Systaflam Spray is a combination medicine used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, and low back pain. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure, or injury to the bones, joints, tendons, muscles, and ligaments. Osteoarthritis is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage.

Systaflam Spray combines five medicines: Diclofenac, Mephenesin, Menthol, Turpentine oil and Methyl salicylate. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that blocks the release of certain chemical messengers in the brain, which are responsible for causing pain and symptoms of inflammation, redness, and swelling. Mephenesin is a muscle relaxant (that relaxes the muscle and treats muscle pain). It works on the brain and spinal cord centres to relieve muscle hardness or spasms and improve the pain and movement of muscles. Methyl salicylate and Menthol are topical analgesics (applied directly to alleviate pain). They work initially by cooling the skin, followed by warming it up. This action helps improve blood circulation and relieve pain. Turpentine Oil is a lubricant.

Systaflam Spray is for external use only. Avoid getting the Systaflam Spray in contact with your eyes, nose or mouth. Do not apply it to wounded or damaged skin. In case of accidental contact, immediately rinse it with cold water. Like all medicines, Systaflam Spray can cause side effects, although not everybody gets them. You might experience side effects such as a burning sensation, irritation, itching and redness at the application site. Most of these side effects of Systaflam Spray do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use this medicine without consulting your doctor. Even though drugs used topically (directly applied) on the skin are not normally affected by any other medication, you should inform your doctor if you are taking any other medicine. Also, inform your doctor if you have had an allergic reaction to diclofenac or any other drugs in the past, any cut or infected skin and ever had signs of any lung, liver, kidney-related diseases/disorders, muscle weakness (myasthenia gravis), sleeping disorder or difficulty in sleeping (sleep apnoea). Please tell your doctor if you are pregnant or breastfeeding to avoid unnecessary risks.

Systaflam Spray combines five medicines: Diclofenac, Mephenesin, Menthol, Turpentine oil, and Methyl salicylate. Here, diclofenac works by blocking the release of certain chemical messengers in the brain that are responsible for causing pain and signs of inflammation such as redness and swelling. Mephenesin is a muscle relaxant (that relaxes the muscle and treats muscle pain). It works on the brain and spinal cord centres to relieve muscle hardness or spasms and improve the pain and movement of muscles. On the other hand, methyl salicylate and menthol work by causing the skin to feel cool and warm. This action helps improve blood circulation and thus provides relief from pain. Turpentine Oil is a lubricant.

• Burning
• Irritation
• Itching
• Redness

Consumption of alcohol should be avoided during the treatment with Systaflam Spray as it may lead to an increased risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure, high blood pressure and liver or kidney disease should not take Systaflam Spray. Besides this, it should be avoided during the last trimester of pregnancy unless the doctor has prescribed it. If you have a severe allergy to painkillers and have conditions like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Systaflam Spray.

Drug-Drug Interactions: Systaflam Spray may interact with muscle relaxants (Methadone, opioid), blood thinners (warfarin, aspirin), diuretics (furosemide and thiazide), and heart-related medicine (digoxin) interact with Systaflam Spray. If you are taking these medicines, make sure you contact the doctor before taking Systaflam Spray.

Drug-Food Interactions: No interaction found.

Drug-Disease Interactions: People with peptic ulcer, gastric bleeding, severe heart failure and high blood pressure should avoid intake of Systaflam Spray as it may lead to unpleasant side effects.

• METHADONE
• WARFARIN
• ASPIRIN
• FUROSEMIDE
• DIGOXIN

• Include more glucosamine, chondroitin sulfate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
• Please do not go for heavy exercise, as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, biking, and swimming. You can also strengthen your muscle strength by lifting light weights.
• In chronic conditions of arthritis or joint pain, fish like salmon, trout, tuna, and sardines are also used. These fish are enriched with omega-3 fatty acids and contain a minimum of chemicals called cytokines, which ramp up inflammation.
• Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel to minimise pain at the back of your curve. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

• Caution should be exercised, and it is advisable to consult a doctor before using it. “Nonsteroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke.
• Systaflam Spray should not be applied to cut or open skin wounds for pain relief.

Musculoskeletal pain: Musculoskeletal pain affects the bones, muscles, ligaments, tendons, and nerves. It can be acute or chronic and can be localized or widespread. The pain can be mild or severe enough to interfere with your daily routine. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure, or injury to the bones, joints, tendons, muscles, and ligaments. Musculoskeletal pain symptoms include stiffness, swelling, redness, weakness, muscle spasms or twitching, trouble moving the affected area, soreness, cracking, or popping sounds at the joints.

Osteoarthritis: Osteoarthritis is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation, and tenderness.