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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:37 PM IST
Zyara 40mg Injection belongs to the class of proton pump inhibitors. It is used in the treatment of Gastro-oesophageal reflux disease (GERD), duodenal/gastric ulcers, Zollinger-Ellison syndrome, heartburn, and erosive oesophagitis. It contains pantoprazole, which helps decrease the amount of acid in the stomach. Some of the common side effects include headache, dizziness, diarrhoea, nausea, vomiting, stomach pain, gas, joint pain, pain, redness, and injection site reactions.
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Manufacturer/Marketer

Ambrons Pharma Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Zyara 40mg Injection

Zyara 40mg Injection is a proton pump inhibitor, primarily used to treat gastro-oesophageal reflux disease (GERD), heartburn, erosive oesophagitis (acid-related damage to the oesophagus lining), Zollinger-Ellison syndrome and other conditions caused due to excessive acid in the stomach. GERD is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers.

Zyara 40mg Injection contains Pantoprazole. It blocks the action of the gastric proton pump that is responsible for the production of acid in the stomach. This reduces the amount of acid produced, heals the ulcers, and prevents the formation of new ulcers. 

Zyara 40mg Injection will be administered by a healthcare professional. Common side effects of Zyara 40mg Injection include headache, dizziness, diarrhoea, nausea, vomiting, stomach pain, gas, joint pain, pain, redness, and swelling at the injection site. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor's advice.

Let your doctor know if you are sensitive or allergic to Zyara 40mg Injection or other medications. Before using Zyara 40mg Injection, let your doctor know if you have any liver, kidney or heart diseases and gastrointestinal problems. Pregnant and breastfeeding women should consult their doctor before using Zyara 40mg Injection. Zyara 40mg Injection may cause dizziness; hence drive or operate machinery only when you are alert. Avoid alcohol intake while using Zyara 40mg Injection since it can increase acid production in the stomach. Zyara 40mg Injection is not recommended for children below five years of age.

Uses of Zyara 40mg Injection

Treatment of Stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn, erosive oesophagitis, and Zollinger-Ellison syndrome

Medicinal Benefits

Zyara 40mg Injection contains Pantoprazole, which is a proton pump inhibitor. It blocks the action of the gastric proton pump that is responsible for the production of acid in the stomach. This reduces the amount of acid produced, heals the ulcers, and prevents the formation of new ulcers. It also relieves the symptoms of GERD like heartburn, difficulty in swallowing, and persistent cough. Pantoprazole may also prevent oesophageal cancer.

Directions for Use

Zyara 40mg Injection will be injected by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zyara 40mg Injection

  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Diarrhoea
  • Stomach pain
  • Gas
  • Joint pain
  • Pain, redness, and swelling at the injection site.

Drug Warnings

Let your doctor know if you are sensitive to any of the components in Zyara 40mg Injection. Zyara 40mg Injection should be used with caution and only under a doctor’s supervision if you have stomach/intestinal problems, liver, kidney or heart diseases, recent abdominal surgery, risk of bone fractures, and autoimmune diseases like lupus. Long term treatment with Zyara 40mg Injection may increase the risk of fractures of the hip, spine, and wrist. Hence, inform your doctor if you have osteoporosis and bone-related problems. Zyara 40mg Injection may also cause low Vitamin B12 levels on long term usage. Hence let your doctor know if you have Vitamin B12 deficiency before starting Zyara 40mg Injection. Let your doctor know if you are pregnant or a nursing mother before starting Zyara 40mg Injection. Zyara 40mg Injection may cause dizziness; hence drive or operate machinery only when you are alert. Avoid alcohol intake while using Zyara 40mg Injection since it can increase acid production in the stomach. Zyara 40mg Injection is recommended for children above five years of age only when prescribed by a doctor.

Drug Interactions

Drug-Drug Interaction: Zyara 40mg Injection may interact with anti-HIV (atazanavir), antifungals (ketoconazole, itraconazole), anti-cancer drugs (methotrexate), heart-related medicines (digoxin), and water pills.

Drug-Food Interaction: Avoid fatty foods, alcohol, caffeine, and other triggering foods that can worsen your gastrointestinal problems.

Drug-Disease Interaction: Brief your medical history to the doctor if you have stomach/intestinal problems, liver, kidney or heart diseases, recent abdominal surgery, risk of bone fractures, autoimmune diseases like lupus, and Vitamin B12 deficiency before starting Zyara 40mg Injection.

Drug-Drug Interactions Checker List

  • ATAZANAVIR
  • KETOCONAZOLE
  • ITRACONAZOLE
  • METHOTREXATE
  • DIGOXIN

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.

  • Limit taking high fibre foods, foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods. 

  • Do not have large meals at a time; instead try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.

  • Practice yoga and recreation techniques to manage your emotional stress.

  • If you are lactose intolerant, avoid using dairy products since it can worsen your stomach discomfort.

  • If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.

  • Drink plenty of fluids to prevent dehydration.

Special Advise

  • Your doctor may suggest diagnostic procedures like endoscopy or colonoscopy to understand your condition and its severity.

  • Zyara 40mg Injection may interfere with urine tests for tetrahydrocannabinol-THC and blood tests to find certain tumours. Inform your doctor and laboratory staff that you are taking Zyara 40mg Injection before undergoing examinations.

Disease/Condition Glossary

Acidity: The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity, GERD, heartburn, stomach ulcer, and Zollinger Ellison syndrome.

Gastroesophageal reflux disease (GERD): It is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms of GERD include chest pain, difficulty swallowing, regurgitation (expulsion of food from the pharynx or oesophagus) of food/sour liquid, and a burning sensation in the chest.

Zollinger Ellison syndrome: It is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers. Symptoms include abdominal pain, diarrhoea, heartburn, acid reflux, and burping.

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Alcohol

Unsafe

Alcohol consumption may increase acid production in the stomach. It is advised to avoid alcohol intake to prevent any undesirable side effects of Zyara 40mg Injection and further worsening of your condition.

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Pregnancy

Caution

It is advised to consult your doctor if you plan to conceive or are already pregnant before starting Zyara 40mg Injection.

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Breast Feeding

Caution

It is not known if Zyara 40mg Injection passes into breast milk. Please consult your doctor before taking Zyara 40mg Injection if you are a nursing mother.

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Driving

Caution

Zyara 40mg Injection may cause dizziness; hence drive or operate machinery only when you are alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Zyara 40mg Injection.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Zyara 40mg Injection.

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Children

Caution

Zyara 40mg Injection is recommended for children above five years of age only when prescribed by a doctor.

Country of origin

India
Other Info - ZY15866

Author Details

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FAQs

Zyara 40mg Injection is used to treat stomach ulcers, gastro-oesophageal reflux disease (GERD), heartburn, erosive oesophagitis, and Zollinger-Ellison syndrome.
Zyara 40mg Injection works by reducing the amount of acid produced in the stomach and thus relieves stomach ulcers, heartburn, GERD, and other gastrointestinal discomforts.
Please do not take Zyara 40mg Injection for longer durations unless prescribed by the doctor. Taking Zyara 40mg Injection on long-term may cause you to develop stomach growths known as fundic gland polyps. A regular check-up is advised if Zyara 40mg Injection is prescribed for longer durations.
Zyara 40mg Injection may cause bloating as a side effect with its regular use. You may experience tightness, fullness, or swelling of your stomach area. It is advised to avoid consuming wind/gas-producing foods like beans, onions, lactose-containing foods, and carbonated beverages. You can also try herbal teas like peppermint, coriander, fennel, turmeric, and chamomile. If you do not notice any improvement in your bloating, please seek medical advice.
Diarrhoea might be a side-effect of Zyara 40mg Injection. Drink lots of fluids and eat non-spicy foods if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excess diarrhoea, consult your doctor. Prolonged intake of proton pump inhibitors like Zyara 40mg Injection is linked with a greater risk of Clostridium difficile-associated diarrhoea. If you develop diarrhoea that does not improve, immediately consult a doctor.
On long term treatment, Zyara 40mg Injection may increase the risk of fractures of the hip, spine, and wrist. Inform your doctor if you have osteoporosis, bone-related problems, or take any corticosteroids. Your doctor may suggest supplements like Calcium citrate and Vitamin D.
Zyara 40mg Injection may cause low Vitamin B12 levels on long term usage. Your doctor may adjust the dose of Zyara 40mg Injection accordingly and may suggest Vitamin B12 supplements if you are on long term treatment with Zyara 40mg Injection.
Zyara 40mg Injection should be used with caution and only under a doctor’s supervision if you have any liver, kidney or heart diseases, stomach and intestinal problems, recent abdominal surgery, Vitamin B12 deficiency, risk of bone fractures, osteoporosis, and autoimmune diseases like lupus.

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