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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 30, 2024 | 5:52 AM IST

Gionerv PG-50 Capsule 10's is used to treat neuropathic pain. It helps rejuvenate and protect damaged nerve cells. Also, it helps in providing a protective effect on the nerve tissues and brain. Therefore, it helps provide relief from neuropathic pain. In some cases, you may experience certain common side effects such as dizziness, sleepiness, tiredness, nausea and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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About Gionerv PG-50 Capsule 10's

Gionerv PG-50 Capsule 10's is a combination medicine used to treat neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to nerve damage or malfunctioning of the nervous system. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events that are usually not painful).

Gionerv PG-50 Capsule 10's is a combination of three drugs: Pregabalin, methylcobalamin and alpha-lipoic acid. Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain. Together, Gionerv PG-50 Capsule 10's helps in providing relief from neuropathic pain.

You are advised to take Gionerv PG-50 Capsule 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as dizziness, sleepiness, tiredness, nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Gionerv PG-50 Capsule 10's causes drowsiness and dizziness, so drive only if you are alert. Gionerv PG-50 Capsule 10's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Gionerv PG-50 Capsule 10's as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Gionerv PG-50 Capsule 10's

Treatment of Neuropathic pain.

Medicinal Benefits

Gionerv PG-50 Capsule 10's is used to treat neuropathic pain. Gionerv PG-50 Capsule 10's is a combination of three drugs: Pregabalin, methylcobalamin and alpha-lipoic acid. Pregabalin is an anticonvulsant which affects the chemicals in the brain that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain and lowers the risk of seizures. Methylcobalamin is a form of vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid is an antioxidant that helps protect nerve tissues and the brain. Together, Gionerv PG-50 Capsule 10's helps in providing relief from neuropathic pain.

Directions for Use

Take Gionerv PG-50 Capsule 10's with or without food. Swallow Gionerv PG-50 Capsule 10's as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Gionerv PG-50 Capsule 10's

  • Dizziness
  • Tiredness
  • Nausea
  • Dry mouth
  • Constipation
  • Vomiting

Drug Warnings

Do not take Gionerv PG-50 Capsule 10's if you are allergic to any of its contents. Inform your doctor before taking Gionerv PG-50 Capsule 10's if you have/had heart problems or bipolar syndrome. Consult your doctor if you are pregnant or breastfeeding. Gionerv PG-50 Capsule 10's may cause drowsiness and dizziness, so drive only if you are alert. Gionerv PG-50 Capsule 10's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Gionerv PG-50 Capsule 10's as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug Interactions

Drug-Drug Interactions: Gionerv PG-50 Capsule 10's may interact with antidepressant medications (amitriptyline, duloxetine, mirtazapine, fluoxetine, sertraline), anticonvulsants (gabapentin), anti-anxiety medications (diazepam, alprazolam), anti-diabetic medications (metformin), antibiotic medications (chloramphenicol), and pain killers (codeine, fentanyl, hydrocodone, morphine, oxycodone, tramadol).

Drug-Food Interactions: Avoid consumption of alcohol while taking Gionerv PG-50 Capsule 10's as it might cause increased dizziness and sleepiness.

Drug-Disease Interactions: Inform your doctor if you have suicidal tendencies, angioedema, creatine kinase elevations, peripheral oedema, malabsorption or anaemia.

Drug-Drug Interactions Checker List

  • AMITRIPTYLINE
  • DULOXETINE
  • MIRTAZAPINE
  • FLUOXETINE
  • SERTRALINE
  • CODEINE
  • FENTANYL
  • HYDROCODONE
  • MORPHINE
  • OXYCODONE
  • TRAMADOL
  • GABAPENTIN
  • DIAZEPAM
  • ALPRAZOLAM
  • METFORMIN
  • CHLORAMPHENICOL

Habit Forming

No

Diet & Lifestyle Advise

  • Include food rich in vitamins B and D in your diet.
  • Include cayenne pepper in your diet, as it can help in lowering neuropathic pain.
  • Exercising regularly helps improve overall health and combat pain. 
  • Rest well, and get plenty of sleep.
  • Try taking a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, and it is felt as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events that are usually not painful).

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Gionerv PG-50 Capsule 10's as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns about this. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Gionerv PG-50 Capsule 10's; your doctor will decide whether breastfeeding mothers can take Gionerv PG-50 Capsule 10's or not.

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Driving

Caution

Gionerv PG-50 Capsule 10's may cause drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Gionerv PG-50 Capsule 10's should not be given to children as the safety and efficacy have not been established.

Country of origin

India

Manufacturer/Marketer address

Sanbrio Healthcare
Other Info - GIO0025

Author Details

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FAQs

Gionerv PG-50 Capsule 10's is used to treat neuropathic pain, a chronic progressive nerve disease which causes nerve pain due to nerve damage.
Gionerv PG-50 Capsule 10's contains Pregabalin, methylcobalamin and alpha-lipoic acid. Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. It works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Alpha-lipoic acid helps in providing a protective effect on the nerve tissues and brain.
To treat your condition effectually, continue taking Gionerv PG-50 Capsule 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Gionerv PG-50 Capsule 10's, your doctor will reduce the dose gradually.
Gionerv PG-50 Capsule 10's is a combination of Alpha lipoic acid, Methylcobalamin and Pregabalin as its active substances.
Yes, Gionerv PG-50 Capsule 10's may cause weight gain. If you have diabetes and gain weight while taking Gionerv PG-50 Capsule 10's, consult your doctor as you may need an alteration in your diabetic medicines.

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