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Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 9:32 AM IST

Bicnu 100 mg Injection is used in the treatment of brain tumors. Bicnu 100 mg Injection is also used in the treatment of multiple myeloma in combination with prednisone, Hodgkin’s Disease, and non-Hodgkin’s Disease in combination with other approved drugs. It contains Carmustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

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Prescription drug

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Composition :

CARMUSTINE-100MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Bicnu 100 mg Injection

Bicnu 100 mg Injection is a chemotherapeutic medicine used in the treatment of brain tumors. A tumor is defined as the formation of solid mass tissue due to the abnormal growth of cells. A brain tumor is a serious condition where the cells (cancerous or non-cancerous) grow abnormally in the brain. Bicnu 100 mg Injection is also used in the treatment of multiple myeloma in combination with prednisone, Hodgkin’s Disease, and non-Hodgkin’s Disease in combination with other approved drugs.

Bicnu 100 mg Injection contains Carmustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

Bicnu 100 mg Injection may cause certain side effects, such as nausea, vomiting, headache, pale skin, dizziness, stomach upset, tiredness, loss of balance, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Bicnu 100 mg Injection is a parenteral preparation. A trained healthcare professional will administer it. Hence, do not self-administer.

Bicnu 100 mg Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, or respiratory conditions. Bicnu 100 mg Injection may cause pulmonary toxicity, bone marrow suppression, gastrointestinal toxicity, nephrotoxicity and hepatotoxicity in some patients. Hence, careful monitoring should be done during the entire treatment. This medicine is known to cause fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. Breastfeeding should be discontinued in nursing mothers during the treatment.

Uses of Bicnu 100 mg Injection

Treatment of Brain Tumors, Multiple Myeloma, Hodgkin's Disease and Non-Hodgkin's Disease

Medicinal Benefits

Bicnu 100 mg Injection contains Carmustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

Side Effects of Bicnu 100 mg Injection

  • Nausea
  • Dizziness
  • Stomach upset
  • Headache
  • Vomiting
  • Pale skin
  • Tiredness
  • Loss of balance
  • Diarrhoea
  • Cough
  • Decreased platelet count
  • Bruising or bleeding gums
  • Pain at the site of injection

Directions for Use

Bicnu 100 mg Injection will be administered by a trained healthcare professional. Hence, do not self-administer. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Bicnu 100 mg Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, or respiratory conditions. Bicnu 100 mg Injection may cause pulmonary toxicity, bone marrow suppression, gastrointestinal toxicity, nephrotoxicity and hepatotoxicity in some patients. Hence careful monitoring should be done during the entire treatment. This medicine is known to cause fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. Breastfeeding should be discontinued in nursing mothers during the treatment. It is unknown whether Bicnu 100 mg Injection can be administered in children or not. If administered, close monitoring of the child is needed. Avoid alcohol consumption and smoking as it can lead to serious adverse effects.

Therapeutic Class

CHEMOTHERAPY

Drug-Drug Interactions

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CarmustineInfliximab
Severe
CarmustineLeflunomide
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

How Bicnu 100 mg Injection Works

Bicnu 100 mg Injection contains Carmustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This causes shrinkage of tumor cells and thereby prevents the growth and further spread of cancerous or non-cancerous cells.

What if I have taken an overdose of Bicnu 100 mg Injection

As Bicnu 100 mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Bicnu 100 mg Injection to prevent serious adverse effects.

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Pregnancy

Unsafe

Bicnu 100 mg Injection is not recommended for use in pregnancy as it may harm your fetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Bicnu 100 mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Limited data is available on the effect of Bicnu 100 mg Injection on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving Bicnu 100 mg Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Bicnu 100 mg Injection will be administered in the hospital setting. Hence, avoid driving.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Bicnu 100 mg Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Bicnu 100 mg Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Children

Consult your doctor

Limited information is available for the use of Bicnu 100 mg Injection in children. Hence, it will be given to the children only if needed. If administered, careful monitoring of the child is needed.

Country of origin

India

Manufacturer/Marketer address

A €“ 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat
Other Info - BIC0045

Author Details

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FAQs

Bicnu 100 mg Injection is used to treat Brain Tumors, Multiple Myeloma, Hodgkin’s Disease and Non-Hodgkin’s Disease.
Bicnu 100 mg Injection contains Carmustine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis.
Bicnu 100 mg Injection may cause pulmonary toxicity, bone marrow suppression, gastrointestinal toxicity, nephrotoxicity and hepatotoxicity in some patients. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any side effects/interactions.
Bicnu 100 mg Injection is safe if taken at the prescribed dose and duration as advised by your doctor. It is effectively used in the treatment of brain tumours, multiple myeloma, Hodgkin's disease, and non-Hodgkin's disease. However, it may cause some side effects like nausea, vomiting, headache, pale skin, dizziness, stomach upset, tiredness, loss of balance, and pain at the site of injection while taking it.
Bicnu 100 mg Injection is typically classified as an irritant among chemotherapy drugs. However, when given in high doses, it can have stronger effects and be considered a vesicant.
Yes, Bicnu 100 mg Injection works by preventing DNA and RNA transcription which is essential for protein synthesis.
The common side effects of Bicnu 100 mg Injection may include nausea, vomiting, headache, pale skin, dizziness, stomach upset, tiredness, loss of balance, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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