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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:18 PM IST
Stofine 0.25% Cream is used to treat fungal nail infections. It contains Amorolfine, which works by stopping the production of a chemical called ergosterol in fungi that causes nail infection. Without ergosterol, the fungus cannot survive. As a result, it kills infection-causing fungi. It may cause common side effects such as dry skin, itching, redness, or burning sensation of the skin. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Synonym

AMOROLFINE HYDROCHLORIDE

Manufacturer/Marketer

Proto Care

Consume Type

TOPICAL

Return Policy

Not Returnable

Expires on or after

Jan-27

About Stofine 0.25% Cream

Stofine 0.25% Cream belongs to a class of drugs called 'antifungal' primarily used to treat fungal nail infections. Fungal infection occurs when a fungus invades and affects the tissue on the skin.  Symptoms of a fungal infection include skin rash, irritation, redness, and scaling of the skin.  

Stofine 0.25% Cream contains 'Amorolfine' that works by stopping producing a chemical called 'ergosterol' in fungi that causes nail infection. Without ergosterol, the fungus cannot survive. As a result, infection-causing fungi die. 

Use Stofine 0.25% Cream as suggested by your doctor. Common side effects of Stofine 0.25% Cream may include dry skin, itching, redness, or burning sensation of the skin. Most of these side effects of Stofine 0.25% Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or a nursing mother, it is advised to consult a doctor before using Stofine 0.25% Cream. If you use Stofine 0.25% Cream in topical form, avoid smoking or going near naked flames as Stofine 0.25% Cream catches fire and burns easily. If you are using any steroidal cream, lotion or ointment, inform your doctor before taking Stofine 0.25% Cream to adjust the dose.

Uses of Stofine 0.25% Cream

Treatment of Fungal nail infection.

Medicinal Benefits

Stofine 0.25% Cream is an antifungal that is primarily used to treat fungal infections of nails and skin such as ringworm, jock itch and athlete’s foot, seborrheic dermatitis (dry, flaky skin on face, scalp, chest, upper back, or ears) and pityriasis (a type of skin rash that causes scaly, discoloured patches on chest, back, legs and arms). The fungal cell membranes are essential for their survival as they prevent unwanted substances into the cells and stop the leakage of cell contents. Stofine 0.25% Cream causes holes in the fungal cell membranes and kills fungi. Thereby, clears fungal infection and provides relief from cracking, burning, scaling and itching of the skin caused due to infections. 

Directions for Use

Avoid contact of Stofine 0.25% Cream with nose, mouth, or eyes. In case if it comes in contact with these areas accidentally, rinse with water thoroughly.Cream/Gel/Lotion: Wash and dry the infected area of the skin. Take a small amount on the finger and gently rub it on the clean and dry affected area and surrounding skin.Nail lacquer: File the infected area of the nail. Then gently clean the surface of the nail. Take some lacquer from the bottle with the help of the spatula. Apply the medicine over the entire surface of the nail. Again clean the spatula and keep it for reuse.Spray: Please read the instructions leaflet provided with the pack. Use the spray as suggested by the doctor.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Stofine 0.25% Cream

  • Itching

  • Dry skin

  • Redness

  • Burning sensation of the skin

Drug Warnings

Before using Stofine 0.25% Cream, let your doctor know if you have a history of liver diseases, adrenal gland problems, cataract, glaucoma, diabetes or allergic reactions to any medicine ingredient. Let your doctor know if you plan to become pregnant or already pregnant and a lactating mother. Studies show that there may be harmful effects on the baby; hence Stofine 0.25% Cream should be used with caution in pregnancy under your doctor's supervision. If you apply Stofine 0.25% Cream to breasts or nipple for treatment, wash it off while nursing your baby. Stofine 0.25% Cream is for external use only, so avoid contact with the eyes, the mouth, or intravaginally. Notify the doctor if there is no improvement after one week of treatment for tinea cruris or tinea corporis or two weeks for tinea pedis. When using Stofine 0.25% Cream in the groin area, patients should use the medication for two weeks only. Prolonged use of Stofine 0.25% Cream may cause hormonal suppression, Cushing's syndrome, hyperglycemia (increased blood sugar level), and glucosuria (high sugar in urine) in some patients. Apply sunscreen (SPF 30 or higher) whenever you go outdoor in the sunlight. 

Drug Interactions

Drug-Drug Interaction: Stofine 0.25% Cream may interact with respiratory-related medicines (budesonide, formoterol), drugs treating HIV/AIDS (ritonavir, cobicistat) and corticosteroids.

Drug-Food Interaction: No drug-food interactions found/established.

Drug-Disease Interaction: Stofine 0.25% Cream should not be given in patients with a history of allergic reactions to clotrimazole and betamethasone, have diabetes, liver diseases, cataract, glaucoma, adrenal gland problems, and hormonal problems.

Drug-Drug Interactions Checker List

  • BUDESONIDE
  • FORMOTEROL
  • COBICISTAT
  • RITONAVIR

Habit Forming

No

Diet & Lifestyle Advise

  • Always wear loose-fitting clothes to avoid further sweat and spread of the fungal infection.

  • In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.

  • Do not walk barefoot at places like gym showers to prevent fungal infections.

  • Do not scratch the affected area of skin as it can spread the infection to other body parts.

  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.

  • Wash your bedsheets and towels regularly.

  • Follow a candida diet if you suffer from vaginal yeast infection. Candida diet excludes high sugary foods, some dairy products and foods with artificial preservatives.

  • Avoid or limit the intake of alcohol and caffeine.

Special Advise

It is advised to reach out to your doctor if the fungal infection symptoms persist or worsen after two treatment weeks. Before applying Stofine 0.25% Cream, clean and dry the affected area. Avoid contact of Stofine 0.25% Cream with nose, mouth or eyes. If Stofine 0.25% Cream comes in contact with these areas accidentally, rinse with water thoroughly. Do not wash the treated areas for a minimum of 3 hours after you apply Stofine 0.25% Cream. 

Disease/Condition Glossary

Fungal infection is a skin disease in which a fungus attacks the tissue and cause infection. Fungal infections may be contagious (spread from one person to another). Ringworm is a common fungal infection of skin or scalp contagious and causes a rash resembling a worm in a ring shape. Jock itch (also known as tinea cruris) is a fungal infection of the skin that causes an itchy, red rash in warm and moist areas of the body such as the groin, buttocks, and inner thighs. Athlete’s foot (also known as tinea pedis) is a fungal infection that usually starts between the toes, especially in people who have extremely sweaty feet and wear tight-fitting shoes. It occurs most commonly in athletes. It causes itching, burning, or stinging sensation due to a scaly rash. Seborrheic dermatitis is a skin condition that causes an itchy rash with dry, flaky scales on the skin that contains oil glands such as the scalp, face, back, and upper chest.  Fungal infection in nails happens when there is an overgrowth of fungi in, under, or on the nail. Fungal infections usually occur in toenails than fingernails, likely because toes remain under shoes, in a warm, moist environment. 

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Alcohol

Safe if prescribed

No interaction found/ established. Please consult your doctor before using Stofine 0.25% Cream.

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Pregnancy

Caution

Stofine 0.25% Cream is Category C pregnancy drug and is given to a pregnant woman only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Unsafe

There is limited data on how Stofine 0.25% Cream affects breastfeeding. Please consult your doctor before starting Stofine 0.25% Cream. However, if nursing mothers apply Stofine 0.25% Cream to their breasts for treatment, it is advised to wash the affected area thoroughly before breastfeeding the baby.

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Driving

Safe if prescribed

Stofine 0.25% Cream does not influence on the ability to drive or use machines.

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Liver

Caution

If you have any concerns regarding the use of Stofine 0.25% Cream in patients with Liver problems, please consult a doctor.

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Kidney

Safe if prescribed

Stofine 0.25% Cream is safe for patients with kidney disease if prescribed by a doctor.

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Children

Safe if prescribed

Stofine 0.25% Cream is to be used on children below 12 years of age only when prescribed by the doctor.

Country of origin

India
Other Info - STO0349

Author Details

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FAQs

Stofine 0.25% Cream is used to treat fungal nail infections.
Stofine 0.25% Cream is safe to use with doctor’s advice and over a limited period (1-2 weeks). Let your doctor know if your symptoms are not relieved by then or experience any side effects.
Stofine 0.25% Cream consists of Amorolfine that should be used after consulting with doctor if a person has raised blood sugar levels (diabetes mellitus).
You are required to maintain at least a three-hour gap after application of Stofine 0.25% Cream if you are using more than one topical medicine.
No, do not stop taking Stofine 0.25% Cream on your own even if the symptoms are relieved until your course advised by the doctor is finished.
There is limited data on how Stofine 0.25% Cream affects breastfeeding. Please consult your doctor before starting Stofine 0.25% Cream. However, if nursing mothers apply Stofine 0.25% Cream to their breasts for treatment, it is advised to wash the affected area thoroughly before breastfeeding the baby.
Stofine 0.25% Cream contains 'Amorolfine' that works by stopping producing a chemical called 'ergosterol' in fungi that causes nail infection. Without ergosterol, the fungus cannot survive. As a result, infection-causing fungi die.Â
Stofine 0.25% Cream is for topical (for skin) use only. Do not put bandage or dressing on the affected area while treating with Stofine 0.25% Cream unless the doctor advised. If the medicine gets into your eyes, nose, mouth or vagina, rinse with cold water. Do not apply Stofine 0.25% Cream on open wounds, lesions and blisters.
Stofine 0.25% Cream, when used for longer periods, can cause thinning and weakening of the skin. Please stop using Stofine 0.25% Cream and immediately consult your doctor if you notice these symptoms.
Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.
You are recommended to apply makeup or sunscreen to the treated area of skin after a minimum of 20 minutes of using Stofine 0.25% Cream.
You are recommended to use Stofine 0.25% Cream for as long as your doctor has prescribed it. However, if the condition worsens or persists after 2 to 4 weeks of treatment with Stofine 0.25% Cream, please consult a doctor.
You should use Stofine 0.25% Cream as prescribed. Your doctor will recommend the dose and duration based on the type of fungal infection. It is usually applied weekly once on the affected finger or toenails. Sometimes your doctor may ask you to apply it twice a week.
No, Stofine 0.25% Cream is not a steroid. Stofine 0.25% Cream is an antifungal drug.
No, do not apply Stofine 0.25% Cream on other parts of the body like oral cavity, eyes or intravaginally. It should only be restricted to nails and skin. Follow your doctor’s instructions carefully.
Yes, Stofine 0.25% Cream may cause allergic reactions in some people. Although, it is not very common and is likely to occur in only sensitive or susceptible people. If you experience such reactions, contact your doctor immediately.
Stofine 0.25% Cream should not be used in children unless advised by a doctor.
Stofine 0.25% Cream may cause skin redness as a common side effect. However, if the condition persists or worsens, consult your doctor.
Apply Stofine 0.25% Cream as a thin layer evenly on the entire surface of the dry skin or nail. Always wash your hands after applying Stofine 0.25% Cream. Avoid contact of Stofine 0.25% Cream with ears, eyes and mucous membranes.
Stofine 0.25% Cream may cause side effects such as itching, dry skin, redness, and burning sensation of the skin. If these side effects persist or worsen, please consult your doctor.
Store Stofine 0.25% Cream at room temperature. Protect from light. Do not freeze. Keep it out of reach of children.
If you forget to use Stofine 0.25% Cream, apply it as soon as you remember. If you have concerns, discuss with your doctor.

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