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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST

Ca-Astrans-10 mg Capsule 30's belongs to a class of drugs called retinoids which is used in the treatment of acne. This medicine works by inhibiting the acne-causing microbes and unblocks pores. Common side effects include dryness of skin, redness, skin irritation, pain or skin flaking.

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Composition

TRETINOIN-10MG

Manufacturer/Marketer

ASTOR PHARMACEUTICALS PVT LTD

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Ca-Astrans-10 mg Capsule 30's

Ca-Astrans-10 mg Capsule 30's belongs to a class of drugs called retinoids (similar to vitamin A). Ca-Astrans-10 mg Capsule 30's is used to treat acute promyelocytic leukaemia (a type of blood problem). Acute promyelocytic leukaemia is a blood cancer that causes a marked increase in a type of immature white blood cells known as promyelocytes in the blood and bone marrow. 

Ca-Astrans-10 mg Capsule 30's contains Tretinoin, a form of vitamin A that works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.

Take Ca-Astrans-10 mg Capsule 30's as prescribed. Your doctor will advise you how often you need to take Ca-Astrans-10 mg Capsule 30's based on your medical condition. Some people may experience dizziness, headache, feeling tired, stomach pain, irregular heartbeat, hair loss, bone or joint pain, dry skin and changes in eyesight or hearing. Most of these side effects of Ca-Astrans-10 mg Capsule 30's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Tretinoin, peanuts, soya or any other ingredients in Ca-Astrans-10 mg Capsule 30's, please tell your doctor. Avoid taking Ca-Astrans-10 mg Capsule 30's if you are pregnant as it may harm the foetus. Avoid breastfeeding while taking Ca-Astrans-10 mg Capsule 30's as it is excreted into breast milk and may harm the baby. Avoid taking Ca-Astrans-10 mg Capsule 30's if you are taking other retinoid medicines (acitretin, tazarotene, isotretinoin), vitamin A and tetracyclines (antibiotics). If you are allergic to any sugars, please inform your doctor before taking Ca-Astrans-10 mg Capsule 30's as it may contain sorbitol.

Uses of Ca-Astrans-10 mg Capsule 30's

Treatment of Acute promyelocytic leukaemia

Medicinal Benefits

Ca-Astrans-10 mg Capsule 30's is a form of vitamin A that is primarily used to treat acute promyelocytic leukaemia (a type of blood problem). Ca-Astrans-10 mg Capsule 30's reduces the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.  

Directions for Use

Take Ca-Astrans-10 mg Capsule 30's preferably with a meal or as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ca-Astrans-10 mg Capsule 30's

  • Dizziness
  • Headache
  • Feeling tired
  • Stomach pain
  • Irregular heartbeat
  • Hair loss
  • Bone or joint pain
  • Dry skin
  • Changes in eyesight or hearing

Drug Warnings

If you are allergic to Tretinoin, peanuts, soya or any other ingredients, please tell your doctor. Avoid taking Ca-Astrans-10 mg Capsule 30's if you are pregnant as it may harm the foetus. Avoid breastfeeding while taking Ca-Astrans-10 mg Capsule 30's as it is excreted into breast milk and may harm the baby. You are advised to use effective contraceptive methods while using Ca-Astrans-10 mg Capsule 30's to prevent pregnancy. Avoid taking Ca-Astrans-10 mg Capsule 30's if you are taking other retinoid medicines (acitretin, tazarotene, isotretinoin), vitamin A and tetracyclines (antibiotics). If you are allergic to any sugars, please inform your doctor before taking Ca-Astrans-10 mg Capsule 30's as it may contain sorbitol.

Drug Interactions

Drug-Drug Interaction: Ca-Astrans-10 mg Capsule 30's may interact with antibiotics (erythromycin, clarithromycin, rifampicin, tetracyclines), vitamin A, retinoids, low-dose progestogens, antifungal (ketoconazole, itraconazole, posaconazole, fluconazole), corticosteroids (dexamethasone, prednisolone), anticonvulsants (phenobarbital), anti-HIV medicines (saquinavir, ritonavir), heart-related medicines (diltiazem, verapamil), drugs for stomach ulcers (cimetidine), immunosuppressant (ciclosporin) and medicines to reduce bleeding (aprotinin, aminocaproic acid, tranexamic acid).

Drug-Food Interaction: No interactions found. 

Drug-Disease Interaction: If you have ever had any mental health problems including mood changes, depression or aggressive tendencies, inform your doctor before taking Ca-Astrans-10 mg Capsule 30's.

Drug-Drug Interactions Checker List

  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • RIFAMPICIN
  • TETRACYCLINE
  • VITAMIN A
  • KETOCONAZOLE
  • ITRACONAZOLE
  • POSACONAZOLE
  • FLUCONAZOLE
  • DEXAMETHASONE
  • PREDNISOLONE
  • PHENOBARBITAL
  • SAQUINAVIR
  • RITONAVIR
  • DILTIAZEM
  • VERAPAMIL
  • CIMETIDINE
  • CICLOSPORIN
  • APROTININ
  • AMINOCAPROIC ACID
  • TRANEXAMIC ACID

Habit Forming

No

Diet & Lifestyle Advise

  • Eat 5 portions of vegetables and fruits in a day.
  • Reduce the intake of salt and fat.

  • Regular exercise may help to reduce depression and excessive tiredness after treatment.

  • Start with gentle walking and once your white blood cell count comes back to normal, you can go swimming.

  • Avoid alcohol consumption.

Special Advise

Ca-Astrans-10 mg Capsule 30's may affect your mood and behaviour. Therefore, you are recommended to inform your family and friends that you are taking Ca-Astrans-10 mg Capsule 30's so that they may notice any changes and help you identify problems that are needed to be discussed with your doctor.

Disease/Condition Glossary

Acute promyelocytic leukaemia (APL): It is a blood cancer that causes a marked increase in a type of immature white blood cells known as promyelocytes in the blood and bone marrow. The symptoms of APL include blood in the urine, nosebleeds, loss of appetite, extreme tiredness, unexplained bruising or excessive bleeding from small cuts.

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Alcohol

Caution

Interaction of alcohol with Ca-Astrans-10 mg Capsule 30's is unknown. Please consult a doctor before consuming alcohol while using Ca-Astrans-10 mg Capsule 30's.

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Pregnancy

Unsafe

Ca-Astrans-10 mg Capsule 30's is Category C pregnancy drug and is considered unsafe for pregnant women as it may harm the unborn baby.

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Breast Feeding

Unsafe

Ca-Astrans-10 mg Capsule 30's is excreted into breast milk and may harm the baby. Therefore, you are recommended to avoid breastfeeding while taking Ca-Astrans-10 mg Capsule 30's.

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Driving

Caution

Ca-Astrans-10 mg Capsule 30's may cause dizziness or severe headache. Therefore, drive only if you alert after taking Ca-Astrans-10 mg Capsule 30's.

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Liver

Caution

Take Ca-Astrans-10 mg Capsule 30's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Ca-Astrans-10 mg Capsule 30's with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Ca-Astrans-10 mg Capsule 30's should be given to children only in doses advised by the doctor.

Country of origin

India

Manufacturer/Marketer address

SAH-38, Jaipuria Mall, Indirapuram Ghaziabad-201014
Other Info - CAA0018

Author Details

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FAQs

Ca-Astrans-10 mg Capsule 30's belongs to a class of drugs called retinoids (similar to vitamin A). Ca-Astrans-10 mg Capsule 30's is used to treat acute promyelocytic leukaemia (a type of blood problem).
Ca-Astrans-10 mg Capsule 30's works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.
You are recommended to avoid pregnancy while taking Ca-Astrans-10 mg Capsule 30's and for 1 month after stopping treatment with Ca-Astrans-10 mg Capsule 30's as it may cause the birth of the deformed baby. Therefore, you are advised to use effective contraceptive measures while taking Ca-Astrans-10 mg Capsule 30's and for 1 month after stopping treatment with Ca-Astrans-10 mg Capsule 30's to prevent pregnancy. Also, women using Ca-Astrans-10 mg Capsule 30's should take a pregnancy test every month and if you become pregnant while taking Ca-Astrans-10 mg Capsule 30's, inform your doctor immediately.
Ca-Astrans-10 mg Capsule 30's may cause dizziness as a temporary side effect. Therefore, drive only if you are alert after taking Ca-Astrans-10 mg Capsule 30's.
You are not recommended to take low-dose progestogens (mini pill) with Ca-Astrans-10 mg Capsule 30's as their effectiveness may be reduced. However, discuss with your doctor if you have any concerns regarding this so that a different oral contraceptive may be prescribed.
Ca-Astrans-10 mg Capsule 30's may cause painful swelling in the leg in a few patients. If you experience painful swelling in your leg, difficulty breathing or sudden chest pain while taking Ca-Astrans-10 mg Capsule 30's, please inform your doctor immediately as these might be signs of a blood clot.

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