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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:37 PM IST
Sameral Tablet is an amino acid used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression. This medicine helps in optimal cellular functioning, monitors and regulates important physiological functions, increases glutathione concentration and metabolism of the liver. Common side effects include nausea, diarrhoea, stomach pain, and flatulence.
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Manufacturer/Marketer

Gallberry Life Sciences Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

About Sameral Tablet

Sameral Tablet is used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression. Alcoholic liver disease occurs due to liver damage because of excessive alcohol consumption. Osteoarthritis is a condition in which the joints are affected. Depression is a mood disorder and a psychological, physiological and emotional experience that affects the way we think, the things we do and the way we act.

Sameral Tablet contains S-Adenosyl-L-Methionine, an essential amino acid required for optimal cellular functioning. Sameral Tablet is believed to monitor and regulate important physiological functions in living cells. It increases glutathione concentration and metabolism of the liver. Sameral Tablet increases chondrocyte proteoglycan synthesis, thereby helping treat osteoarthritis.

Sameral Tablet may be taken with or without food, but it is better to take it at a designated time. Sameral Tablet should be swallowed whole and not crushed or chewed. In some cases, Sameral Tablet may cause certain common side effects such as nausea, diarrhoea, stomach pain, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist. 

It is advisable to inform the doctor if you are allergic to any of the components of Sameral Tablet . Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Exercise caution when taking Sameral Tablet with any anti-Parkinsonian drugs or anti-depressants. It is not advisable to take alcohol with Sameral Tablet as there may be an interaction. Discuss your entire surgical history with your treating doctor and keep them informed of any pending surgical procedure.

Uses of Sameral Tablet

Treatment of Liver disease, osteoarthritis and depression.

Medicinal Benefits

Sameral Tablet contains S-Adenosyl-L-Methionine. Sameral Tablet helps in the synthesis of essential amino acid methionine, which is required for major body functions. It helps provide cellular energy and charge the living cells of various organs like the brain, bones and liver with stamina and fuel, thereby finding application in the treatment of depression, arthritis and liver disease. It helps in major detoxification of the liver in case of diseases caused by a retarded flow of bile such as intrahepatic cholestasis. Sameral Tablet may also find use in the treatment of fibromyalgia, chronic pain, attention deficit hyperkinetic disorder and Alzheimer’s disease. However, studies to understand the mechanism behind the same have been inconclusive.

Directions for Use

Take Sameral Tablet as directed by the physician. Swallow it whole with a glass of water. Do not crush, chew, or break it. Sameral Tablet can be taken with or without food, but it is better to take it with food.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sameral Tablet

  • Nausea

  • Diarrhoea

  • Flatulence

  • Stomach pain

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of the components of Sameral Tablet . Keep your doctor informed of your entire medical history before using Sameral Tablet . Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Exercise caution when taking Sameral Tablet with any anti-Parkinsonian drugs or anti-depressants. It is not advisable to take Sameral Tablet with alcohol as there may be an interaction. Discuss your entire surgical history with your treating doctor and keep them informed of any pending surgical procedure.

Drug Interactions

Drug-Drug Interactions: Sameral Tablet may interact with antiparkinson drug (levodopa), antidepressants (fluoxetine, paroxetine, atomoxetine, citalopram, escitalopram, sertraline), antipsychotics (olanzapine, clozapine, risperidone), painkillers (tramadol, methadone, meperidine) and anti-migraine triptans (sumatriptan, zolmitriptan).

Drug-Food Interactions: No interactions were found.

Drug-Disease Interactions: Sameral Tablet should be used with caution in patients with a known hypersensitivity disorder, mental health disorder, bipolar disorder and Parkinson’s disease. 

Drug-Drug Interactions Checker List

  • LEVODOPA
  • FLUOXETINE
  • PAROXETINE
  • RISPERIDONE
  • OLANZAPINE
  • CITALOPRAM
  • ESCITALOPRAM
  • MEPERIDINE
  • TRAMADOL
  • METHADONE
  • SUMATRIPTAN
  • ZOLMITRIPTAN
  • SERTRALINE

Habit Forming

No

Diet & Lifestyle Advise

  • Load up on lean meats, fatty fish, green leafy vegetables, fruits and nuts to enhance anti-oxidation and optimal functioning of the body.

  • Drink a lot of water and keep yourself hydrated.
  • Maintain a healthy weight by exercising for at least 30 minutes daily. 
  • Stop smoking as this can have a negative effect on the absorption of Sameral Tablet and worsen the disease conditions.

Special Advise

Inform the doctor in case of any pending surgery or surgical procedure before taking Sameral Tablet . 

Disease/Condition Glossary

Liver disease: Liver disease is a condition in which the liver does not function properly. Symptoms include severe skin itching, nausea, loss of appetite, jaundice, dark urine or stools etc. 

Osteoarthritis: Osteoarthritis is the most common type of arthritis. It occurs due to the breakdown of cartilage that cushions and protects the bones. The disease progresses gradually and tends to worsen if not treated. Symptoms include joint pain in the hips, lower back, knees and hands.

Depression: Depression is a psychological, physiological and emotional experience that affects the way we think, the things we do and the way we act. Losing interest in activities you once enjoyed, loss of appetite, feelings of guilt, low mood, low self-esteem and low energy levels are some symptoms of depression.

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Alcohol

Caution

It is not known whether it is safe to consume alcohol with Sameral Tablet . Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Sameral Tablet should be used with caution in pregnant women. Please consult a doctor if you are pregnant.

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Breast Feeding

Caution

Sameral Tablet should be used with caution in nursing mothers. Please consult a doctor.

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Driving

Caution

Sameral Tablet may rarely cause drowsiness and dizziness. Exercise caution while driving in case of these side effects.

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Liver

Consult your doctor

Sameral Tablet is possibly safe on the liver. Please consult your doctor in case of any concerns.

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Kidney

Consult your doctor

Sameral Tablet is possibly safe on the kidney. Please consult your doctor in case of any concerns.

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Children

Caution

It is not established if Sameral Tablet is safe to use in children. Please consult the treating doctor in case of any concerns.

Country of origin

India

Manufacturer/Marketer address

301/302, 3rd Floor, Saket Callipolis Sarjapur Main Road, Doddakannelli Bangalore, Karnataka 560035, India
Other Info - SAM0115

Author Details

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FAQs

Sameral Tablet is used in the treatment of mild to moderate alcoholic liver disease, osteoarthritis, and depression.
Please see an orthopaedic doctor if you have had a fracture. Sameral Tablet is used in the case of arthritis and has limited use in the treatment of fractures as a fracture is more of surgical concern.
Yes, Sameral Tablet finds a lot of benefit in treating depression. However, if you are on any anti-depressants, keep your doctor informed to avoid any interactions.
In case you miss a dose of Sameral Tablet , take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule.
Sameral Tablet is probably safe on the kidney; however, in case of CKD, it is best to consult your treating doctor before using Sameral Tablet .
Sameral Tablet works by the synthesis of methionine, which is an essential amino acid required for cellular energy.
Sameral Tablet may cause side effects such as nausea, diarrhoea, stomach pain, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.
Sameral Tablet should not be used by people who are allergic to any of its components. It is also not recommended for people with bipolar disorder, HIV, pregnant and nursing women.
Sameral Tablet contains S-Adenosylmethionine, a naturally occurring compound found in almost every tissue and fluid in the body. It is made in the body from methionine, an amino acid found in foods.
It is unknown if Sameral Tablet is safe to use for the long term. Take Sameral Tablet for the duration suggested by the doctor.

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