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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:28 PM IST

Actirfic 1500Mcg/2Ml Injection belongs to the class of vitamins used in the treatment of peripheral neuropathies and megaloblastic anaemia. This medicine contains methylcobalamin which helps protect the nerves from damage and promotes blood cell production. Some of the common side effects include nausea, vomiting, diarrhoea, loss of appetite, and headache.

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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Gagnant Healthcare Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Actirfic 1500Mcg/2Ml Injection

Actirfic 1500Mcg/2Ml Injection is used to treat peripheral neuropathies and megaloblastic anaemia caused by vitamin B12 deficiency. Vitamin B12 is a vital dietary nutrient, and deficiency of vitamin B12 can lead to peripheral neuropathy, megaloblastic anaemia, and many other serious conditions.

Actirfic 1500Mcg/2Ml Injection contains Mecobalamin, a form of vitamin B12 that helps protect the nerves from damage and also helps to promote blood cell production. It regulates body functions, such as cell multiplication, blood formation, and protein synthesis.

Actirfic 1500Mcg/2Ml Injection is a prescription-only medication. It will be administered by a healthcare professional; do not self-administer. You may experience pain, itching, swelling or redness around the injection site, nausea, vomiting, diarrhoea, and headache. Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you have signs of an allergic reaction, such as swelling of the face, lips, or tongue or breathing problems.

To treat your condition effectually, continue taking Actirfic 1500Mcg/2Ml Injection for as long as your doctor has prescribed. Please do not stop taking Actirfic 1500Mcg/2Ml Injection without consulting your doctor. Do not take Actirfic 1500Mcg/2Ml Injection if you are pregnant or breastfeeding unless prescribed by the doctor. Actirfic 1500Mcg/2Ml Injection should be given to children as advised by your doctor. Keep your doctor informed about your present and past medical history and ongoing medicines to rule out any side effects.

Uses of Actirfic 1500Mcg/2Ml Injection

Treatment of Peripheral neuropathy and megaloblastic anaemia

Medicinal Benefits

Mecobalamin (Methylcobalamin) is a coenzyme form of vitamin B12. It regulates body functions, such as cell multiplication, blood formation, and protein synthesis. It is also used in the treatment of alcoholic neuropathy, pernicious anaemia (red blood cells are not produced due to Vitamin B12 deficiency), diabetic neuropathy (nerve damage due to high blood sugar levels), and multiple sclerosis (immune system disease affecting the brain).

Directions for Use

Actirfic 1500Mcg/2Ml Injection will be administered by a qualified healthcare professional. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Actirfic 1500Mcg/2Ml Injection

  • Painfulness or tenderness at the injection site
  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Headache

Drug Warnings

Do not consume Actirfic 1500Mcg/2Ml Injection if you are allergic to any ingredients in Actirfic 1500Mcg/2Ml Injection. To treat your condition effectually, continue taking Actirfic 1500Mcg/2Ml Injection for as long as your doctor has prescribed. Please do not stop taking Actirfic 1500Mcg/2Ml Injection without consulting your doctor. Do not take Actirfic 1500Mcg/2Ml Injection if you are pregnant or breastfeeding unless prescribed by the doctor. Actirfic 1500Mcg/2Ml Injection should be given to children as advised by your doctor. Inform your doctor if you have low potassium levels in the blood, iron or folic acid deficiency, or if you have had optic nerve damage. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug Interactions

Drug-Drug Interactions: Actirfic 1500Mcg/2Ml Injection may interact with the anti-mycobacterial agent (e.g. aminosalicylic acid), certain anticancer medications (e.g. arsenic trioxide), and certain antibiotics (e.g. chloramphenicol)

Drug-Food Interactions: Avoid using large amounts of alcohol.

Drug-Disease Interactions: Actirfic 1500Mcg/2Ml Injection may interact with disease conditions, including hypokalaemia, optic nerve, malabsorption, and renal impairment.

Drug-Drug Interactions Checker List

  • AMINOSALICYLIC ACID
  • ARSENIC TRIOXIDE
  • CHLORAMPHENICOL

Habit Forming

No

Diet & Lifestyle Advise

  • Take fresh fruits and vegetables into your diet.

  • Eat fortified cereals in your diet.

  • Drink milk and make cheese and yoghurt in your diet.

  • Take eggs, meat, and fish into your diet.

  • Avoid oily and canned foods.

  • Avoid tea and coffee.

  • Quit smoking and avoid drinking alcohol.

Disease/Condition Glossary

Vitamins play an important role in our body. If your body cannot absorb enough vitamins and minerals, that can lead to neurological problems, bone abnormalities, and blood clotting problems. Symptoms like brittle hair and nails, mouth ulcers or cracks in the corners of the mouth, bleeding gums, poor night vision and white growths on the eyes, and neuropathic pain are associated with vitamin deficiency.

Peripheral neuropathy: The deficiency of vitamin B-12 is one cause of peripheral neuropathy. If it is left untreated, it can lead to permanent nerve damage. Peripheral neuropathy is when the nerves that transport messages to and from the brain and spinal cord and to the rest of the body might be damaged or diseased.

Megaloblastic anaemia: Megaloblastic anaemia is a blood disorder in which the number of red blood cells is lower than the normal level. Red blood cells help in transporting oxygen throughout the body. Tissues and organs will not get enough oxygen when your body lacks red blood cells. In megaloblastic anaemia, the red blood cells will be larger than normal, so they are not produced properly. Also, they may not be able to exit the bone marrow into the bloodstream. Megaloblastic anaemia is also known as vitamin B-12 or folate deficiency anaemia.

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Alcohol

Caution

Alcohol does not affect the results of Actirfic 1500Mcg/2Ml Injection. However, excessive alcohol consumption regularly can result in folate-deficient anaemia.

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Pregnancy

Caution

Actirfic 1500Mcg/2Ml Injection may be unsafe to take during pregnancy. If you are pregnant, inform your doctor before taking this medicine. Your doctor may prescribe Actirfic 1500Mcg/2Ml Injection if the benefits outweigh the risks.

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Breast Feeding

Caution

Actirfic 1500Mcg/2Ml Injection is considered safe to be used in breastfeeding. However, if you are breastfeeding, inform your doctor before taking Actirfic 1500Mcg/2Ml Injection.

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Driving

Safe if prescribed

Actirfic 1500Mcg/2Ml Injection does not impact an ability to drive or operate capabilities.

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Liver

Caution

Actirfic 1500Mcg/2Ml Injection should administer with caution in patients with severe liver disease. If you have liver problems, inform your doctor before taking Actirfic 1500Mcg/2Ml Injection. Your doctor may adjust the dose of this medicine based on your condition.

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Kidney

Caution

Actirfic 1500Mcg/2Ml Injection should administer with caution in patients with kidney disease. If you have kidney problems, inform your doctor before taking Actirfic 1500Mcg/2Ml Injection. Your doctor may adjust the dose of this medicine based on your condition.

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Children

Caution

Actirfic 1500Mcg/2Ml Injection can be prescribed for children below 12 years, but your doctor made dose adjustments.

Country of origin

INDIA

Manufacturer/Marketer address

Sri Sai Teja Enclave, Ananth Nagar, Electronic City, Bangalore
Other Info - ACT0552

Author Details

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FAQs

Actirfic 1500Mcg/2Ml Injection belongs to the Vitamins class, primarily used to treat peripheral neuropathies and megaloblastic anaemia caused by vitamin B12 deficiency. Vitamin B12 is a vital dietary nutrient, and deficiency of vitamin B12 can lead to peripheral neuropathy, megaloblastic anaemia, and many other severe conditions.
Mecobalamin is a synthetic form of vitamin B12. It works by increasing vitamin B12 levels in your body, assisting in the treatment of anaemias and nerve problems.
Pain, swelling, or itchy skin where your injection was administered; these symptoms are often minimal and should last only a few hours. If the discomfort is affecting you, you might seek a healthcare expert for a mild pain reliever.
When your vitamin B12 (Mecobalamin) blood levels return to normal, you may be able to discontinue taking Mecobalamin. However, if your diet lacks vitamin B12 or you cannot absorb enough vitamin B12 from food, you may need to take it for the rest of your life.
Vitamin B12 deficiency occurs when you don't have enough Methylcobalamin or Mecobalamin levels in the body. You can include natural Vitamin B12 sources like eggs, beef, liver, chicken, trout, salmon, tuna, fish, clams, fortified breakfast cereal, low-fat milk, yoghurt, and cheese in your diet to treat the deficiency. If you still have low levels of B12, please consult your doctor.
Diarrhoea might be a side-effect of Actirfic 1500Mcg/2Ml Injection. Drink lots of fluids and eat food rich in fibre. If you find blood in your stools (tarry stools) or if you experience excess diarrhoea, consult your doctor.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Actirfic 1500Mcg/2Ml Injection belongs to the class of vitamins used to treat peripheral neuropathies and megaloblastic anaemia. This medicine contains Mecobalamin, a form of vitamin B12 which helps protect the nerves from damage and promotes blood cell production.
You may need more vitamin B12 in your diet due to various reasons. Vitamin B12 is primarily found in animal-based foods, so vegetarians and vegans may need help to get enough. Digestive issues, ageing, gastrointestinal surgery, and certain medications can also lead to malabsorption. Additionally, inadequate dietary intake or increased requirements due to pregnancy, breastfeeding, or medical conditions can contribute to vitamin B12 deficiency. If you're concerned, consult a healthcare professional or registered dietitian to determine the best approach for your individual needs.
If you have a vitamin B12 deficiency, you may experience a range of symptoms, including fatigue and weakness, shortness of breath, pale skin, headaches, dizziness, numbness or tingling in hands and feet, digestive issues like diarrhoea or constipation, mood changes like depression or anxiety, and memory loss or cognitive impairment. If left untreated, vitamin B12 deficiency can lead to more severe health problems, such as anaemia, nerve damage (peripheral neuropathy), increased risk of cardiovascular disease, increased risk of neurological disorders like multiple sclerosis, and increased risk of birth defects if pregnant. It is essential to consult a healthcare professional for a proper diagnosis and treatment plan to manage the deficiency and related symptoms.
Actirfic 1500Mcg/2Ml Injection is a safe and effective treatment option when used properly and under medical supervision. It has a well-established safety profile, and most people tolerate it well. While some mild side effects may occur, they are usually temporary and resolve on their own. Serious side effects are rare; your healthcare professional will closely monitor you to minimize potential risks. With proper administration and dosing, Mecobalamin Injection can help effectively manage vitamin B12 deficiency and related conditions.
A healthcare professional should give Actirfic 1500Mcg/2Ml Injection in a clinical setting. It's usually injected into a muscle or vein, typically in the buttock, thigh, or arm.
When giving a Actirfic 1500Mcg/2Ml Injection, following some simple steps to ensure safe and effective use is essential. Use clean equipment to avoid infection, and always check the injection site for any signs of problems. Use a new needle and syringe each time, and be careful to avoid injecting into blood vessels or nerves. Also, remember to rotate the injection site to minimize discomfort. Finally, watch for any signs of an allergic reaction. By following these easy steps, you can help ensure the safe and effective use of the injection.
Actirfic 1500Mcg/2Ml Injection contains Mecobalamin, a form of vitamin B12.
Actirfic 1500Mcg/2Ml Injection replenishes vitamin B12 in the body, supporting the production of red blood cells, nerve cells, and energy. This helps restore levels and promote overall health and well-being.
The doctor will assess your medical condition and decide whether an oral supplement or a parenteral (injectable) form of Mecobalamin, such as Actirfic 1500Mcg/2Ml Injection, best suits you. They will consider factors such as the severity of your deficiency, your ability to absorb nutrients, and any underlying health conditions you may have.
Common side effects of Actirfic 1500Mcg/2Ml Injection may include pain, itching, swelling or redness around the injection site, nausea, vomiting, diarrhoea, and headache. Most of these side effects do not require medical attention and resolve gradually over time.
Before starting any new medication, including Actirfic 1500Mcg/2Ml Injection, it's essential to inform your doctor about your medical history, allergies, and current medications. This includes sharing information about liver or kidney disease, pregnancy or breastfeeding, and other health conditions. This helps your doctor determine if the medication is safe for you to use and monitor you for any potential side effects.
To ensure safe and effective treatment, you must tell your doctor about all medications you're currently taking, including over-the-counter drugs and supplements. This is because medications can interact with each other, impacting their absorption or effectiveness. Your doctor may need to adjust the dosage or monitoring schedule to avoid potential interactions. Sharing your full medication list can help your doctor provide the best possible care.
Actirfic 1500Mcg/2Ml Injection should be stored in a cool, dry place away from sunlight. Keep out of sight and reach of children.

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