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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Bicarb 25% Injection is used to treat Metabolic acidosis, severe diarrhoea, drug intoxication, and poisoning. It contains Sodium bicarbonate, an electrolyte replenisher and systemic alkaliser that reduces the acid in the blood. It also helps reduce the amount of acid in the body after a heart attack in patients who have too much potassium in their blood or too much acid.

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Manufacturer/Marketer :

Medi Life

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Bicarb 25% Injection

Bicarb 25% Injection is indicated in treating metabolic acidosis and other conditions requiring systemic alkalinisation. It is also used to increase urinary pH to increase the solubility of certain weak acids, in treatment of certain intoxications to decrease renal absorption of the drug, severe diarrhoea accompanied by loss of bicarbonate, and poisoning by salicylates or methyl alcohol. Bicarb 25% Injection may also be used to treat patients who have taken too many tricyclic antidepressants only after other resuscitation methods have been attempted.

Bicarb 25% Injection contains Sodium bicarbonate, which acts as an electrolyte replenisher and systemic alkaliser, reducing the acid in the blood. Bicarb 25% Injection helps reduce the amount of acid in the body after a heart attack in patients who have too much potassium in their blood or too much acid.

Bicarb 25% Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience specific common side effects, such as injection site reactions, irritability, muscle spasms, and low levels of potassium in the blood. You should talk to your doctor if the side effects persist or worsen.

Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding. Please consult your doctor if you have any concerns regarding the usage of Bicarb 25% Injection in children. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Bicarb 25% Injection

Treatment of Metabolic acidosis, severe diarrhoea, drug intoxication, and poisoning

Directions for Use

Bicarb 25% Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Bicarb 25% Injection is indicated in the treatment of metabolic acidosis caused due to diabetes, hepatitis, starvation, shock, cardiac arrest, renal insufficiency, severe dehydration, severe primary lactic acidosis, Addison’s disease or administration of acidic drugs and other conditions requiring systemic alkalinisation. It is also used to increase urinary pH to increase the solubility of certain weak acids, in treatment of certain intoxications to decrease renal absorption of the drug, severe diarrhoea accompanied by loss of bicarbonate, and poisoning by salicylates or methyl alcohol. Bicarb 25% Injection may also be used to treat patients who have taken too many tricyclic antidepressants only after other resuscitation methods have been attempted. Bicarb 25% Injection acts as an electrolyte replenisher and systemic alkaliser. Thereby reducing the acid in the blood. Bicarb 25% Injection helps reduce the amount of acid in the body after a heart attack in patients who have too much potassium in their blood or too much acid.

How Bicarb 25% Injection Works

Bicarb 25% Injection contains Sodium bicarbonate, which acts as an electrolyte replenisher and systemic alkaliser, reducing the acid in the blood. Bicarb 25% Injection helps reduce the amount of acid in the body after a heart attack in patients who have too much potassium in their blood or too much acid.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Bicarb 25% Injection

  • Injection site reactions
  • Irritability
  • Muscle spasms
  • Low levels of potassium in the blood

What if I have taken an overdose of Bicarb 25% Injection

Since Bicarb 25% Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Bicarb 25% Injection may cause irregular heartbeat, tiredness, mood changes, muscle weakness, muscle hypertonicity, slow breathing, and twitching and tetany may develop.

Drug Warnings

Do not take Bicarb 25% Injection if you are allergic to any of its components; if you have kidney failure, heart failure, high blood pressure, low blood calcium/potassium/chloride, high blood sodium/pH, kidney stones, fluid retention, or hypoventilation (breathing problems). Inform your doctor if you have congestive heart failure, oedema with sodium-retaining conditions, or renal insufficiency. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding.

Drug-Drug Interactions

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Sodium bicarbonateGefitinib
Severe
Sodium bicarbonateDolutegravir
Severe

Drug-Drug Interactions

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Sodium bicarbonateGefitinib
Severe
How does the drug interact with Bicarb 25% Injection:
Taking Bicarb 25% Injection with Gefitinib together can reduce the levels and treatment outcomes of Gefitinib.

How to manage the interaction:
Although taking Gefitinib and Bicarb 25% Injection together can cause an interaction, it can be taken if a doctor has suggested it. Contact your doctor if your symptoms do not improve. Do not stop using any medications without talking to a doctor.
Sodium bicarbonateDolutegravir
Severe
How does the drug interact with Bicarb 25% Injection:
Co-administration of Bicarb 25% Injection and Dolutegravir reduces the levels of Dolutegravir, resulting in reduced effectiveness.

How to manage the interaction:
Although taking Dolutegravir and Bicarb 25% Injection together can result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience symptoms like fever, chills, diarrhea, sore throat, muscle aches, red or inflamed skin, and pain or burning during urination, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Stay hydrated.
  • Avoid smoking and alcohol consumption. 
  • Maintain a healthy weight by regular exercising.
  • Include foods rich in nutrients and potassium.
  • Eat small, frequent meals slowly if you have diarrhoea.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Bicarb 25% Injection Substitute

Substitutes safety advice
  • Bicarb Injection 25 ml

    7.85per tablet
  • Sodium Bicarbonate 7.5% Injection 25 ml

    1.01per tablet
  • Lifecare Sodium Bicarbonate Injection

    1.57per tablet
  • Sodium Bicarbonate Injection 25 ml

    by AYUR

    1.01per tablet
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Alcohol

Consult your doctor

It is unknown if alcohol affects Bicarb 25% Injection. Please consult your doctor.

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Pregnancy

Caution

Bicarb 25% Injection belongs to pregnancy category C. Please inform your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Inform your doctor if you are breastfeeding; your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Consult your doctor

It is not known if Bicarb 25% Injection affects your ability to drive. however, drive or operate machinery only if you are alert.

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Liver

Caution

Inform your doctor if you have a liver impairment or any concerns before receiving Bicarb 25% Injection.

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Kidney

Caution

Inform your doctor if you have kidney impairment or any concerns. Bicarb 25% Injection is not recommended if you have conditions like kidney failure or kidney stones.

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Children

Caution

Please consult your doctor if you have any concerns regarding the usage of Bicarb 25% Injection in children. Rapid injection (10 mL/min) of hypertonic Sodium bicarbonate injection solutions in children below twoyears may cause hypernatremia (high sodium levels), a decrease in cerebrospinal fluid pressure and possible intracranial haemorrhage.

FAQs

Bicarb 25% Injection is used to treat Metabolic acidosis, severe diarrhoea, drug intoxication, and poisoning.
Bicarb 25% Injection acts as an electrolyte replenisher and systemic alkaliser. It reduces the acid in the blood.
Bicarb 25% Injection is used to treat metabolic acidosis caused due to diabetes, hepatitis, starvation, shock, cardiac arrest, renal insufficiency, severe dehydration, severe primary lactic acidosis, Addison’s disease or administration of acidic drugs. Metabolic acidosis is an electrolyte disorder characterised by an acid-base imbalance in the body.
Bicarb 25% Injection is indicated in severe diarrhoea, which is often accompanied by a significant loss of bicarbonate. Bicarb 25% Injection helps by compensating for the lost bicarbonate ions.
Bicarb 25% Injection is indicated for treating certain drug intoxication, such as barbiturates (in cases where barbiturate-protein complex dissociation is desired). Bicarb 25% Injection may also be used to treat patients who have taken too many tricyclic antidepressants only after other resuscitation methods have been attempted.
Bicarb 25% Injection is used in poisoning by methyl alcohol or salicylates and in haemolytic reactions that require the alkalinisation of urine to lower the nephrotoxicity of haemoglobin and its by-products.

Country of origin

INDIA

Manufacturer/Marketer address

3426-B,Second Floor Mahendra Park,Rani Bagh, Near Wine Shop, Pitampura, Delhi-110034, India
Other Info - BIC0046

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Keep Refrigerated. Do not freeze.

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