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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 10, 2024 | 7:17 PM IST
Debrifine Ointment is used to remove dead skin and promote wound healing. It contains Papain and Urea which increase moisture, soften the skin, and accelerate healing. In some cases, it may cause side effects like burning sensation, itching, and irritation in the application area. It is for external use only.
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Manufacturer/Marketer

Best Biotech

Consume Type

TOPICAL

Return Policy

Not Returnable

for this medicine

About Debrifine Ointment

Debrifine Ointment belongs to the class of medications called 'Debridement agents' used to remove dead skin, thereby improving healing. It also helps thin the pus in lesions (ulcers, cysts, bedsores, surgical wounds).

Debrifine Ointment contains Papain and Urea. These two medicines are keratolytic agents, increase moisture in the skin, and dissolve the keratin (protein present on the skin's outer layer). This effect makes dead skin cells fall off and accelerate healing. It also has an emollient effect and helps to soften the skin.

You should use this medicine exactly as prescribed by the doctor. The common side effects of Debrifine Ointment are a burning sensation, itching, and irritation in the treated area. These side effects are usually mild and temporary. However, if these side effects persist or worsen, inform your doctor immediately.

It is not recommended to take Debrifine Ointment if you are allergic to any contents of it. Before taking Debrifine Ointment, inform your doctor if you have liver or kidney disease and poor blood circulation. Do not use this medication on skin cuts, infections, or sores. Debrifine Ointment should be used with caution in pregnant women, breastfeeding mothers, and older people. It is not recommended for use in children less than two years. Debrifine Ointment may not interact with alcohol and may not affect your driving ability.

Uses of Debrifine Ointment

Treatment of Dead skin removal, Wound healing.

Medicinal Benefits

Debrifine Ointment belongs to the class of medications called 'Debridement agents' used to remove dead skin and promote wound healing. Debrifine Ointment contains Papain and Urea, which help remove dead skin from wounds and speed up recovery. It also helps thin the pus in lesions (ulcers, cysts, bedsores, surgical wounds). These two medicines increase moisture in the skin and dissolve keratin (a protein on the skin's outer layer). This effect makes dead skin cells fall off and accelerate healing. It also has an emollient effect and helps to soften the skin.

Directions for Use

Gently rinse the affected area with saline or water before applying Debrifine Ointment. Pat the skin and dry it with a clean cotton towel. Apply a generous amount of Debrifine Ointment and spread it evenly on the affected areas of the skin to form a 1/8-inch thick layer with clean and dry hands. You can also apply Debrifine Ointment with a piece of clean cotton wool or gauze swab. Wash your hands before and after using Debrifine Ointment on the affected areas unless the treatment is for hands.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Debrifine Ointment

  • Burning sensation
  • Itching of treated skin
  • Skin irritation

Drug Warnings

Debrifine Ointment is for topical (skin) use only. Do not use the medicine in and around your eyes. If the medicine accidentally gets into your eyes, nose, mouth, or genitals, rinse it with water thoroughly. It should not be given to children with a fever, especially if they have flu symptoms or chickenpox. Debrifine Ointment may increase skin sensitivity to the sun, so take necessary precautions while going outside and avoid tanning beds or sunlamps. If you notice any persistent skin irritation or worsening of the skin disease, stop using Debrifine Ointment and immediately inform your doctor.

Drug Interactions

Drug-Drug Interactions: Debrifine Ointment is known to interact with other topical medicines containing hydrogen peroxide, silver nitrate, silver sulfadiazine, silver, mercury, lead, and thimerosal.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Debrifine Ointment should be used with caution in patients with liver or kidney diseases and poor blood circulation.

 

Drug-Drug Interactions Checker List

  • HYDROGEN PEROXIDE
  • SILVER NITRATE
  • SILVER
  • SILVER SULFADIAZINE
  • THIMEROSAL

Habit Forming

No

Diet & Lifestyle Advise

  • Use mild soap while taking baths and prefer warm baths.
  • Avoid harsh products on your skin.
  • Do not scratch or pick your skin to avoid infecting the affected area.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Limit food intake that might trigger allergies, such as dairy products, soy, eggs, and nuts.
  • Avoid consuming foods with excess sugar, as it may flare up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats, and fish.
  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.
  • Wear clothes with long sleeves, a hat, and sunscreen with high SPF while outdoors.
  • Avoid tanning booths and sunlamps.

Special Advise

  • Before applying Debrifine Ointment, avoid using hydrogen peroxide to clean your wound, as it might affect the effectiveness of Debrifine Ointment.
  • If there is no improvement in your condition after 4-6 weeks of treatment with Debrifine Ointment, consult your dermatologist.

Disease/Condition Glossary

Debridement: It is a procedure for treating wounded skin. These agents help to remove dead skin and tissues from wounds, including ulcers, cysts, bedsores, and surgical wounds. Sometimes, it is also used to remove foreign material from tissues. It also helps to speed up the healing process of wounds.

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Alcohol

Safe if prescribed

Debrifine Ointment may not interact with alcohol.

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Pregnancy

Caution

Debrifine Ointment contains urea, a Category C pregnancy drug that may cause harmful effects on the unborn baby. So, it is given to a pregnant woman only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known whether Debrifine Ointment can pass into breast milk. So, it is given to a breastfeeding mother only if the doctor thinks the benefits outweigh the risks.

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Driving

Safe if prescribed

Debrifine Ointment may not affect your ability to drive.

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Liver

Caution

Debrifine Ointment should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Debrifine Ointment should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

Debrifine Ointment is not recommended for children below two years. In children above two years, it is given only if the doctor thinks the benefits outweigh the risks.

Manufacturer/Marketer address

817, DEVPATH B / h Lal Bungalow , Off C. G. Road, Navrangpura, Ahmedabad - 380006.
Other Info - DE48752

Author Details

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FAQs

Debrifine Ointment is used to remove dead skin, thereby improving healing.
Debrifine Ointment contains Papain and Urea. These two medicines are keratolytic agents (soften, separate, and peel off the horny layer of skin). They dissolve the keratin (protein present on the outer layer of skin), remove dead skin cells, and soften the skin.
The common side effects of Debrifine Ointment are a burning sensation, itching, and irritation in the treated area. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, inform your doctor immediately.
It is advised to avoid using other topical medicines on the affected area while using Debrifine Ointment. So, inform your doctor before using any medications while using the Debrifine Ointment. If the doctor prescribes other skin creams or ointments along with Debrifine Ointment, you should maintain an interval of at least 30 min between the two medications.
Debrifine Ointment should not be used to treat diaper rash or redness. It is not recommended for use in children below 2 years of age.
Debrifine Ointment is for topical use (for skin) only. Do not use the Debrifine Ointment on the skin that is red, swollen, oozing, and infected, and avoid contact with eyes, nose, mouth, and genitals. It can make your skin more sensitive to the harmful effects of sunlight. So, using sunscreen and wearing protective clothing while using Debrifine Ointment is advised. It is recommended to avoid tanning booths and sunlamps. Please do not use it on larger areas and for prolonged periods unless prescribed by the doctor.
Yes, Debrifine Ointment can be used for diabetic foot ulcers if advised by your doctor. It works by removing dead tissue and promotes healing.
Yes, Debrifine Ointment can be used for post-surgical wound care, if advised by your doctor. It helps in removing dead tissue and promoting the growth of healthy skin. Thus, helps in the healing process of surgical wounds.
The healing time for wounds using Debrifine Ointment can vary depending on the size and type of wound, as well as the health of the patient. Usually, you may see improvement within 2 to 4 weeks. However, it may take longer for full healing. Continue using the Debrifine Ointment as prescribed and consult your doctor if you notice any signs of infection or if the wound isn't healing.
Yes, you can use this Debrifine Ointment along with oral antibiotics if prescribed by your doctor. Debrifine Ointment helps to remove dead tissue and thin pus in lesions, while oral antibiotics can help fight any underlying infection. However, it is important to consult your doctor before taking Debrifine Ointment with other medicines to ensure it is appropriate for your specific condition and to avoid any potential interactions.
If you experience severe skin reactions such as burning, irritation, or swelling, stop using the Debrifine Ointment and consult your doctor immediately.
Yes, Debrifine Ointment can be applied to burns if advised by your doctor. As it helps remove dead tissue and thin pus in lesions, which is useful in the healing process.
Debrifine Ointment should only be used in pregnancy or breastfeeding if it is prescribed your doctor. As Debrifine Ointment contains urea, a category C pregnancy drug that may cause harmful effects on the unborn baby.

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