Lignorain 2% Injection

Lignorain 2% Injection is indicated for the production of regional or local anaesthesia during surgery or medical procedures. Additionally, it is indicated in the management of ventricular arrhythmia (abnormal heartbeat) associated with acute myocardial infarction, or cardiac surgery. 

Lignorain 2% Injection contains ‘Lidocaine’ that blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses; hence providing an anaesthetic effect. Lignorain 2% Injection blocks cardiac sodium channels, thereby treating arrhythmia.

Lignorain 2% Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience certain common side-effects such as dizziness, high/low blood pressure, nausea, vomiting, and paresthesia (burning or prickling sensation). You are advised to talk to your doctor if you experience these side effects persistently.

Do not take Lignorain 2% Injection if you are allergic to any of its components. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding. Avoid driving or operating machinery as Lignorain 2% Injection may cause dizziness, drowsiness, and loss of sensation. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Lignorain 2% Injection is indicated for the production of regional or local anaesthesia in case of surgeries or medical procedures. Also, it is indicated in the management of ventricular arrhythmias (abnormal heartbeat) associated with acute myocardial infarction, or cardiac surgery. Lignorain 2% Injection blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses and hence providing an anaesthetic effect. It blocks cardiac sodium channels, thereby treating arrhythmia.

• Nausea
• Vomiting
• High/low blood pressure
• Dizziness
• Paresthesia (burning or prickling sensation)

Do not take Lignorain 2% Injection if you are allergic to any of its components. Inform your doctor if you have hypovolemia (low blood volume), blood clotting problems, bleeding problems, slow heart rate, myasthenia gravis (muscle problems), epilepsy, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Avoid driving or operating machinery as Lignorain 2% Injection may cause dizziness, drowsiness and loss of sensation. Keep your doctor informed about your health condition and medications to rule out any interactions/side effects.

Drug-Drug Interactions: Inform your doctor if you are taking other anaesthetics, antiarrhythmics, anti-viral agents, sedatives, beta-blockers (metoprolol, propranolol), calcium channel blockers (amiodarone), vasoconstrictors (epinephrine, norepinephrine), antacid (cimetidine), anti-convulsants (phenobarbital, phenytoin, carbamazepine, primidone), antibiotic (erythromycin), anti-psychotics (fluvoxamine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interaction: Inform your doctor if you have hypovolemia (low blood volume), blood clotting problems, bleeding problems, slow heart rate, myasthenia gravis (muscle problems), epilepsy, heart, kidney or liver problems.

• METOPROLOL
• PROPRANOLOL
• AMIODARONE
• EPINEPHRINE
• NOREPINEPHRINE
• CIMETIDINE
• PHENOBARBITAL
• PHENYTOIN
• CARBAMAZEPINE
• PRIMIDONE
• ERYTHROMYCIN
• FLUVOXAMINE

• Include a diet rich in whole grains, lean proteins, vegetables, and fruits.
• Avoid smoking and alcohol consumption.
• Maintain a healthy weight with a proper diet and safe exercises.
• Manage stress with meditation and yoga.

Local anaesthesia: It causes numbing/loss of sensation to a specific area of the body. It is used to treat pain, or to prevent pain during surgery or medical procedure.

Ventricular arrhythmia: Ventricular arrhythmia is a condition in which abnormal heartbeats originate in the ventricles (lower chambers of the heart). This limits/prevents the heart's ability to pump blood throughout the body. Symptoms include palpitations (a feeling as if the heart is pounding), chest pain, fainting, sweating, shortness of breath, and light-headedness.