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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Durolane 60 mg Injection is used in the treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to non-pharmacologic therapy, nonsteroidal anti-inflammatory drugs (NSAIDs), or simple analgesics (pain killers). It contains Hyaluronic acid, which works by reducing friction between the joints. Thereby providing relief from pain. In some cases, it may cause common side effects such as diarrhoea, headache, loss of appetite, nausea, vomiting, and stomach pain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer

Dr Reddy's Laboratories Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Durolane 60 mg Injection

Durolane 60 mg Injection is indicated in the treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to non-pharmacologic therapy, nonsteroidal anti-inflammatory drugs (NSAIDs), or simple analgesics (pain killers).

Durolane 60 mg Injection contains 'Hyaluronic acid' that works by reducing friction between the joints. Thereby providing relief from pain.

In some cases, Durolane 60 mg Injection may cause common side effects such as diarrhoea, headache, loss of appetite, nausea, vomiting, and stomach pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Durolane 60 mg Injection is not recommended for people below 21 years. Consult your doctor if you are pregnant or breastfeeding. The safety and efficacy of Durolane 60 mg Injection have not been established for use in joints other than the knee. Inform your doctor if you have a joint infection or skin disease in the affected area.

Uses of Durolane 60 mg Injection

Treatment of Osteoarthritis

Medicinal Benefits

Durolane 60 mg Injection is indicated in the treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to non-pharmacologic therapy, nonsteroidal anti-inflammatory drugs (NSAIDs), or analgesics (pain killers). Durolane 60 mg Injection works by reducing friction between the joints. Thereby providing relief from pain.

Directions for Use

Durolane 60 mg Injection will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Durolane 60 mg Injection

  • Diarrhoea
  • Headache
  • Loss of appetite
  • Nausea
  • Vomiting
  • Stomach pain

Drug Warnings

Do not take Durolane 60 mg Injection if you are allergic to any of its contents, if you have knee joint infections or skin disease in the area of the injection site. Inform your doctor if you have chondrocalcinosis (accumulation of calcium pyrophosphate dihydrate crystals in and around the joints), blood clots, bleeding problems, blood circulation problems, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Durolane 60 mg Injection is not recommended for people below 21 years.

Drug Interactions

Drug-Drug Interaction: Durolane 60 mg Injection may interact with disinfectants (cetylpyridinium, benzalkonium chloride).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: Inform your doctor if you have skin infections, joint infections, bleeding problems, or blood clot problems.

Drug-Drug Interactions Checker List

  • BENZALKONIUM CHLORIDE
  • CETYLPYRIDINIUM

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.

Disease/Condition Glossary

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation and tenderness. The main reason for osteoarthritis is age, the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include a past injury such as torn cartilage, dislocated joints and ligament injuries. 

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Alcohol

Caution

You are recommended not to consume alcohol along with Durolane 60 mg Injection to avoid unpleasant side-effects.

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Pregnancy

Caution

The safety and effectiveness of Durolane 60 mg Injection in pregnant women have not been established. Please consult your doctor.

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Breast Feeding

Caution

The safety and effectiveness of Durolane 60 mg Injection in breastfeeding women have not been established. Please consult your doctor.

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Driving

Caution

In some cases, Durolane 60 mg Injection may cause dizziness and drowsiness. So, drive or operate machinery only if you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Durolane 60 mg Injection is not recommended for people below 21 years of age as the safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy'S Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, India
Other Info - DUR0252

FAQs

Durolane 60 mg Injection is indicated in the treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to non-pharmacologic therapy, nonsteroidal anti-inflammatory drugs (NSAIDs), or simple analgesics (pain killers).
Durolane 60 mg Injection works by reducing friction between the joints. Thereby providing relief from pain.
The safety and effectiveness of Durolane 60 mg Injection in joints other than the knee have not been established. So its use in other joints than the knee should be avoided.
Hyaluronic acid is a natural viscous gel fluid found in the joints of the body. This fluid works as a lubricant and shock absorber for smooth movement. It reduces friction and provides lubrication. When Hyaluronic acid gets reduced, it causes the bone to rub together leading to pain, stiffness, and other symptoms associated with osteoarthritis.
Avoid jogging or high-impact sports such as soccer or tennis. Also, avoid weight-bearing activity or standing for longer than 1 hour at a time. Consult your doctor if you have any concerns.

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