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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Knee-Joint Tablet is used to relieve pain associated with osteoarthritis. It slows down the breakdown of cartilage, reduces inflammation and helps repair joints. In some cases, this medicine may cause side effects such as headache, tiredness, nausea, abdominal pain, and indigestion. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Indizen Pharmaceuticals

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-25

for this medicine

About Knee-Joint Tablet

Knee-Joint Tablet is used to reduce the pain of osteoarthritis (OA). Osteoarthritis is a chronic (lifelong) joint condition in which glucosamine sulfate (a chemical found in the human body, especially in joints) gets reduced. When this chemical gets reduced, the cartilage breaks down and becomes thin, which causes friction between the bones, leading to wear and tear (damage) of the joint tissues. Symptoms include pain, stiffness, inflammation of the joints, and reduced locomotion.

Knee-Joint Tablet contains Diacerein, Dimethyl sulfoxide, and Glucosamine. Diacerein slows down the breakdown of cartilage and helps to reduce pain and swelling. Dimethyl sulfoxide reduces the inflammation of the joints. Glucosamine reduces the breakdown of cartilage and helps to repair joints. Together, Knee-Joint Tablet can lower pain, swelling, and inflammation of the joints.

You should take this medicine as your doctor has instructed. The common side-effects of Knee-Joint Tablet are headache, tiredness, nausea, abdominal pain, indigestion, onion-like taste in the mouth, diarrhoea, discolouration of the urine, constipation, and wind (flatulence). These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.

It is not recommended to take Knee-Joint Tablet if you are allergic to any of its contents, shellfish, or soya. Before taking Knee-Joint Tablet , inform your doctor if you have glucose intolerance, liver or kidney disease, high cholesterol, asthma, bladder or kidney cancer, and vision problems. It is not recommended for use in children, pregnant women, and breastfeeding mothers. It should be used with caution in the elderly. Avoid alcohol consumption as it may increase the risk of side effects. Knee-Joint Tablet may decrease alertness, so do not drive or operate heavy machinery if you are not fully alert.

Uses of Knee-Joint Tablet

Treatment of Osteoarthritis

Medicinal Benefits

Knee-Joint Tablet improves joint's movement and flexibility by helping in the formation of cartilage (the soft tissue that cushions the joints) and lubricating the joints. It helps to repair joints and slow down the progression of the disease. It helps to relieve pain, swelling, and inflammation of the joints. Pain relief and improved motility can help you to perform daily activities easily.

Directions for Use

Swallow Knee-Joint Tablet as a whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Knee-Joint Tablet

  • Headache
  • Tiredness
  • Nausea
  • Abdominal pain
  • Indigestion
  • Onion-like taste in the mouth
  • Diarrhea
  • Discoloration of the urine
  • Constipation
  • Wind (flatulence)

Drug Warnings

Knee-Joint Tablet may cause high cholesterol, so it should be used with caution in patients with heart disease risk. Knee-Joint Tablet may worsen the symptoms of asthma. You may notice discoloration of urine and an onion-like taste in the mouth. However, these effects are mild and do not require medical attention. If you notice any changes in vision while using Knee-Joint Tablet , inform your doctor immediately as this medicine may increase pressure in the eye.

Drug Interactions

Drug-Drug Interactions: Knee-Joint Tablet may interact with a blood thinner (warfarin), antidiabetic medicines (metformin, glimepiride, and glibenclamide, etc.), and antibiotic (tetracycline).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Knee-Joint Tablet should be used with caution in patients with glucose intolerance, liver or kidney disease, high cholesterol, asthma, bladder or kidney cancer, and vision problems.

Drug-Drug Interactions Checker List

  • WARFARIN
  • METFORMIN
  • GLIBENCLAMIDE
  • GLIMEPIRIDE
  • TETRACYCLINE

Habit Forming

No

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.

  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.

  • In the chronic condition of arthritis or joint pain, including fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.

  • Your sitting posture is important, especially when you have pain and inflammation conditions. Try to sit little as possible, and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Special Advise

  • Your doctor may advise you to regularly monitor blood glucose levels while using Knee-Joint Tablet .  
  • Patients taking anticoagulant therapy should be carefully monitored during the treatment with Knee-Joint Tablet .

Disease/Condition Glossary

Osteoarthritis: Osteoarthritis is a chronic (lifelong) joint condition in which glucosamine sulfate (a chemical found in the human body, especially in joints) gets reduced. The body uses this fluid to produce other chemicals required to make ligaments, cartilage, tendons, and the thick fluid surrounding joints. When this chemical gets reduced, the cartilage breaks down. It becomes thin, which causes friction between the bones, leading to wear and tear (damage) of the joint tissues, leading to pain, stiffness, inflammation, and reduced locomotion.  It causes the bone to rub together, leading to pain, stiffness, and other osteoarthritis symptoms. This disease can occur in any joint, but commonly affected areas of the body are hands, fingertips, knees, hips, spine, typically at the neck or lower back. The most common symptoms of osteoarthritis include pain, tenderness (discomfort when pressing on the area with fingers), stiffness, and inflammation.

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Alcohol

Caution

Avoid consuming alcohol while taking Knee-Joint Tablet as it may increase the risk of side-effects.

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Pregnancy

Unsafe

Knee-Joint Tablet may cause harmful effects on the unborn baby, so your doctor may recommend Knee-Joint Tablet only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Knee-Joint Tablet may pass into breastmilk. Consult your doctor before taking Knee-Joint Tablet , your doctor will decide whether Knee-Joint Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Knee-Joint Tablet may decrease alertness, so do not drive or operate machinery if you are not fully alert.

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Liver

Caution

Knee-Joint Tablet should be used with caution in patients with liver diseases. The dose may have to be adjusted by the doctor as required.

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Kidney

Caution

Knee-Joint Tablet should be used with caution in patients with liver diseases. The dose may have to be adjusted by the doctor as required.

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Children

Unsafe

Knee-Joint Tablet should not be given to children and adolescents below 18 years as safety and efficacy have not been established.

Country of origin

India

Manufacturer/Marketer address

208/27, Aggarsain Chowk, Delhi Road, Jind - 126102, Haryana, India
Other Info - KNE0344

Author Details

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FAQs

Knee-Joint Tablet is used to reduce the pain of osteoarthritis (OA).
Knee-Joint Tablet contains Diacerein, Dimethyl sulfoxide, and Glucosamine. Diacerein is a slows down the breakdown of cartilage and helps to reduce pain and swelling. Dimethyl sulfoxide reduces the inflammation of the joints. Glucosamine reduces the breakdown of cartilage and helps to repair joints. Together, Knee-Joint Tablet can lower pain, swelling, and inflammation of the joints.
No, Knee-Joint Tablet contains glucosamine made from shellfish, so it is not recommended to use Knee-Joint Tablet in patients who are allergic to shellfish.
The common side-effects of Knee-Joint Tablet are headache, tiredness, nausea, abdominal pain, indigestion, onion-like taste in the mouth, diarrhea, discoloration of the urine, constipation, and wind (flatulence). These side-effects are usually mild and temporary. However, if any of these side-effects persist or get worse, inform your doctor immediately.
Knee-Joint Tablet may increase pressure inside the eye and worsen glaucoma. So, please consult your doctor to know the potential risks associated with this medicine if you have glaucoma.
Knee-Joint Tablet may affect eyes by increasing the pressure inside the eye. So, it is essential to undergo eye examinations regularly while using this medicine.

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