Afatin 30 Tablet 28's
₹4100*
MRP ₹5000
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MRP ₹5000
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Afatin 30 Tablet 28's is an anti-cancer medicine used in the treatment of non-small cell lung cancer (NSCLC). It is a common form of lung cancer in which abnormal cells grow in the lung tissues. Afatin 30 Tablet 28's is used as a first-line therapy in the treatment of metastatic NSCLC with non-resistant epidermal growth factor receptor (EGFR) mutations and in patients with metastatic, squamous NSCLC progressing after platinum-based chemotherapy.
Afatin 30 Tablet 28's contains Afatinib as an active ingredient, which belongs to the class of medicines known as kinase inhibitors. It works by stopping the action of an enzyme (tyrosine kinase) that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.
Afatin 30 Tablet 28's may cause certain side effects such as diarrhea, rash, decreased appetite, nausea, vomiting, dry skin, mouth sores, nail inflammation, ache, cough, abdominal pain, and itching. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Afatin 30 Tablet 28's should be taken as advised by your doctor. Do not take more than the recommended dose. Your doctor will decide the dose of Afatin 30 Tablet 28's based on the severity of your condition.
Avoid taking Afatin 30 Tablet 28's if you are allergic to it or any other components of it. Before taking Afatin 30 Tablet 28's, inform your doctor if you have/had liver or kidney disease, eye problems, lung disease other than lung cancer, heart problems, and breathing difficulty. This medicine is known to cause embryo-fetal toxicity. It is not recommended for use in pregnancy and breastfeeding. Elderly people are more sensitive to medicine, so the dose may have to be adjusted according to their condition.
Afatin 30 Tablet 28's contains Afatinib, which belongs to the class of medicines known as kinase inhibitors. It works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. It also decreases the blood supply to cancer tumors to slow down the growth of the tumor. In this way, Afatin 30 Tablet 28's stops the body's production, spread and growth of cancerous cells.
To treat your condition effectually, continue taking Afatin 30 Tablet 28's for the period that your doctor has prescribed. Avoid taking Afatin 30 Tablet 28's if you are allergic to it or any other components present in it. Caution should be exercised if you have/had liver or kidney disease, eye problems, lung disease other than lung cancer, heart problems, severe cough, and breathing difficulty. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Afatin 30 Tablet 28's may cause severe diarrhea, Bullous and exfoliative skin disorder, hepatotoxicity, Interstitial lung disease, and keratitis in some patients. Hence, inform your doctor about your complete medication and medical history before taking Afatin 30 Tablet 28's. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. Avoid driving and operating machines, as this medicine may cause visual disturbances. This medicine is not recommended for use in children below 18 years of age as the safety and efficacy are not established.
Drug-Drug Interaction: Afatin 30 Tablet 28's may have interaction with P-gp (P-glycoprotein) inhibitors (amiodarone, clarithromycin, ciclosporin, colchicine, diltiazem, erythromycin, felodipine, ketoconazole), P-gp inducers (carbamazepine, rifampicin, phenytoin, ritonavir, phenobarbitone).
Drug-Food Interaction: Avoid alcohol consumption and smoking.
Dug-Disease Interaction: Tell your doctor if you have liver or kidney disease, vision problems, breathing problems, or heart problems.
Non-Small Cell Lung Cancer (NSCLC): Lung cancer is defined as an Uncontrollable growth of abnormal cells in one or both lungs. These abnormal cells do not carry out normal lung cell functions and do not develop into healthy lung tissue. There are different forms of lung cancer. The most common form of lung cancer is non-small cell lung cancer (NSCLC). It happens when cells that form the lining of the lung start growing uncontrollably. Cancerous cells of the lung spread off and travel through the bloodstream to distant regions of the body and grow. It is mostly seen in persons who smoke. Symptoms may include chest pain, weight loss, hoarseness, and difficulty breathing.
Alcohol
Caution
Limit alcohol consumption while taking Afatin 30 Tablet 28's.
Pregnancy
Unsafe
Afatin 30 Tablet 28's is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Afatin 30 Tablet 28's. You should not become pregnant while you are taking Afatin 30 Tablet 28's and for at least two weeks after your treatment. Using effective birth control methods while on treatment with Afatin 30 Tablet 28's is suggested.
Breast Feeding
Unsafe
Afatin 30 Tablet 28's should not be taken if you are breastfeeding as it passes into breast milk and may harm your infant.
Driving
Unsafe
Do not drive, operate machinery, or engage in any activity that needs clear vision until you are confident that you can do so safely while you are on treatment with Afatin 30 Tablet 28's.
Liver
Caution
If you have a pre-existing or a history of liver problems, tell your doctor before taking this medicine. Afatin 30 Tablet 28's is known to cause hepatotoxicity, which may be fatal. Hence, this medicine should be taken cautiously. Your doctor may suggest tests to monitor your liver function while on treatment with this medicine. Tell your doctor right away if you have any symptoms of a liver problem, which may include yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea-coloured) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, feeling very tired while taking Afatin 30 Tablet 28's.
Kidney
Caution
If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Afatin 30 Tablet 28's. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
Unsafe
Afatin 30 Tablet 28's is not recommended for children below 18 years as the safety and effectiveness were not established.
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