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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:50 PM IST
Clarsaf 125mg Tablet DT is used to treat a wide range of bacterial infections, including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection, the affected skin appears swollen and red and is typically painful and warm to the touch), and ear infections. Besides this, it is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. It contains Clarithromycin, which inhibits the growth of bacteria. It may cause some common side effects, such as nausea, diarrhoea, vomiting, loss of appetite, bloating, indigestion, headaches and difficulty sleeping. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Return Policy :

Not Returnable

About Clarsaf 125mg Tablet DT

Clarsaf 125mg Tablet DT is used to treat a wide range of bacterial infections, including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection, the affected skin appears swollen and red and is typically painful and warm to the touch), and ear infections. Besides this, Clarsaf 125mg Tablet DT is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori.

Clarsaf 125mg Tablet DT contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Clarsaf 125mg Tablet DT helps prevent infections.

Clarsaf 125mg Tablet DT should only be if your doctor has prescribed you. Clarsaf 125mg Tablet DT should not be stopped even if you feel better as it is an antibiotic medication, and completing the full course is necessary; otherwise, the infection might re-appear in a more severe form. Like all medicines, Clarsaf 125mg Tablet DT may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), losing your appetite, bloating and indigestion, headaches and difficulty sleeping. These side effects are temporary and may get resolved after some time; however, if this side persists, let your doctor know about this if you notice any sudden wheeziness, tightness in the chest or throat, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body) STOP TAKING your medicine and go to a doctor immediately.

Do not take Clarsaf 125mg Tablet DT if allergic to azithromycin, other macrolide antibiotics, or any components present in Clarsaf 125mg Tablet DT. Clarsaf 125mg Tablet DT isn't normally recommended during pregnancy and while breastfeeding. But your doctor may prescribe it if the benefits of taking it are greater than the risks. Do not consume alcohol as it may cause excessive drowsiness when taken along with Clarsaf 125mg Tablet DT. Before using the Clarsaf 125mg Tablet DT, tell your doctor if you ever had an allergy to Clarsaf 125mg Tablet DT have kidney problems, liver problems, swollen food pipe (oesophagitis), lupus disease (an autoimmune disease), or muscle disease (myasthenia gravis). Do not drink alcohol with Clarsaf 125mg Tablet DT as it may increase the unpleasant side effects like drowsiness and dizziness.

Uses of Clarsaf 125mg Tablet DT

Treatment of Bacterial infections

Medicinal Benefits

Clarsaf 125mg Tablet DT is a type of macrolide class of antibiotic which is effective against a wide range of bacteria, including gram-negative and gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections, including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori). Clarsaf 125mg Tablet DT is sometimes used by people who have an allergy to penicillin and antibiotics similar to penicillin, such as amoxicillin.

Side Effects of Clarsaf 125mg Tablet DT

  • Headache

  • Diarrhoea

  • Being sick (vomiting)

  • Nausea (feeling sick)

  • Loss of appetite

  • Taste change

  • Bloating

  • Indigestion

  • Abdominal pain

  • Insomnia (difficulty sleeping)

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Clarsaf 125mg Tablet DT in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Clarsaf 125mg Tablet DT and iron supplements and antacids. Besides this, in some cases, the use of Clarsaf 125mg Tablet DT causes antibiotic-associated diarrhoea. Clarsaf 125mg Tablet DT may cause sensitive skin to sunlight and ultraviolet rays, causing an exaggerated sunburn reaction. Hence it is advisable to apply sunscreen before going outside. Its use has also been associated with an increased risk of fungal skin infections like (vaginal candidiasis - thrush). Tetracycline and Clarsaf 125mg Tablet DT can form a stable calcium complex in bone-forming tissue, thereby affecting the growth of fibula bones in young children and bone development in the foetus. Using a Clarsaf 125mg Tablet DT with isotretinoin should be avoided as it has been reported to cause pseudotumor cerebri (increased pressure inside the brain). Long-term use of Clarsaf 125mg Tablet DT may affect your blood, kidney, and liver health, so yearly diagnostics test of these parameters is recommended.

Therapeutic Class

ANTI- BACTERIALS

Diet & Lifestyle Advise

  • Probiotics and prebiotics can also help to reduce the side effects of antibiotics.

  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. 

  • Eating grapefruit during antibiotics treatment can prevent the body from utilizing Clarsaf 125mg Tablet DT properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic. 

  • Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of Clarsaf 125mg Tablet DT. 

  • Avoid intake of alcoholic beverages with Clarsaf 125mg Tablet DT as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Clarsaf 125mg Tablet DT in fighting off infections.

Habit Forming

No

How Clarsaf 125mg Tablet DT Works

Clarsaf 125mg Tablet DT contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Clarsaf 125mg Tablet DT helps prevent infections.

What if I have taken an overdose of Clarsaf 125mg Tablet DT

Do not take more than the prescribed dose of Clarsaf 125mg Tablet DT as it may cause overdose. The symptoms of overdose include diarrhoea, vomiting, nausea and stomach pain. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.
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Alcohol

Unsafe

Clarsaf 125mg Tablet DT should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol.

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Pregnancy

Caution

Clarsaf 125mg Tablet DT should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Let your doctor know if you are a nursing mother before taking Clarsaf 125mg Tablet DT; your doctor will decide whether Clarsaf 125mg Tablet DT can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Not enough scientific data available for Clarsaf 125mg Tablet DT, hence it is advised to consult your doctor.

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Liver

Caution

Clarsaf 125mg Tablet DT to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Clarsaf 125mg Tablet DT to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Clarsaf 125mg Tablet DT can be given safely to children in the form of suspension only, dose to be adjusted and recommended by a child specialist only.

Country of origin

India
Other Info - CL63161

Author Details

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FAQs

Clarsaf 125mg Tablet DT is used to treat bacterial infections, including chest infections, skin infections, and ear infections. Besides this, Clarsaf 125mg Tablet DT is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori.
Clarsaf 125mg Tablet DT contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Clarsaf 125mg Tablet DT helps in the prevention of infections.
You should avoid taking iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking Clarsaf 125mg Tablet DT. Avoid taking any other antibiotics containing Clarsaf 125mg Tablet DT unless your doctor has prescribed you.
After taking antibiotics such as Clarsaf 125mg Tablet DT, some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.
Clarsaf 125mg Tablet DT treats only bacterial infections. It will not work for viral infections (such as common cold, flu).
No, Clarsaf 125mg Tablet DT is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with doctor advice only.
Side-effects are rare with Clarsaf 125mg Tablet DT and do not usually last long. They will get better after a day or two. if those side effects persist reach out to the doctor immediately.​
No, Clarsaf 125mg Tablet DT should not be stopped even if you feel better as it is an antibiotic medication and completing the full course if very necessary; otherwise, the infection might re-appear in a more severe form.

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