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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Last Updated Oct 9, 2024 | 12:37 PM IST
Trinerve Capsule is a combination medicine used to manage neuropathic pain, and nutritional deficiencies. This medicine works by altering the nerve signals that cause pain and thereby protects nerve fibres. It helps provide a protective effect on the nerve tissues and the brain. You may experience common side effects like nausea, vomiting, diarrhoea, stomach upset, dizziness, and rash.
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About Trinerve Capsule

Trinerve Capsule is used to treat neuropathic pain and nutritional deficiencies. It effectively treats various conditions caused by a lack of vitamins, such as vitamin B6 and B12 deficiencies, diabetic neuropathy (nerve damage due to diabetes), and peripheral neuropathy (nerve damage in the hands and feet). Nutritional deficiency occurs when the body is unable to absorb or get enough nutrients from food.

Trinerve Capsule contains Alpha lipoic acid, Gamma-Linolenic acid, Pyridoxine Hydrochloride, Methylcobalamin, and Chromium. Alpha-lipoic acid is an antioxidant that prevents cell damage and restores vitamin levels in the body. Gamma-Linolenic acid helps nourish and protect the body from damage caused by free radicals. Pyridoxine (vitamin B6) is involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters. Methylcobalamin (Mecobalamin/vitamin B12) regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Chromium helps control blood sugar levels in diabetes and thus prevents nerve damage due to increased blood sugar.

Your doctor will decide the dosage based on your medical condition. Sometimes, Trinerve Capsule may have common side effects like nausea, vomiting, diarrhoea, and headache. These side effects do not require medical attention and gradually resolve over time. 

Let your doctor know if you use any other medications, including vitamins, before starting Trinerve Capsule . Please tell your doctor if you are allergic to Trinerve Capsule or its components. It is essential to let your doctor know if you are pregnant, planning to conceive, or are a breastfeeding mother. Avoid consuming alcohol along with Trinerve Capsule to ensure maximum absorption of nutrients. Trinerve Capsule should be used in children only with the doctor's advice.

Uses of Trinerve Capsule

Treatment of Nutritional deficiencies and neuropathy

Medicinal Benefits

Trinerve Capsule contains Alpha lipoic acid, Gamma-Linolenic acid, Pyridoxine Hydrochloride, Methylcobalamin, and Chromium. Alpha-lipoic acid is an antioxidant that prevents cell damage and also decreases pain and numbness in neuropathy. Gamma-Linolenic acid helps nourish and protect the body from damage caused by the free radicals. It fights cell damage and reduces inflammation. Pyridoxine treats and prevents vitamin B6 deficiency, peripheral neuropathy, and seizures (fits). It is involved in the creation of red blood cells and neurotransmitters. Methylcobalamin regulates body functions and helps rejuvenate and protect damaged nerve cells by producing a substance called myelin. Chromium helps control blood sugar levels in diabetes and thus prevents nerve damage due to increased blood sugar.

Directions for Use

Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trinerve Capsule

  • Nausea
  • Vomiting
  • Headache
  • Diarrhoea

Drug Warnings

Let your doctor know if you have any heart, liver, or kidney diseases before starting Trinerve Capsule . This supplement should be used during pregnancy only when advised by your doctor. Pyridoxine is excreted into breast milk. Hence, breastfeeding women should consult their doctor before taking Trinerve Capsule . Drinking alcohol may hinder nutrient absorption; therefore, it is advised to limit alcohol intake while using Trinerve Capsule . Trinerve Capsule should be used in children only when advised by the doctor. Keep Trinerve Capsule away from direct sunlight. Do not store Trinerve Capsule above 25ºC.

Drug Interactions

Drug-Drug Interaction: Trinerve Capsule may interact with antitumor medicines, anti-cancer drugs (altretamine), blood thinners (aspirin, clopidogrel, enoxaparin, heparin), antipsychotic drugs (chlorpromazine, fluphenazine), and fits medicines (phenytoin).

Drug-Food Interaction: Please avoid alcohol while using Trinerve Capsule to ensure maximum absorption of nutrients.

Drug-Disease Interaction: Use Trinerve Capsule with medical advice if you have malabsorption syndrome (difficulty absorbing nutrition from food), liver, kidney, or heart diseases, and allergic reactions to medicines.

Drug-Drug Interactions Checker List

  • ALTRETAMINE
  • ASPIRIN
  • CLOPIDOGREL
  • ENOXAPARIN
  • HEPARIN
  • CHLORPROMAZINE
  • FLUPHENAZINE
  • PHENYTOIN

Habit Forming

No

Diet & Lifestyle Advise

  • Try Vitamin B complex food sources like milk, cheese, eggs, liver and kidney, chicken, red meat, tuna, mackerel, and salmon, shellfish, oysters, clams, dark green vegetables, such as spinach and kale, beets, avocados, potatoes, whole grains, cereals, kidney beans, black beans, and chickpea.

  • Taking vegetables like acorn squash, asparagus, beet greens, Brussels sprouts, and spinach can help you cope with Vitamin B deficiency.
  • Sprinkle sunflower seeds over your food, vegetables and salads. 
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water. Avoid smoking and alcohol consumption.
  • Exercise regularly and maintain a healthy lifestyle. Avoid excess fatty foods.

Special Advise

Let your doctor and the laboratory staff know if you are using Trinerve Capsule since Pyridoxine may interfere with a urine test for urobilinogen. 

Disease/Condition Glossary

Nutritional deficiency: A nutritional deficiency occurs when the body does not absorb or get enough nutrients from food. This condition occurs when a person's nutrient intake is less than the body's recommended requirement. It can lead to various health problems like a weak immune system, skin problems, digestion problems, defective bone growth, and neurological diseases.

Neuropathic pain: It is a nervous system disorder caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, such as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Symptoms include spontaneous, un-triggered pain, unpleasant feeling, shooting, burning or stabbing pain, and evoked pain.

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Alcohol

Caution

Avoid consuming alcohol along with Trinerve Capsule to ensure maximum absorption of nutrients.

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Pregnancy

Caution

Trinerve Capsule should be used during pregnancy only when advised by your doctor. Let your doctor know if you are pregnant or planning to conceive before taking Trinerve Capsule .

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Breast Feeding

Caution

Pyridoxine is excreted into breast milk. Please consult your doctor before taking Trinerve Capsule if you are a breastfeeding mother.

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Driving

Safe

Trinerve Capsule does not interfere with your driving abilities.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Trinerve Capsule . Your dosage may be adjusted in case of liver impairment.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Trinerve Capsule . Your dosage may be adjusted in case of renal impairment.

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Children

Caution

Trinerve Capsule should be given to children only when the doctor advises. The doctor will decide the dosage of Trinerve Capsule based on the child's age and weight.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - TRI0027

Author Details

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FAQs

Trinerve Capsule is used to treat Nutritional deficiencies and neuropathy.
Trinerve Capsule is a nutritional supplement that consists of Alpha-lipoic acid, Gamma-Linolenic acid, Pyridoxine Hydrochloride, Methylcobalamin, and Chromium. These constituents help reduce nerve pain and nerve damage in neuropathy. It works by improving blood circulation to peripheral body parts and thus relieving pain.
Pyridoxine may interfere with a urine test for urobilinogen. Please make sure your doctor and the laboratory staff know that you take Trinerve Capsule before undergoing blood and urine examinations.
Antacids may interfere with the absorption of Trinerve Capsule . Hence it is advised to take Trinerve Capsule two hours before or four hours after taking antacids.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

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