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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Alzirol 200mg Tablet is an antifungal medicine used in the treatment of fungal infections such as blastomycosis, coccidioidomycosis, paracoccidioidomycosis, and histoplasmosis (lung infection caused by Histoplasma fungus). This medicine works by inhibiting the growth and multiplication of fungal cells that are responsible for the growth of infection-causing fungi.
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Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Alzirol 200mg Tablet

Alzirol 200mg Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus). It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.

Alzirol 200mg Tablet contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Take Alzirol 200mg Tablet as prescribed. Your doctor will advise you on how often you need to take Alzirol 200mg Tablet based on your medical condition. Some people may experience headache, nausea, stomach pain, and diarrhoea. Most of these side effects of Alzirol 200mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Alzirol 200mg Tablet. Avoid breastfeeding while taking Alzirol 200mg Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption whilst on treatment with Alzirol 200mg Tablet. Alzirol 200mg Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that the benefits outweigh the risks.

Uses of Alzirol 200mg Tablet

Treatment of Systemic fungal infections

Medicinal Benefits

Alzirol 200mg Tablet is an antifungal used to treat severe fungal infections. It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks. It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Directions for Use

Take Alzirol 200mg Tablet with food to avoid stomach upset or take it as advised by the doctor. Swallow the whole tablet/capsule with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Alzirol 200mg Tablet

  • Headache
  • Nausea
  • Stomach pain
  • Diarrhoea 

Drug Warnings

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Alzirol 200mg Tablet. Avoid breastfeeding while taking Alzirol 200mg Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption with Alzirol 200mg Tablet. If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage). 

Drug Interactions

Drug-Drug Interaction: Alzirol 200mg Tablet may interact with antiarrhythmic agents (quinidine, dofetilide), antipsychotic drugs (pimozide), drugs used to treat heartburn and acidity (omeprazole, cisapride), cholesterol-lowering medicines (simvastatin, lovastatin), medicines used to treat migraine (dihydroergotamine, ergotamine), high blood pressure lowering drugs (nisoldipine, eplerenone) and benzodiazepines (alprazolam, triazolam, midazolam).

Drug-Food Interaction: Alzirol 200mg Tablet may interact with caffeine. Therefore, avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola, and energy drinks as it may increase the adverse effects of caffeine. Do not take marijuana with Alzirol 200mg Tablet as it may worsen the adverse effects of marijuana. Also, avoid consumption of alcohol with Alzirol 200mg Tablet as it may increase the risk of liver damage and cause adverse effects. 

Drug-Disease Interaction: If you have adrenal insufficiency, heart or liver problems, inform your doctor before taking Alzirol 200mg Tablet.

Drug-Drug Interactions Checker List

  • QUINIDINE
  • DOFETILIDE
  • PIMOZIDE
  • OMEPRAZOLE
  • CISAPRIDE
  • SIMVASTATIN
  • LOVASTATIN
  • DIHYDROERGOTAMINE
  • ERGOTAMINE
  • NISOLDIPINE
  • EPLERENONE
  • ALPRAZOLAM
  • TRIAZOLAM
  • MIDAZOLAM

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
  • Wear a respiratory mask when there is a risk of exposure to spores.
  • People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
  • Close windows and stay inside during dust storms.
  • Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.

Disease/Condition Glossary

Systemic fungal infections are fungal infections that affect internal organs. The fungus lives in the environment, particularly in moist soil and in decomposing organic matter such as leaves and wood. Fungi enter the body via the paranasal sinuses, gut, lungs, or skin, and may spread to other organs. If these infections are not treated with appropriate therapy or if treatment is delayed, it may lead to medical emergencies. The symptoms of systemic fungal infection in people with normal immune function include cough, fever, or loss of appetite. It can also affect people who are immune compromised.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Alzirol 200mg Tablet as it may increase the risk of liver damage and cause adverse effects.

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Pregnancy

Caution

Alzirol 200mg Tablet is a Category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Unsafe

Alzirol 200mg Tablet may be excreted in breast milk. Therefore, it is recommended to avoid breastfeeding while taking Alzirol 200mg Tablet.

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Driving

Caution

Alzirol 200mg Tablet may cause dizziness or drowsiness. Therefore, drive only if you alert after taking Alzirol 200mg Tablet.

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Liver

Unsafe

Alzirol 200mg Tablet is contraindicated in patients with chronic or acute liver disease. Therefore, inform your doctor if you have any Liver diseases/conditions.

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Kidney

Caution

If you have any concerns regarding the use of Alzirol 200mg Tablet in patients with kiver diseases/conditions, consult a doctor.

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Children

Caution

Alzirol 200mg Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that benefits outweigh risks.

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FAQs

Alzirol 200mg Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus).
Alzirol 200mg Tablet works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.
Alzirol 200mg Tablet is not recommended to treat fungal meningitis (fungal infection spreads to the brain and spinal cord) as it poorly penetrates into the cerebrospinal fluid. Therefore, inform your doctor if you have fungal meningitis so that appropriate medication may be prescribed.
You are recommended to avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola and energy drinks while taking Alzirol 200mg Tablet as it may increase the adverse effects of caffeine such as drowsiness, nervousness or nausea.
You are not recommended to take Alzirol 200mg Tablet with simvastatin (lipid-lowering drug) as co-administration of these medicines may cause muscle problems. Therefore, please consult a doctor before taking Alzirol 200mg Tablet with other medicines.
No, you are not recommended to stop taking Alzirol 200mg Tablet without consulting your doctor as it may cause recurring infection. Therefore, take Alzirol 200mg Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Alzirol 200mg Tablet, please consult your doctor.

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