Zyris Nasal Spray is primarily used to treat nasal congestion (stuffy nose). It is also used to treat stuffy noses caused by sinus irritation, allergies, and the common cold. Nasal congestion is the blockage of nasal passage due to stuffed-up nasal fluid in the nose.

Zyris Nasal Spray contain Xylometazoline. Xylometazoline belongs to the class of 'decongestants'. It works by easing the inflammation and blocking of nasal passages by narrowing the blood vessels (vasoconstriction) and thus provides temporary relief from nasal congestion and blockage.

Take Zyris Nasal Spray as recommended by your physician. You are advised to take Zyris Nasal Spray for as long as your physician has suggested it for you, depending on your medical conditions. You may experience a burning sensation, dry nose, and sneezing. Most of these side effects of Zyris Nasal Spray do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your physician.

Do not take Zyris Nasal Spray if you are allergic to Xylometazoline. Tell your physician if you are pregnant or breastfeeding. Inform your physician if you have high blood pressure, diabetes, glaucoma (increased eye pressure), liver disease, kidney disease, and thyroid disorder. Zyris Nasal Spray does not produce any effect on the ability to drive. Zyris Nasal Spray is not recommended for the use of children less than 12 years of age.

Zyris Nasal Spray treats nasal congestion or blocked nose in common cold, sinusitis, hay fever, perennial and allergic rhinitis. It consists of Xylometazoline. Xylometazoline is a decongestant and an antihistamine drug. It works by easing the inflammation and blocking of nasal passages by narrowing the blood vessels (vasoconstriction) and reduces the swelling. This process provides temporary relief from nasal congestion and blockage. As an antihistamine drug, Xylometazoline provides relief from runny nose and sneezing by blocking the action of allergy-causing histamines.

• Burning sensation
• Stinging
• Headache
• Increased blood pressure
• Dryness in the nose
• Dry mouth
• Increased heart rate
• Runny nose
• Sneezing 

Please inform your physician if you use any other medicines, including vitamin and herbal supplements, before using Zyris Nasal Spray. Zyris Nasal Spray should be used only when advised by physician in people with a recent history of nasal surgery, chronic nasal inflammation, glaucoma, and adrenal gland tumors (phaeochromocytoma). Zyris Nasal Spray should be cautiously used in patients with heart, liver, or kidney diseases, inflammation of air passages, thyroid disorders (hyperthyroidism or overactive thyroid), enlarged prostate, urination problems, high blood pressure, and diabetes. Pregnant and breastfeeding women should use Zyris Nasal Spray with proper consultation and caution. Avoid consuming alcohol along with Zyris Nasal Spray to prevent any unwanted side effects. Zyris Nasal Spray is not recommended for use in children below 12 years of age, unless recommended by a child specialist.

Drug-Drug Interactions: Zyris Nasal Spray may interact with antidepressants (amitriptyline, isocarboxazid, phenelzine, selegiline, tranylcypromine, moclobemide), antibiotics (linezolid), drugs to treat Parkinson's disease (rasagiline, safinamide), blood pressure medicines (guanethidine).

Drug-Food Interactions: Avoid cold foods and drinks to ease your nasal congestion.

Drug-Disease Interactions: Zyris Nasal Spray should not be used in patients with glaucoma (an eye problem), high blood pressure, diabetes, and thyroid disorder.

• AMITRIPTYLINE
• ISOCARBOXAZID
• PHENELZINE
• SELEGILINE
• TRANYLCYPROMINE
• MOCLOBEMIDE
• RASAGILINE
• SAFINAMIDE
• GUANETHIDINE
• LINEZOLID

• Know your triggers like allergens, such as pollen, dust, and food items that make your asthma and other respiratory diseases severe.
• Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
• Drink extra fluids while you take Zyris Nasal Spray to help loosen congestion and lubricate the throat.
• Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
• Learning breathing exercises will help you move more air in and out of your lungs.

If you do not notice any improvement in your condition after using Zyris Nasal Spray for 5-7 days, please reach out to your physician.

Allergic rhinitis: It is an inflammation and allergy of the nose caused by an allergen, such as pollen, dust, mold, or flakes of skin from certain animals. Its symptoms include itchy, watery eyes, an itchy nose, sneezing, and a runny nose. 

Sinusitis is termed as inflammation of cavities around nasal passages, known as sinuses. It can be acute and chronic. Cold and other allergic factors can trigger acute sinusitis. Chronic sinusitis is caused due to an infection or growth in the sinuses (nasal polyps). Symptoms of sinusitis include headache, facial pain, runny nose, and nasal congestion.