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Afanat 30 Tablet 28's

Afanat 30 Tablet 28's

Prescription drug
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Consult Doctor

Composition

AFATINIB-30MG

Manufacturer/Marketer

Natco Pharma Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Afanat 30 Tablet

Afanat 30 Tablet is an anti-cancer medicine used in the treatment of non-small cell lung cancer (NSCLC). It is a common form of lung cancer in which abnormal cells grow in the lung tissues. Afanat 30 Tablet is used as a first-line therapy in the treatment of metastatic NSCLC with non-resistant epidermal growth factor receptor (EGFR) mutations and in patients with metastatic, squamous NSCLC progressing after platinum-based chemotherapy.

Afanat 30 Tablet contains Afatinib as an active ingredient, which belongs to the class of medicines known as kinase inhibitors. It works by stopping the action of an enzyme (tyrosine kinase) that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body.

Afanat 30 Tablet may cause certain side effects such as diarrhea, rash, decreased appetite, nausea, vomiting, dry skin, mouth sores, nail inflammation, ache, cough, abdominal pain, and itching. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Afanat 30 Tablet should be taken as advised by your doctor. Do not take more than the recommended dose. Your doctor will decide the dose of Afanat 30 Tablet based on the severity of your condition.

Avoid taking Afanat 30 Tablet if you are allergic to it or any other components of it. Before taking Afanat 30 Tablet , inform your doctor if you have/had liver or kidney disease, eye problems, lung disease other than lung cancer, heart problems, and breathing difficulty. This medicine is known to cause embryo-fetal toxicity. It is not recommended for use in pregnancy and breastfeeding. Elderly people are more sensitive to medicine, so the dose may have to be adjusted according to their condition.

Uses of Afanat 30 Tablet

Treatment of Non-small cell lung cancer (NSCLC)

Medicinal Benefits

Afanat 30 Tablet contains Afatinib, which belongs to the class of medicines known as kinase inhibitors. It works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. It also decreases the blood supply to cancer tumors to slow down the growth of the tumor.  In this way, Afanat 30 Tablet stops the body's production, spread and growth of cancerous cells.

Directions for Use

Take Afanat 30 Tablet as prescribed by the doctor. It should be taken without food on an empty stomach at least one hour before or two hours after a meal. Swallow it as a whole with a glass of water. Do not crush, break, or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Afanat 30 Tablet

  • Acne
  • Dry skin
  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Itching or skin rash
  • Mouth sores
  • Cough
  • Nail inflammation
  • Visual disturbances
  • Abdominal pain

Drug Warnings

To treat your condition effectually, continue taking Afanat 30 Tablet for the period that your doctor has prescribed. Avoid taking Afanat 30 Tablet if you are allergic to it or any other components present in it. Caution should be exercised if you have/had liver or kidney disease, eye problems, lung disease other than lung cancer, heart problems, severe cough, and breathing difficulty. This medicine is known to cause embryo-fetal toxicity. Hence, inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment. Afanat 30 Tablet may cause severe diarrhea, Bullous and exfoliative skin disorder, hepatotoxicity, Interstitial lung disease, and keratitis in some patients. Hence, inform your doctor about your complete medication and medical history before taking Afanat 30 Tablet . Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. Avoid driving and operating machines, as this medicine may cause visual disturbances. This medicine is not recommended for use in children below 18 years of age as the safety and efficacy are not established.

Drug Interactions

Drug-Drug Interaction: Afanat 30 Tablet may have interaction with P-gp (P-glycoprotein) inhibitors (amiodarone, clarithromycin, ciclosporin, colchicine, diltiazem, erythromycin, felodipine, ketoconazole), P-gp inducers (carbamazepine, rifampicin, phenytoin, ritonavir, phenobarbitone).

Drug-Food Interaction: Avoid alcohol consumption and smoking.

Dug-Disease Interaction: Tell your doctor if you have liver or kidney disease, vision problems, breathing problems, or heart problems.

Drug-Drug Interactions Checker List

  • AMIODARONE
  • CICLOSPORIN
  • DILTIAZEM
  • FELODIPINE
  • CARBAMAZEPINE
  • RIFAMPICIN
  • PHENYTOIN

Habit Forming

No

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles, reduces fatigue, helps in weight loss, and gives strength. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, etc.
  • Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains, nuts, and seeds.
  • Avoid smoking and alcohol consumption.

Special Advise

  • Your doctor may suggest periodic liver function tests to monitor the function of the liver due to the use of Afanat 30 Tablet .
  • Avoid being under the sun for a long time, as prolonged duration of sun exposure may cause serious hypersensitivity reactions.

Disease/Condition Glossary

Non-Small Cell Lung Cancer (NSCLC): Lung cancer is defined as an Uncontrollable growth of abnormal cells in one or both lungs. These abnormal cells do not carry out normal lung cell functions and do not develop into healthy lung tissue. There are different forms of lung cancer. The most common form of lung cancer is non-small cell lung cancer (NSCLC). It happens when cells that form the lining of the lung start growing uncontrollably. Cancerous cells of the lung spread off and travel through the bloodstream to distant regions of the body and grow. It is mostly seen in persons who smoke. Symptoms may include chest pain, weight loss, hoarseness, and difficulty breathing.

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Alcohol

Caution

Limit alcohol consumption while taking Afanat 30 Tablet .

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Pregnancy

Unsafe

Afanat 30 Tablet is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Afanat 30 Tablet . You should not become pregnant while you are taking Afanat 30 Tablet and for at least two weeks after your treatment. Using effective birth control methods while on treatment with Afanat 30 Tablet is suggested.

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Breast Feeding

Unsafe

Afanat 30 Tablet should not be taken if you are breastfeeding as it passes into breast milk and may harm your infant.

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Driving

Unsafe

Do not drive, operate machinery, or engage in any activity that needs clear vision until you are confident that you can do so safely while you are on treatment with Afanat 30 Tablet .

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Liver

Caution

If you have a pre-existing or a history of liver problems, tell your doctor before taking this medicine. Afanat 30 Tablet is known to cause hepatotoxicity, which may be fatal. Hence, this medicine should be taken cautiously. Your doctor may suggest tests to monitor your liver function while on treatment with this medicine. Tell your doctor right away if you have any symptoms of a liver problem, which may include yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea-coloured) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, feeling very tired while taking Afanat 30 Tablet .

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Kidney

Caution

If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Afanat 30 Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Afanat 30 Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - AFA0007

FAQs

Afanat 30 Tablet is used to treat Non-small cell lung cancer (NSCLC).
Afanat 30 Tablet contains Afatinib, which works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells.
The most common sign of lung cancer is a cough that lasts long and gets worse with time. Sometimes, a patient may notice blood in the cough. Chest pain is also a sign of lung cancer, followed by coughing.
Afanat 30 Tablet is safe to be taken by a diabetic person. However, take Afanat 30 Tablet only after consulting with a doctor, as they may adjust the dosing according to your condition.

Disclaimer

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