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Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 9:32 AM IST

Zidovir Oral Solution is used in the treatment of HIV. It contains Zidovudine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This inhibits viral replication and thereby prevents the further spread of infection. Common side effects of this medication may include nausea, headache, stomach pain, loss of appetite, vomiting, nausea, cough, diarrhoea, nasal congestion, fever, tiredness, muscle pain, dizziness, and allergic reactions.

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Prescription drug

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Composition :

ZIDOVUDINE-50MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Apr-26

About Zidovir Oral Solution

Zidovir Oral Solution is an antiretroviral medicine used in the treatment of HIV. Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Syndrome (AIDS). Symptoms of HIV include fever, chills, night sweats, muscle aches, etc. This medicine is also used for the prevention of maternal-fetal HIV transmission.

Zidovir Oral Solution contains Zidovudine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection.

Zidovir Oral Solution may cause certain side effects such as nausea, headache, stomach pain, loss of appetite, vomiting, nausea, cough, diarrhea, nasal congestion, fever, tiredness, muscle pain, dizziness, and allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. Zidovir Oral Solution should be taken as advised by your doctor. Your doctor will decide the dose of the medicine based on your health condition. Do not take more than the recommended dose.

Zidovir Oral Solution should be avoided if you are allergic to it. Before taking this medicine, inform your doctor if you have heart problems, liver/kidney diseases, haematological toxicity, severe anemia, hepatomegaly with steatosis, lactic acidosis, or peripheral nephropathy. If you are pregnant and breastfeeding, let your doctor know before taking Zidovir Oral Solution . Zidovir Oral Solution can be used in children only if recommended by the doctor. If prescribed, the child should be carefully monitored for any changes. Zidovir Oral Solution is used to treat the infection but does not cure or prevent it. Inform your doctor about your medical history and the medicines you take to prevent possible interactions.

Uses of Zidovir Oral Solution

Zidovir Oral Solution is used in the treatment of HIV Infection

Medicinal Benefits

Zidovir Oral Solution contains Zidovudine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection. Zidovir Oral Solution is used in combination with other antiretroviral medicines to help reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV. 

Side Effects of Zidovir Oral Solution

  • Nausea
  • Abdominal pain
  • Vomiting
  • Dizziness
  • Back pain
  • Loss of appetite
  • Tiredness
  • Nasal congestion
  • Fever
  • Cough

Directions for Use

Tablet/Capsule: Take this medicine as advised by your doctor. It should be taken without food at least 2 hours before the meal. Swallow as a whole with a glass of water. Do not chew, crush or break the medicine.Suspension: Take it as prescribed by your doctor. Shake the container well before each use. Measure and consume the required amount using a measuring cup. It is advised not to consume more than the recommended dose of medicine.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Zidovir Oral Solution should be avoided if you are allergic to it. It is advised not to take this medicine along with ganciclovir, interferon alpha, ritonavir, stavudine, daunorubicin, bleomycin, idarubicin, and epirubicin, as it can cause serious side effects. Hence, avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, hematological toxicity, anemia, hepatomegaly with steatosis, lactic Acidosis, and peripheral nephropathy, on priority. It is not known whether Zidovir Oral Solution can be given to pregnant and breastfeeding women. Hence, inform your doctor if you are pregnant and breastfeeding before receiving Zidovir Oral Solution . Zidovir Oral Solution can be used in children only if recommended by the pediatrician. If prescribed, the child should be carefully monitored for any changes. Zidovir Oral Solution is used to treat the infection but does not cure or prevent it. Zidovir Oral Solution is used to treat the infection but does not cure or prevent it. This medicine is used in combination for the treatment of HIV infection. This medicine may cause dizziness; hence, avoid driving or operating machines while taking Zidovir Oral Solution .

Therapeutic Class

ANTIRETROVIRAL AGENTS

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin-rich and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration.

Habit Forming

No

How Zidovir Oral Solution Works

Zidovir Oral Solution contains Zidovudine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection.

What if I have taken an overdose of Zidovir Oral Solution

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Zidovir Oral Solution may include extreme drowsiness/tiredness, confusion, and seizures. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.
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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Hence, avoid alcohol consumption while taking Zidovir Oral Solution .

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Pregnancy

Consult your doctor

If you are pregnant or suspect you may be pregnant, inform your doctor before taking Zidovir Oral Solution . Your doctor will prescribe a suitable dose of this medicine to prevent maternal-fetal HIV transmission.

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Breast Feeding

Unsafe

Zidovir Oral Solution is excreted in milk. You should not nurse your child if you are taking this medicine because of the risk of HIV-1 transmission and serious adverse reactions in breastfeeding infants.

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Driving

Unsafe

Avoid driving vehicles after taking Zidovir Oral Solution as it may cause dizziness and affect your ability to drive.

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Liver

Caution

Zidovir Oral Solution should be used with caution in patients with mild to moderate liver impairment. In case of severe liver problems, it may increase the risk of hematologic toxicity. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Zidovir Oral Solution should be used with caution in patients with kidney impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Safe if prescribed

Please consult your doctor. Your doctor will decide the dose of this medicine based on the age and condition of your child.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - ZID0003

Author Details

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FAQs

Zidovir Oral Solution is used to treat HIV infection.
Zidovir Oral Solution contains Zidovudine, which works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection.
No, completing the entire treatment course prescribed by the doctor is always recommended. Sudden discontinuation of the medicine can lead to serious side effects. Your doctor will decide whether to stop the medication or not.
Zidovir Oral Solution does not cure HIV infection. However, it helps to control the disease and prevent opportunistic infections.
Zidovir Oral Solution is an antiretroviral medication used to treat HIV. It belongs to the class of nucleoside reverse transcriptase inhibitors (NRTIs) that work by blocking the reverse transcriptase enzyme needed for the virus to replicate its DNA, thereby inhibiting viral replication and preventing the spread of infection.
Yes, Zidovir Oral Solution is safe if taken in the dose and duration exactly as prescribed by the doctor.
Zidovir Oral Solution should be taken orally. Swallow it as a whole with a glass of water. Do not chew, crush or break it. It should be taken on an empty stomach at least 2 hours before the meals.
Yes, Zidovir Oral Solution is effective in the treatment of HIV when used as part of a combination antiretroviral therapy. They help reduce the viral load and prevent the progression of HIV to AIDS. However, the effectiveness of Zidovir Oral Solution depends on consistently following the prescribed dosage and timing as directed by the doctor.
If you forget to take a dose of Zidovir Oral Solution , take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not double the dose.
The side effects of Zidovir Oral Solution include dizziness, headache, stomach pain, loss of appetite, vomiting, nausea, cough, diarrhoea, nasal congestion, fever, tiredness, muscle pain, and allergic reactions. Consult the doctor if any of these side effects persist or worsen.

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