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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Nov 23, 2024 | 4:29 PM IST
Zolith 250mg Tablet belongs to the class of antipsychotic medicine used in the treatment of bipolar disorder and mania. This medicine suppresses the excess and abnormal activity of nerve cells in the brain by increasing the activity of chemical messengers in the brain. Common side effects include loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination.
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ORAL

Return Policy

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About Zolith 250mg Tablet

Zolith 250mg Tablet belongs to a psychological class of drugs called 'anti-manic agents' or 'mood stabilizers' primarily used to prevent and treat mood disorders like mania and bipolar disorder. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Bipolar disorder is a mental condition associated with extreme mood swings ranging from the hyper stage of mania to low mood depression.

Zolith 250mg Tablet contains Lithium carbonate that helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.

Take Zolith 250mg Tablet as prescribed. Your doctor will advise you on how often you need to take Zolith 250mg Tablet based on your medical condition. Some people may experience loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination. Most of these side effects of Zolith 250mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Zolith 250mg Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Zolith 250mg Tablet. Regular blood tests are recommended while taking Zolith 250mg Tablet to monitor the levels of lithium in blood. If you have fits, kidney or heart problems, thyroid, persistent headache, vision problems, and if you are planning or had weight loss surgery, please inform your doctor before taking Zolith 250mg Tablet.

Uses of Zolith 250mg Tablet

Treatment of Bipolar disorder and Mania

Medicinal Benefits

Zolith 250mg Tablet is a mood stabilizer that is used to prevent and treat mood disorders such as mania and bipolar disorder. Zolith 250mg Tablet contains Lithium carbonate that helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood. Thus, Zolith 250mg Tablet relaxes nerves and calms the mood, which helps in having a better social life and enables to do daily activities comfortably.

Directions for Use

Take Zolith 250mg Tablet with food for better absorption or take it as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zolith 250mg Tablet

  • Loss of appetite
  • Dizziness
  • Dry mouth
  • Taste change
  • Diarrhoea
  • Blurred vision
  • Slurred speech
  • Shaky movements
  • Increased thirst and urination

Drug Warnings

Regular blood tests are recommended while taking Zolith 250mg Tablet to check lithium levels in the blood. If you are pregnant or breastfeeding, please inform your doctor before taking Zolith 250mg Tablet. If you have hypothyroidism (underactive thyroid gland), please inform your doctor before taking Zolith 250mg Tablet as it may cause low thyroid levels. If you notice decreased amount of urine, dark, reddish urine, muscle pain or weakness, inform your doctor immediately as it may be due to a serious condition called rhabdomyolysis (muscle tissue breakdown) which may lead to kidney problems.

Drug Interactions

Drug-Drug Interaction: Zolith 250mg Tablet may have interaction with high blood pressure-lowering medicines (ramipril, lisinopril, methyldopa, amlodipine, diltiazem), pain killers (ibuprofen, diclofenac, celecoxib, indomethacin), asthma drugs (theophylline), antipsychotics (olanzapine, haloperidol, clozapine, sertindole), fits related drugs (phenytoin, clonazepam, carbamazepine), heart-related medicines (quinidine, amiodarone, propafenone, ranolazine, procainamide, disopyramide, hydroquinidine, ibutilide, sotalol, dofetilide), antidepressants (paroxetine, amitriptyline, fluoxetine), antibiotics (trimethoprim, spectinomycin, metronidazole, tetracycline).

Drug-Food Interaction: Zolith 250mg Tablet may interact with caffeine. Therefore, reduce the intake of caffeine including coffee, tea, or herbal medicines as it may decrease the effect of Zolith 250mg Tablet. Also, avoid alcohol intake as it may increase side effects such as drowsiness, dizziness, or difficulty in concentrating. Intake of sodium may also alter lithium levels. Hence, maintain a constant dietary intake of salt.

Drug-Disease Interaction: If you have fits, kidney or heart problems, thyroid, persistent headache, vision problems, Brugada syndrome (a hereditary syndrome affecting the heart), hypothyroidism (low thyroid levels), and low sodium levels, inform your doctor before taking Zolith 250mg Tablet.

Drug-Drug Interactions Checker List

  • RAMIPRIL
  • LISINOPRIL
  • METHYLDOPA
  • AMLODIPINE
  • DILTIAZEM
  • IBUPROFEN
  • DICLOFENAC
  • CELECOXIB
  • INDOMETHACIN
  • THEOPHYLLINE
  • OLANZAPINE
  • HALOPERIDOL
  • CLOZAPINE
  • SERTINDOLE
  • PHENYTOIN
  • CLONAZEPAM
  • CARBAMAZEPINE
  • QUINIDINE
  • AMIODARONE
  • PROPAFENONE
  • RANOLAZINE
  • PROCAINAMIDE
  • DISOPYRAMIDE
  • HYDROQUINIDINE
  • IBUTILIDE
  • SOTALOL
  • DOFETILIDE
  • PAROXETINE
  • AMITRIPTYLINE
  • FLUOXETINE
  • TRIMETHOPRIM
  • SPECTINOMYCIN
  • METRONIDAZOLE
  • TETRACYCLINE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a constant sodium diet as it may affect lithium levels in the blood and cause adverse effects.
  • Limit the intake of caffeine as it may reduce the effectiveness of Zolith 250mg Tablet.
  • Do regular exercise and maintain a stable weight as Zolith 250mg Tablet may cause weight gain.
  • Drink plenty of water to avoid dehydration and try to drink the same amount of water every day as any major changes in quantity may affect lithium levels.
  • Avoid consumption of alcohol as it may increase drowsiness.

Special Advise

  • Regular blood tests are advised every week while taking Zolith 250mg Tablet to monitor the levels of lithium in blood. When lithium levels are constant, blood tests may be done every 3 months.
  • Drink a constant amount of water daily and maintain a constant sodium intake as any major changes in these two may alter the levels of lithium in blood.

Disease/Condition Glossary

Mania: It is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Mania may occur due to lack of sleep or changes in sleep pattern, high levels of stress, and alcohol intake. Seek medical help immediately if you have any self-harming or suicidal thoughts.

Bipolar disorder: It is also called manic depression, a mental condition associated with extreme mood swings ranging from manic highs to depressive lows. The symptoms of bipolar disorder include mania (high energy and excitability) and depression (loss of interest, hopelessness, and low energy). Bipolar disorder involves lifelong treatment.

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with Zolith 250mg Tablet as it may increase the risk of side effects such as drowsiness, dizziness or difficulty in concentrating.

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Pregnancy

Unsafe

Zolith 250mg Tablet is a Category D pregnancy drug and is not recommended for use during pregnancy as it may cause harm to the unborn baby.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Zolith 250mg Tablet as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Unsafe

Zolith 250mg Tablet may cause dizziness, drowsiness or other severe adverse effects. Therefore, avoid driving if you feel drowsy or dizzy after taking Zolith 250mg Tablet.

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Liver

Safe if prescribed

Zolith 250mg Tablet is safe to use in patients with liver diseases/conditions if prescribed by a doctor.

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Kidney

Caution

Take Zolith 250mg Tablet with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required. Zolith 250mg Tablet is not recommended for patients with severe kidney problems.

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Children

Caution

Zolith 250mg Tablet is generally not recommended for children below 12 years. However, Zolith 250mg Tablet may be used in children above 7 years for treating bipolar disorder only if prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

Plot No-208, Industrial Area, Phase 1, Panchkula-134113
Other Info - ZO20335

Author Details

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FAQs

Zolith 250mg Tablet belongs to a psychological class of drugs called 'anti-manic agents' or 'mood stabilizers' primarily used to prevent and treat mood disorders like mania and bipolar disorder.
Zolith 250mg Tablet helps to treat mental disorders by increasing the activity of chemical messengers in the brain; thereby, suppressing the excessive and abnormal activity of nerve cells in the brain and helping in stabilizing a person’s mood.
Zolith 250mg Tablet is not recommended for hypothyroid (underactive thyroid gland) patients as it may increase the risk of low levels of thyroid hormone. Therefore, if you have hypothyroidism, please inform your doctor before taking Zolith 250mg Tablet.
Zolith 250mg Tablet may cause weight gain but it is not necessary for everyone taking Zolith 250mg Tablet to experience this side effect. However, in order to avoid gaining weight while taking Zolith 250mg Tablet, you are advised to do regular exercise and avoid high-calorie drinks. Instead take non-alcoholic drinks, herbal tea and lemon water.
It is advised to inform your doctor if you are planning or had weight loss surgery as the dose may be adjusted accordingly based on lithium levels in blood.
Zolith 250mg Tablet may cause dehydration especially if you have low sodium levels in the body or consume too much alcohol. However, if you notice dark, strong-smelling urine or a decrease in urination, it indicates that you are dehydrated, and this may affect lithium levels in the blood. Therefore, you are recommended to drink plenty of fluids while taking Zolith 250mg Tablet to avoid dehydration.
You are not recommended to stop taking Zolith 250mg Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Zolith 250mg Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Zolith 250mg Tablet, please consult your doctor so that the dose may be gradually reduced.
You are not recommended to take Zolith 250mg Tablet with fluoxetine or other antidepressants such as paroxetine and sertraline as co-administration of these medicines may increase the risk of a rare and serious condition known as serotonin syndrome. If you experience blurred vision, increased heart rate, hallucination, fits, confusion, muscle stiffness or spasm, vomiting, nausea, diarrhoea, excessive sweating, stomach cramps, fever, shaking, or shivering, please consult a doctor immediately. However, before using Zolith 250mg Tablet with any other medicines, you are advised to contact your doctor.
The effects of Zolith 250mg Tablet can vary from person to person, but it generally takes 1-3 weeks for you to see the full benefits. However, it's important to continue taking the Zolith 250mg Tablet regularly as prescribed by your doctor to maintain its effectiveness.
It's important to inform your doctor about your hypertension and the medications you're taking for it as Zolith 250mg Tablet can interact with certain blood pressure medications, and your doctor may need to adjust your treatment plan to ensure your safety.
No, you should not increase the dose of Zolith 250mg Tablet on your own. It can take 1-3 weeks to feel the full effects, and increasing the dose without medical advice can be dangerous and may lead to adverse effects. However consult your doctor if you have any concerns.
Yes, Zolith 250mg Tablet can cause sleepiness as a side effect. It's important to be cautious when performing activities that require alertness, such as driving or operating heavy machinery, until you know how the medication affects you.
Yes, Zolith 250mg Tablet can affect the kidneys. Long-term use of lithium can lead to kidney problems, and regular monitoring of kidney function is necessary during treatment. It's important to inform your doctor if you have any pre-existing kidney conditions or if you experience any symptoms of kidney problems while taking Zolith 250mg Tablet.
Zolith 250mg Tablet should only be started if adequate facilities for assessing Zolith 250mg Tablet levels are available. Because elevated levels of Zolith 250mg Tablet are linked to Zolith 250mg Tablet toxicity. Zolith 250mg Tablet toxicity can even occur at dose which is effective for treatment. Therefore, your doctor may closely monitor your Zolith 250mg Tablet levels weekly until stabilization is achieved, then weekly for one month and then at monthly intervals thereafter.
Zolith 250mg Tablet should be taken as prescribed by your doctor. It is recommended to take with food to reduce nausea. Zolith 250mg Tablet may be taken before or after meals. Swallow it as a whole with a glass of water. Do not crush, chew or break it.
Certain medications which decrease the levels of Zolith 250mg Tablet in blood include carbonic anhydrase inhibitors, chlorpromazine, sodium-containing preparations, theophylline, urea and herbal medicines. Therefore, before starting Zolith 250mg Tablet, inform your doctor about all the medicines you are taking.
The common side effects of Zolith 250mg Tablet are loss of appetite, dizziness, dry mouth, taste change, diarrhoea, blurred vision, slurred speech, shaky movements, increased thirst, and urination. If any of these side effects persist or worsen, please consult your doctor.

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