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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:54 PM IST

Actipin 25mg Tablet is used to treat depression and anxiety when patients become intolerant to other medicines. In addition, it is also given as a medication to treat insomnia (difficulty in sleeping) in some people. It contains Doxepin, which increases the level of chemicals in the brain responsible for mood changes and causing depression. As a result, your mood is enhanced, and you feel better. If it is prescribed for insomnia, it helps us sleep for more time and treats sleeping difficulty. In some cases, you may experience side effects such as drowsiness, dry mouth, increased heart rate, constipation, weight gain, difficulty in urination, and sudden blood pressure lowering on standing up (orthostatic hypotension). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition

DOXEPIN-25MG

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Actipin 25mg Tablet

Actipin 25mg Tablet is used to treat depression and anxiety when patients become intolerant to other medicines. In addition, it is also given as a medication to treat insomnia (difficulty in sleeping) in some people. An anxiety disorder is a mental condition characterized by excessive fear or worry affecting an individual's daily activities. High anxiety levels can cause panic attacks, with intense feelings of nervousness, fear, sudden onset of sweating, hyperventilation, fast heartbeat, and skin flushing.

Actipin 25mg Tablet contains Doxepin, a tricyclic antidepressant that increases the level of chemicals in the brain known as GABA, responsible for mood changes and causing depression. As a result, your mood is enhanced, and you feel better. If Actipin 25mg Tablet is prescribed for insomnia, it helps us sleep for more time and treats sleeping difficulty.

Take Actipin 25mg Tablet as prescribed by your doctor. Depending upon your medical condition, you are advised to take Actipin 25mg Tablet for as long as your doctor has prescribed it for you. In some cases, you may experience drowsiness, dry mouth, increased heart rate, constipation, weight gain, difficulty in urination, and sudden blood pressure lowering on standing up (orthostatic hypotension). Most of these side effects of Actipin 25mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Actipin 25mg Tablet if you have had an allergic reaction to Actipin 25mg Tablet or any of its ingredients. Actipin 25mg Tablet should not be taken if you have glaucoma (increased eye pressure), severe liver or kidney problems, asthma, difficulty in urination, and have taken monoamine oxidase inhibitors (MAOs) in the last 15 days. If you are breastfeeding or pregnant, please do not take Actipin 25mg Tablet as it is a category C pregnancy drug. Actipin 25mg Tablet may lead to withdrawal symptoms if stopped abruptly, like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. So, please consult your doctor; the doctor might lower your dose depending on your medical condition.

Uses of Actipin 25mg Tablet

Treatment of Depression, Anxiety, Insomnia (sleepiness)

Medicinal Benefits

Actipin 25mg Tablet contains Doxepin, which is a tricyclic anti-depressant. It is primarily used to treat depression and anxiety when patients become intolerant to other medicines. In addition to this, it is also given as a medication to treat insomnia (difficulty in sleeping) in some people. Doxepin works by increasing the level of chemicals in the brain responsible for mood changes and causing depression. As a result, your mood is enhanced, and you feel better. If Actipin 25mg Tablet is prescribed for insomnia, it helps us sleep for more time and, hence, treats sleeping difficulty.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Actipin 25mg Tablet

  • Drowsiness
  • Dry mouth
  • Increased heart rate
  • Constipation
  • Weight gain
  • Difficulty in urination
  • Orthostatic hypotension (Sudden lowering of blood pressure on standing up)

Drug Warnings

Do not take Actipin 25mg Tablet if you have had an allergic reaction to any ingredient present in Actipin 25mg Tablet or if you have glaucoma (increased eye pressure), serious liver or kidney problem, asthma, difficulty in urination, and have taken monoamine oxidase inhibitors  (MAOIs) in the last 15 days. If you are breastfeeding or pregnant, please do not take Actipin 25mg Tablet as it is a category C pregnancy drug. Do not take alcohol and Actipin 25mg Tablet as it can affect you much more and make you even more depressed. Avoid driving or anything that requires concentration, as Actipin 25mg Tablet is known to cause drowsiness. Actipin 25mg Tablet may lead to withdrawal symptoms if stopped abruptly, like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. So, please consult your doctor; the doctor might lower your dose depending on your medical condition.

Drug Interactions

Drug-Drug Interactions: Actipin 25mg Tablet is known to interact with monoamine oxidase (MAO) inhibitors (e.g. isocarboxazid, phenelzine, selegiline, tranylcypromine), antipsychotics (e.g. chlorpromazine, fluphenazine, perphenazine, prochlorperazine, thioridazine, trifluoperazine, bupropion), medication to treat stomach ulcer (e.g. cimetidine), thyroid hormone, anti-diabetic medications (e.g. tolazamide), opioid pain or cough relievers (e.g. codeine, hydrocodone),  and drugs used for sleep or anxiety disorders (e.g. alprazolam, lorazepam, zolpidem).

Drug-Food Interactions: Actipin 25mg Tablet is known to interact with alcohol.

Drug-Disease Interactions: Actipin 25mg Tablet should not be given to patients with glaucoma (increased eye pressure), serious liver or kidney problem, difficulty in urination, asthma, or have taken monoamine oxidase inhibitors (MAOs) in the last 15 days.

Drug-Drug Interactions Checker List

  • ISOCARBOXAZID
  • PHENELZINE
  • SELEGILINE
  • TRANYLCYPROMINE
  • CHLORPROMAZINE
  • PROCHLORPERAZINE
  • THIORIDAZINE
  • TRIFLUOPERAZINE
  • BUPROPION
  • CIMETIDINE
  • THYROXINE
  • TOLAZAMIDE
  • PERPHENAZINE

Habit Forming

No

Diet & Lifestyle Advise

  • Regular exercise can help lower anxiety by releasing endorphins and improving your sleep and self-image.
  • Find humour in your daily life. Try to watch a comedy show to help relieve stress.
  • You can try increasing your mindfulness by including yoga, meditation, cognitive therapy, and mindfulness-based stress reduction.
  • Drink enough water to stay hydrated, and limit or avoid alcohol and caffeine to relieve anxiety.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating many simple carbohydrates in processed foods.
  • Herbs like turmeric, ginger, and chamomile contain anti-inflammatory properties. Including these in a meal can reduce inflammation caused by anxiety disorders.
  • Reduce your alcohol, caffeine, added sugar, salt, and fat intake. Transfat, especially, may help reduce inflammation.
  • Antioxidants, such as ashwagandha, omega-3 fatty acids, green tea, and lemon balm, can be included in your daily diet.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Special Advise

  • Regular blood tests are required to monitor blood sugar and sodium levels.
  • Regular blood tests are performed to monitor various kinds of blood cells.
  • Actipin 25mg Tablet may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors.

Disease/Condition Glossary

Anxiety: Anxiety disorders are different from feelings of anxiety and feeling nervous, which involve excessive anxiety, fear, or worry. Fear can arise due to anxiety and emotional response to an immediate threat related to more staying to fight or leaving to escape danger. Fear before getting ready for surgery is also a part of short-term anxiety. Anxiety disorders can affect an individual's job performance, school work, and personal relationships.

Depression: It is a mood disorder characterized by sadness, unhappiness, anger, hopelessness, or loss that interferes with a person's daily activities. Depression can also influence some chronic health conditions and relationships. The exact cause of depression is unknown, but it may be associated with mental problems, trauma, family history, drug use, and medical conditions.

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Alcohol

Unsafe

Actipin 25mg Tablet should not be taken along with alcohol as it can affect you much more and may make you feel more depressed.

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Pregnancy

Caution

Actipin 25mg Tablet is a pregnancy category C drug. It is not known whether it will harm the baby or not. So, it should be only taken when prescribed by a doctor.

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Breast Feeding

Unsafe

Actipin 25mg Tablet is not recommended for breastfeeding women.

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Driving

Unsafe

Actipin 25mg Tablet may impair your concentration and lead to drowsiness, so do not drive after taking Actipin 25mg Tablet.

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Liver

Caution

Inform your doctor before receiving the Actipin 25mg Tablet if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current liver conditions.

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Kidney

Caution

Inform your doctor before receiving the Actipin 25mg Tablet if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current liver conditions.

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Children

Caution

Actipin 25mg Tablet is not recommended for children below the age of 12 years.

Country of origin

India
Other Info - AC83527

Author Details

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FAQs

Actipin 25mg Tablet is used to treat depression and anxiety when patients become intolerant to other medicines. In addition, it is also used to treat insomnia (difficulty in sleeping) in some people.
Actipin 25mg Tablet contains Doxepin, which is a tricyclic anti-depressant. Doxepin works by increasing the level of chemicals in the brain responsible for mood changes and causing depression. As a result, your mood is enhanced, and you feel better. If Actipin 25mg Tablet is prescribed for insomnia, it helps us to sleep for more time and hence treats difficulty in sleeping.
The time of taking the Actipin 25mg Tablet depends upon the medical condition for which you are taking it. If you are taking it for insomnia, take it 30 minutes before your bedtime. If you are taking it for anxiety or depression, take it as advised by your doctor for the best results. Also, take medicine at the same time each day.
Actipin 25mg Tablet can cause weight gain but in a sporadic case. If you feel you are gaining weight, please inform your doctor and do as advised.
NO, Actipin 25mg Tablet should not be stopped abruptly, even if you feel better. It may lead to withdrawal symptoms like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. So, please consult your doctor; the doctor might lower your dose depending on your medical condition.
If you have allergies to any of its ingredients or are pregnant, you are advised to avoid using Actipin 25mg Tablet. Do not take the Actipin 25mg Tablet if you have glaucoma (increased eye pressure), severe liver or kidney issues, or trouble urinating. Take Actipin 25mg Tablet only as recommended by a doctor and with under medical care if you are pregnant or nursing. If you have taken an MAO inhibitor within the last 15 days, avoid taking Actipin 25mg Tablet.
Yes, Actipin 25mg Tablet can be used to treat insomnia, especially in people who do not fall asleep or have difficulty staying asleep.
Actipin 25mg Tablet contains Doxepin, which is a tricyclic antidepressant medication. It works by increasing the levels of certain chemicals in the brain called GABA (Gamma-aminobutyric acid). These chemicals help regulate mood and can reduce feelings of depression. If Actipin 25mg Tablet is prescribed for insomnia, it can help you sleep longer and improve sleep quality.
Actipin 25mg Tablet may lead to withdrawal symptoms if stopped abruptly, like suicidal thoughts, irritability, and excessive aggression, which can sometimes be fatal. So, please consult your doctor; they may recommend gradually reducing your dose rather than stopping it all at once, depending on your medical condition.
Actipin 25mg Tablet should not be taken if you are allergic to any of its ingredients, or if you have used monoamine oxidase inhibitor (MAOI) within the past 15 days (a class of drugs used to treat depression and other neurological disorders). Also, do not take Actipin 25mg Tablet if you have glaucoma (increased eye pressure), severe liver or kidney problems, asthma, or difficulty urinating.
No, do not drive while taking Actipin 25mg Tablet, as it may cause drowsiness and impair your concentration. If you feel sleepy or dizzy, avoid driving until you are sure it is safe.
Overdose symptoms of Actipin 25mg Tablet can include irregular heartbeat, feeling agitated or confused, drowsiness, trouble concentrating, vomiting, seizures, muscle stiffness, increase in pupil size, hallucination (seeing or hearing things that aren't there), fever, low body temperature, and even coma (loss of consciousness for some time). If you suspect an overdose, seek immediate medical help from your doctor.
It usually takes several weeks or longer for you to experience the full effects of Actipin 25mg Tablet. Even if you start feeling better, it is important to continue taking Actipin 25mg Tablet as prescribed. Do not stop taking Actipin 25mg Tablet abruptly without consulting your doctor, the doctor will reduce your dose gradually to prevent withdrawal symptoms.
No, do not drink alcohol while taking Actipin 25mg Tablet, as alcohol may increase the side effects of the medication.
No, Actipin 25mg Tablet is generally not considered addictive. While it may cause withdrawal symptoms if stopped suddenly, Actipin 25mg Tablet has not been found to cause the psychological dependence commonly associated with addictive substances.
Yes, Actipin 25mg Tablet, like other antidepressants, may increase the risk of suicidal thoughts or behaviours, particularly in children, adolescents, and young adults. This risk is higher when starting the medication or adjusting the dosage. If you notice any changes in your mental health while using Actipin 25mg Tablet, please contact your doctor immediately.
The common side effects of Actipin 25mg Tablet include drowsiness, dry mouth, increased heart rate, constipation, weight gain, difficulty urinating, and a sudden drop in blood pressure upon standing (orthostatic hypotension). Most of these side effects may resolve gradually over time, but if they persist or worsen, please consult your doctor.

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