspension contains Colistin Sulphate, which is used for treating acute or chronic infections due to sensitive strains of certain gram-negative bacilli, particularly Pseudomonas aeruginosa. Colistin sulphate effectively solubilizes the bacterial cell membrane, resulting in bacterial cell death. As a result, Colonext-AD-DS Dry Suspension destroys the bacteria and successfully treats the infection.

• Dizziness
• Upset stomach
• Rash
• Diarrhoea
• Kidney damage
• Vertigo (Spinning sensation)
• Paresthesia (tingling or pricking sensation)
• Slurred speech

Before taking the Colonext-AD-DS Dry Suspension, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Inform your doctor if you are pregnant, planning to become pregnant, or are breastfeeding before receiving Colonext-AD-DS Dry Suspension. Also, inform your doctor if you have chronic kidney disease, myasthenia gravis (muscle disorder), and porphyria (a blood disorder). Do not abruptly discontinue taking the prescription since this may result in antibiotic resistance, a condition in which bacteria develop resistance to antibiotics.

Drug-Drug Interactions: Colonext-AD-DS Dry Suspension is known to interact with selective skeletal muscle relaxants (e.g. cyclobenzaprine, metaxalone), antifungals (e.g. amphotericin B) and aminoglycosides (e.g. capreomycin, vancomycin)

Drug-Food Interactions: Colonext-AD-DS Dry Suspension is known to interact with alcohol and Grapefruit.

Drug-Disease Interactions: Colonext-AD-DS Dry Suspension is known to interact with disease conditions, including kidney problems, myasthenia gravis (a muscle disorder), and porphyria (a blood disorder).

• AZITHROMYCIN
• CLARITHROMYCIN
• ERYTHROMYCIN
• OFLOXACIN
• NORFLOXACIN
• CIPROFLOXACIN
• NETILIMICIN
• GENTAMICIN
• AMIKACIN
• TOBRAMYCIN
• ATRACURIUM
• CISATRACURIUM
• VECURONIUM

• After taking the full course of Colonext-AD-DS Dry Suspension, probiotics should be taken to restore some of the healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can restore the intestine's good bacteria stink.
• Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread and brown rice, should be included in your diet.
• Avoid taking many calcium-enriched foods and drinks as it might affect the working of Colonext-AD-DS Dry Suspension.
• Avoid intake of alcoholic beverages with Colonext-AD-DS Dry Suspension as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Colonext-AD-DS Dry Suspension in fighting off infections.

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. It can target any organ of the body and multiply very quickly. Many give off chemicals called toxins, which can damage tissue and make you sick. Bacterial infections vary from minor illnesses (like sore throat and ear infections) to severe brain infections (like meningitis and encephalitis). When you get infected with bacteria, you can experience generalized symptoms like fevers, chills and fatigue. A few harmful bacteria commonly cause infections, including Streptococcus, Staphylococcus and E. coli. Anyone can get a bacterial infection, but people with a weak immune system or taking immunosuppressive medicines like steroids are more prone to infections.