Ursoden-SL Tablet belongs to a group of medicines called the biliary agent or gall stone dissolution agents used to treat primary biliary cirrhosis and gall stones. Primary biliary cholangitis, formerly known as primary biliary cirrhosis, is an autoimmune disease caused by damage of bile ducts in the liver. Biliary cirrhosis causes a build-up of bile in the liver, which leads to liver damage.  
Ursoden-SL Tablet is a combination of two drugs, namely: Ursodeoxycholic acid and Silymarin. Ursodeoxycholic acid helps in decreasing the production of cholesterol in the blood, thereby dissolving gall bladder stones. Silymarin has immunomodulatory, antioxidant and anti-fibrotic properties. Ursoden-SL Tablet has a protective effect on the liver cells and the immune system, thereby helps in improving liver function.
 
You are advised to take Ursoden-SL Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as abdominal discomfort, diarrhoea, nausea, rash, dizziness, indigestion, and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Do not discontinue Ursoden-SL Tablet without consulting your doctor. To treat your condition effectually, continue taking Ursoden-SL Tablet for as long as prescribed. Consult your doctor before taking Ursoden-SL Tablet if you are pregnant or breastfeeding. Ursoden-SL Tablet should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with Ursoden-SL Tablet as it could lead to liver damage. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Ursoden-SL Tablet belongs to a group of medicines called the biliary agent or gall stone dissolution agents used to treat gall stones, primary biliary cholangitis (an autoimmune disease of the liver), and excess cholesterol in bile. Ursoden-SL Tablet contains ursodeoxycholic acid and silymarin. Ursodeoxycholic acid is a naturally occurring bile acid that breaks down the cholesterol formed into gall bladder stones, thereby dissolving the stones. Silymarin has immunomodulatory, antioxidant and anti-fibrotic properties. Ursoden-SL Tablet has a protective effect on the liver cells and the immune system, thereby helps in improving liver function. Ursoden-SL Tablet decreases the amount of cholesterol produced by the liver and absorbed by the intestine. In patients with primary biliary cirrhosis, Ursoden-SL Tablet increases the bile flow.

• Abdominal discomfort
• Diarrhoea
• Nausea
• Rash
• Dizziness
• Indigestion
• Weakness

Do not take Ursoden-SL Tablet if you are allergic to any of its components; if you have inflammation of gall bladder and bile ducts, narrowing or blockage of bile ducts, biliary colic, calcified gallstones, improper constriction of the gallbladder, gastric or duodenal ulcer. Inform your doctor before taking Ursoden-SL Tablet if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease. Consult your doctor before taking Ursoden-SL Tablet if you are pregnant or breastfeeding. Ursoden-SL Tablet should be given to children only if prescribed by the doctor. Avoid consuming alcohol with Ursoden-SL Tablet as it could lead to increased liver damage. Keep your doctor informed about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions: Ursoden-SL Tablet may interact with antibiotics (ciprofloxacin and dapsone), antihypertensive agents (nitrendipine), immunosuppressants (cyclosporine), hormone (oestrogen), antacids (aluminium hydroxide, aluminium carbonate, magaldrate).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have biliary obstruction or liver impairment.

• CIPROFLOXACIN
• DAPSONE
• NITRENDIPINE
• CYCLOSPORINE
• ESTROGEN
• ALUMINIUM HYDROXIDE
• ALUMINUM CARBONATE
• MAGALDRATE

• Include foods such as bell peppers, citrus fruits, leafy vegetables, tomatoes, milk, fish, low-fat dairy, beans, nuts, lentils, tofu and tempeh in your diet.
• Eat a healthy, well-balanced diet that includes fruits and vegetables.
• Foods rich in Vitamin B, C and calcium, are good for the gallbladder.
• Plant-based protein foods such as beans, nuts, lentils, tofu and tempeh help prevent gallbladder disease.
• Avoid high-fat, trans-fat, and processed foods.
• White bread, white pasta and sugars should be avoided.
• Avoid tobacco and alcohol consumption.

Primary biliary cholangitis: Primary biliary cholangitis, formerly known as primary biliary cirrhosis, is an autoimmune disease caused by damage of bile ducts in the liver. Bile ducts are the small channels that carry the bile (digestive fluid) from the liver to the small intestine, where it breaks down fats and aids in its absorption. Biliary cirrhosis causes a build-up of bile in the liver, which leads to liver damage.  

Gallbladder stones: The gallbladder is a small organ located below the liver that stores bile, a liquid that helps with digestion. Excess cholesterol in bile leads to the formation of gallstones. Gallstones can cause pain in the abdomen, dark urine and stools, indigestion, diarrhoea, nausea, and vomiting.