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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 30, 2024 | 5:56 AM IST

Neftriol Capsule is used to treat low blood calcium levels. It contains Calcitriol, which raises Vitamin D levels and thereby increases calcium levels in the blood. In some cases, this medicine may cause side effects such as stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Manufacturer/Marketer

Nephurocare Pharma Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

About Neftriol Capsule

Neftriol Capsule belongs to a group of medicines called 'vitamin D metabolites' primarily used to treat low blood calcium levels. Neftriol Capsule effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). Neftriol Capsule can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Neftriol Capsule is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.

Neftriol Capsule contains Calcitriol (Vitamin D3); it is used to prevent or treat a calcium deficiency. It is an essential nutrient to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 and treats calcium deficiency with hypoparathyroidism (the parathyroid gland's decreased activity) and metabolic bone diseases in people with chronic kidney failure. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine.

Take Neftriol Capsule as prescribed by your doctor. Depending on your medical condition, you are advised to take Neftriol Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Neftriol Capsule can cause side effects like constipation, stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache. Most of these side effects of Neftriol Capsule do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Neftriol Capsule or its inactive components, please inform your doctor. Pregnant or breastfeeding women should consult their doctor before taking Neftriol Capsule . Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Neftriol Capsule may pass into the breast milk. Hence, breastfeeding mothers need to seek medical advice before starting Neftriol Capsule . Do not take Neftriol Capsule if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Inform your doctor if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance.

Uses of Neftriol Capsule

Neftriol Capsule is used to treat Osteoporosis (weak and brittle bones), Osteomalacia/rickets (weak bones), Hypoparathyroidism (low levels of parathyroid hormone), and Latent tetany (a muscle disease with low blood calcium levels).

Medicinal Benefits

Neftriol Capsule effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). Neftriol Capsule can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Neftriol Capsule is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Neftriol Capsule

  • Hypercalcaemia (high calcium levels in the blood)
  • Loss of appetite
  • Weight loss
  • Feeling sick
  • Being sick
  • Headache and feeling sluggish
  • Drowsy or weak
  • Stomach pain or discomfort
  • Urinary tract infection
  • Rash

Drug Warnings

Before taking Neftriol Capsule , inform your doctor if you are undergoing hemodialysis due to kidney problems and have a stent in the heart. Neftriol Capsule may alter calcium levels, so it is recommended to monitor calcium levels in the blood and urine regularly. Inform your doctor immediately if you notice fever, increased thirst and urination, dehydration, bedwetting, constipation, and stomach pain, as they may sign very high calcium levels in your blood. Pregnant or breastfeeding women should consult their doctor before taking Neftriol Capsule . Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Neftriol Capsule may pass into the breast milk. Hence, breastfeeding mothers need to seek medical advice before starting Neftriol Capsule . Do not take Neftriol Capsule if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).

Drug Interactions

Drug-Drug interactions: Neftriol Capsule may interact with other medicines containing vitamin D, Steroid medicines (hydrocortisone, prednisolone, dexamethasone), a medicine used to treat high levels of cholesterol in your blood (cholestyramine), medications containing magnesium, such as antacids (used to treat indigestion), medicines used to treat heart disease (digoxin or digitoxin), and diuretic medicines (bendroflumethiazide, chlortalidone, indapamide)

Drug-Food interactions: Do not take foods enriched with vitamin D and avoid a high intake of dairy products such as milk, ghee, and cheese.

Drug-Disease interactions: Neftriol Capsule is not recommended for use in patients with bleeding disorders, hypercalcemia (high levels of calcium in the blood), metastatic calcification (extra deposits of calcium in the body), kidney problems, high blood pressure, cancer, optic nerve damage, and high levels of vitamin D.

Drug-Drug Interactions Checker List

  • HYDROCORTISONE
  • PREDNISOLONE
  • CHOLESTYRAMINE
  • DIGOXIN
  • DIGITOXIN
  • BENDROFLUMETHIAZIDE
  • CHLORTALIDONE
  • INDAPAMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
  • Eat a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables daily.
  • Snack on calcium-rich nuts like Brazil nuts or almonds.
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

Special Advise

  • Neftriol Capsule is not indicated in patients with or with a history of kidney stones, as it may increase the chance of kidney stone formation. Consult your doctor for further advice.
  • Your doctor may advise regular monitoring of calcium levels.

Disease/Condition Glossary

Osteoporosis: Osteoporosis is a bone disease that weakens and brittle bones by decreasing bone density. As bones become less dense, they weaken and are more likely to break. Breaking a bone is a serious complication of osteoporosis, especially in older patients. Women are much more likely to develop osteoporosis than are men. Signs and symptoms include back pain caused by a fractured or collapsed vertebra, loss of height over time, a stooped posture, a bone that breaks much more quickly than expected.

Osteomalacia/Rickets: A bone disease caused by softening and weakening bones in children due to inadequate vitamin D. Adults can experience a similar condition known as osteomalacia. It causes bone pain, poor growth, and soft, weak bones that can lead to bone deformities.

Tetany: A disease condition due to low calcium levels (hypocalcemia) in the body causes cramps and spasms in the hands, feet, and larynx (voice box).

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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence, it is advised to limit the alcohol intake while using Neftriol Capsule .

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Pregnancy

Caution

Use higher doses of Neftriol Capsule during pregnancy than the daily dietary allowance only when the doctor advises. Calcitriol in higher doses may harm the fetus. Your doctor will weigh the potential risks and benefits before prescribing Neftriol Capsule .

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Breast Feeding

Caution

Consult your doctor before taking Neftriol Capsule if you are breastfeeding. Neftriol Capsule can pass into the breast milk. If Neftriol Capsule is used during breastfeeding, please monitor the mother and the infant's serum calcium levels.

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Driving

Safe if prescribed

Neftriol Capsule may not affect your ability to drive.

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Liver

Caution

Before taking $ name, let your doctor know if you have any history of liver disease. Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.

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Kidney

Caution

It is advised to seek a doctor's advice before starting Neftriol Capsule if you have kidney diseases like kidney stones or are undergoing dialysis. Calcitriol in Neftriol Capsule increases inorganic phosphate levels in serum; hence, caution should be taken in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).

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Children

Caution

Neftriol Capsule should be used with caution in children and only if prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

Nephurocare Pharma Pvt. Ltd. , E-609, Titanium City Center, Nr. 100Ft Road, Anand Nagar, Satellite, Ahmedabad - 380015, Gujarat, India
Other Info - NEF0047

Author Details

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FAQs

Neftriol Capsule belongs to a group of medicines called ‘vitamin D metabolites’ primarily used to treat low blood calcium levels. Neftriol Capsule effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels).
Neftriol Capsule contains calcitriol, which works by helping the body absorb more calcium from the diet. This helps to form healthy bones and reduce bone damage.
Neftriol Capsule can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Neftriol Capsule as a daily supplement if you have any kidney problems or a history of kidney stones.
Neftriol Capsule is used to increase low calcium levels in the body. Hence, it is not advised to use Neftriol Capsule during hypercalcemia since it causes an overdose of calcium, leading to kidney stones and other effects.
Do not use Neftriol Capsule if you are allergic to any of the ingredients in Neftriol Capsule . It is not recommended in hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).

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