Apiup Syrup is used to stimulate the appetite and treat alimentary tract and metabolism problems. Apiup Syrup helps in the treatment of lack of appetite, weight loss and anorexia nervosa (an eating disorder with low body weight). Besides this, it is also prescribed for underweight children who have an inadequate dietary intake, loss of appetite, anaemia, liver/digestive disorder and as an adjunct to anti-tubercular (anti-TB drugs) and antiretroviral (anti-HIV drugs) treatment for weight gain.

Apiup Syrup is a combination of two drugs, namely: Cyproheptadine (antihistamine/antiallergic) and Tricholine (bile acid binder). Cyproheptadine works by reducing the effect of a chemical messenger in the hypothalamus called serotonin, thereby helps to stimulate the appetite. On the other hand, Tricholine is a bile acid-binding agent that works by removing excess bile acid by producing more bile acid utilizing more cholesterol in this process which in turn lowers the fat content in our body.

You are advised to take Apiup Syrup for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dry mouth, drowsiness, confusion, and ataxia (impaired balance or coordination). Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Inform your doctor before taking Apiup Syrup if you have asthma, hyperthyroidism, high blood pressure, intraocular (eye) pressure or heart problems. Consult your doctor before taking Apiup Syrup if you are pregnant. It is not recommended to take Apiup Syrup if you are breastfeeding. Apiup Syrup may cause drowsiness, so drive with caution. Avoid consumption of alcohol while taking Apiup Syrup as it may cause increased drowsiness. Keep your doctor informed about all the medicines and your health condition to rule out any side-effects.

Apiup Syrup belongs to a group of medicines called Appetite enhancers used to stimulate the appetite and increase body metabolism. Apiup Syrup is indicated for loss of appetite, weight loss and anorexia nervosa (an eating disorder with low body weight). Apiup Syrup is also prescribed for underweight children who have an inadequate dietary intake, loss of appetite, anaemia, liver or digestive disorder. Additionally, Apiup Syrup is also used as an adjunct to anti-tubercular (anti TB) and antiretroviral treatment (anti-HIV) for weight gain. Apiup Syrup helps in stimulation of appetite, ensures weight gain, provides effective hepatoprotective action and enhances protein synthesis. It is also indicated in hepatobiliary disorder (liver disease) associated with anorexia (lack/loss of appetite). 

• Nausea
• Vomiting
• Urine retention
• Dry mouth
• Drowsiness
• Confusion
• Restlessness

Do not take Apiup Syrup if you are allergic to any of its contents, if you have glaucoma, peptic ulcers, prostatic hypertrophy, bladder neck obstruction or pyloroduodenal obstruction. Inform your doctor before taking Apiup Syrup if you have asthma, hyperthyroidism, high blood pressure, intraocular (eye) pressure or heart problems. Apiup Syrup may show additive effects if taken along with alcohol, CNS depressants and anti-anxiety drugs. Consult your doctor before taking Apiup Syrup if you are pregnant. It is not recommended to take Apiup Syrup if you are breastfeeding. Apiup Syrup may cause drowsiness, so drive with caution. Avoid consumption of alcohol while taking Apiup Syrup as it may cause increased drowsiness. 

Drug-Drug Interactions: Apiup Syrup may interact with an antihistamine (diphenhydramine, cetirizine), antidepressants (duloxetine, fluoxetine, sertraline), anti-convulsant (pregabalin, topiramate), narcotic analgesics (morphine, methadone, oxycodone) and anti-psychotic (quetiapine).

Drug-Food Interactions:  No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have asthma, heart, kidney or liver problems.

• DIPHENHYDRAMINE
• CETIRIZINE
• DULOXETINE
• FLUOXETINE
• SERTRALINE
• PREGABALIN
• TOPIRAMATE
• QUETIAPINE
• MORPHINE
• METHADONE
• OXYCODONE

• Exercise regularly as it helps in increasing your energy expenditure, thereby helps in increasing hunger.
• You may eat more if you are having a good time during your meal. So, try to make mealtimes enjoyable by eating with friends, family or watching a favourite show.
• Change your menu and eat food that you enjoy.
• Try not to skip meals. Make time for eating. 
• If you feel eating three times as overwhelming, eat six smaller meals.
• Include calorie-containing beverages in your diet, such as protein shakes, fruit juices, milk, etc.
• Proper management of basic hygiene and bowel regularity can positively affect appetite in adults.
• Setting the alarm for mealtime or posting a meal schedule on the wall could be helpful for adults to remind them to eat.
• Limit excessive snacking in between meal times.
• If you have trouble obtaining, or preparing food or if you have difficulty with limited food choices, try delivery services which deliver fully prepared healthy meals.

• Tell your doctor if you have been taking or have taken anti-depressants (monoamine-oxidase inhibitors) in last 14 days.
• Your doctor may recommend regular eye checkup, as Apiup Syrup may rarely worsen the symptoms in people with glaucoma.

Anorexia (loss of appetite): It is a condition in which an individual has no desire to eat food. Lack of appetite causes missing meals or less urge of hungriness which results in a deficiency of essential and non-essential nutrients required for the proper metabolism and growth of our body. The most common reasons for the decrease in appetite include psychological conditions like stress, anxiety, depression, gastrointestinal conditions (such as acidity, peptic ulcers, and ulcerative colitis), slow metabolism, age, lowered activity levels, other disease conditions (like AIDS, HIV, cancer) and some medication side effects.