Nexret-TC Gel belongs to the class of dermatological preparations called 'antiacne' used to treat acne (pimples). Acne is a common skin condition and occurs when hair follicles are blocked with dead skin cells and oil. The acne-causing bacteria feeds on sebum (natural oil produced by skin) causing redness and swelling.

Nexret-TC Gel is a combination of two medicines, namely: Tretinoin (vitamin A) and Clindamycin (antibiotic). Tretinoin is a form of vitamin A that reduces oil production in the skin, replenishes the skin, and helps keep your pores open. Clindamycin belongs to the class of antibiotics that inhibits the production of essential proteins that are necessary for bacteria to grow, multiply, and increase in numbers. Altogether it stops or slows down the growth of bacteria and prevents the growth of acne.

Take Nexret-TC Gel as prescribed by your doctor. You are advised to take Nexret-TC Gel as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience application site reactions (burning, irritation, itching, and redness), dermatitis, skin peeling, and dryness. Most of these side effects of Nexret-TC Gel do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to Nexret-TC Gel or any other medicines, please tell your doctor. If you have a chronic inflammatory bowel disease (e.g. Crohn’s disease or ulcerative colitis). If you are suffering from other acute inflammatory conditions of the skin (e.g. folliculitis), especially around the mouth (perioral dermatitis). If you have a history of colitis with past antibiotic use, which is characterized by prolonged or significant diarrhoea or abdominal cramps. Do not apply Nexret-TC Gel to cuts, open wounds, broken, sunburnt, or sensitive skin areas. Avoid sun exposure while using Nexret-TC Gel as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you have intestine problems or eczema, please inform your doctor before taking Nexret-TC Gel. If you are pregnant or breastfeeding, please inform your doctor before taking Nexret-TC Gel.

Nexret-TC Gel is a combination of two medicines, namely Tretinoin (vitamin A) and Clindamycin (antibiotic), primarily used to treat acne (pimples). Tretinoin is a form of vitamin A that reduces oil production in the skin, replenishes the skin, and helps keep your pores open. Clindamycin belongs to the class of antibiotics that inhibits the production of essential proteins that are necessary for bacteria to grow, multiply, and increase in numbers. Altogether it stops or slows down the growth of bacteria and prevents the growth of acne.

• Application site reactions (burning, irritation, itching and redness)
• Dermatitis
• Skin peeling
• Dryness

If you are known to be allergic to Nexret-TC Gel or any other medicines, please tell your doctor. If you have a chronic inflammatory bowel disease (e.g. Crohn’s disease or ulcerative colitis). If you are suffering from other acute inflammatory conditions of the skin (e.g. folliculitis), especially around the mouth (perioral dermatitis). Avoid sun exposure while using Nexret-TC Gel as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you have a history of colitis (chronic digestive disease) with past antibiotic use which is characterized by prolonged or significant diarrhoea or abdominal cramps. Do not apply Nexret-TC Gel to cuts, open wounds, broken, sunburnt, or sensitive skin areas. Avoid sun exposure while using Nexret-TC Gel as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you have intestine problems or eczema, please inform your doctor before taking Nexret-TC Gel. If you are pregnant or breastfeeding, please inform your doctor before taking Nexret-TC Gel.

Drug-Drug Interactions: Nexret-TC Gel may interact with antibiotics (erythromycin, metronidazole), blood thinner (warfarin), keratolytic agents (benzoyl peroxide, salicylic acid), and skeletal muscle relaxants (atracurium, cisatracurium).

Drug-Food Interactions: If you are taking grapefruit juice or alcohol, please inform your doctor before taking Nexret-TC Gel.

Drug-Disease Interactions: If you have intestine problems or eczema, please inform your doctor before taking Nexret-TC Gel.

• ERYTHROMYCIN
• METRONIDAZOLE
• WARFARIN
• SALICYCLIC ACID
• BENZOYL PEROXIDE
• ATRACURIUM
• CISATRACURIUM

• Avoid sun exposure while using Nexret-TC Gel as it may make the skin more sensitive to sunlight and cause sunburn. Try to wear protective clothing and use a sunscreen while going out to protect your skin from sunburn.
• Regular exercise can improve your mood and self-esteem though it doesn’t clear acne. Take a shower immediately after finishing exercise as sweat may irritate acne.
• Do regular hair wash regularly and avoid hair falling across the face.
• Remove the make-up completely before going to bed.
• Avoid using products that may cause skin irritation such as harsh soaps, skin cleansers, shampoos, hair removers or waxes, hair colouring or permanent chemicals, detergents, and rough fabrics.

• You are advised to apply any other lotions, creams, or ointments including cosmetics and moisturizers after 30 minutes of applying Nexret-TC Gel as using both simultaneously may reduce the effectiveness of Nexret-TC Gel.
• Avoid contact of Nexret-TC Gel with nose, mouth, eyes, or ears. In case Nexret-TC Gel comes in contact with these areas accidentally, rinse with water.
• Do not squeeze, pop, or pick spots as it may worsen them and cause permanent scarring.

Acne (pimple): It is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads, and blackheads. Acne affects people of all ages but is most common among teenagers. Acne symptoms include pus-filled pimples, uninflamed (not swollen) blackheads, red, large, and tender bumps. The treatment for acne includes certain creams, cleansers, and antibiotics.