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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:20 PM IST

Zelgor 500 mg Tablet is an anti-androgen medicine used to treat prostate cancer. It contains Abiraterone, which is in a class of medications called androgen biosynthesis inhibitors. It works by decreasing the amount of certain hormones in the body. Common side effects of Zelgor 500 mg Tablet may include nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite, and groin pain.

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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Zelgor 500 mg Tablet

Zelgor 500 mg Tablet is an anti-androgen medicine used in the treatment of prostate cancer. It is used to treat metastatic castration-resistant prostate cancer (a condition where cancer does not get controlled with hormonal therapy) and metastatic castration-sensitive prostate cancer (a condition where cancer has spread to other parts of the body but can be controlled) in men. Prostate cancer is a condition that occurs when the prostate gland cells increase abnormally. Symptoms may include difficulty in urinating, pain, numbness, etc.

Zelgor 500 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. Zelgor 500 mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. 

Zelgor 500 mg Tablet may cause certain side effects such as nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite and groin pain. These side effects usually disappear without any medical attention. However, if these side effects persist, inform your doctor. Take this medicine as advised by your doctor. It should be taken on an empty stomach at least 2 hours before or after meals. Your doctor will decide the dose of the medicine based on the severity of your disease.

Zelgor 500 mg Tablet should be avoided if you are allergic to it. Inform your doctor if you have any pre-existing or a history of liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention before taking Zelgor 500 mg Tablet . Zelgor 500 mg Tablet is not recommended for use in women and children as the safety and efficacy of this medicine are not established. Inform your doctor of all your ongoing medications to avoid interactions. This medicine is used in combination with prednisolone for the treatment of prostate cancer. 

Uses of Zelgor 500 mg Tablet

Treatment of Prostate Cancer

Medicinal Benefits

Zelgor 500 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes increase of cancer cells in prostate gland. Zelgor 500 mg Tablet works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. Zelgor 500 mg Tablet is used in combination with prednisolone for the treatment of prostate cancer. It is mainly intended for use in men only.

Directions for Use

Zelgor 500 mg Tablet should be taken on an empty stomach at least two hours before or after a meal. It is advised not to take more than the recommended dose of medicine. Swallow the medicine as a whole with a glass of water. Do not chew or crush or break the medicine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zelgor 500 mg Tablet

  • Dizziness
  • Heartburn
  • Headache
  • Diarrhoea
  • Muscle Weakness
  • Joint Pain
  • Confusion
  • Hot Flushes
  • Loss of Appetite
  • Groin Pain

Drug Warnings

Zelgor 500 mg Tablet should be avoided if you are allergic to it or any other components present in it. Inform your doctor if you have/had any conditions like liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention or taking any other medicines before taking Zelgor 500 mg Tablet as it may cause serious side effects. Zelgor 500 mg Tablet is not recommended for use in women and children as the safety and efficacy of this medicine are not established. This medicine is used in combination with prednisolone for the treatment of prostate cancer.

Drug Interactions

Drug-drug interactions: Zelgor 500 mg Tablet may interact with CYP3A4 Inducers (phenytoin, phenobarbital), CYP2D6 Substrates (Flecainide, Venlafaxine), antifungal medicine (ketoconazole, itraconazole), and many other medicines.

Drug-food interactions: No interactions found. 

Drug-disease interactions: Zelgor 500 mg Tablet should be used with caution in patients with severe liver and kidney failure, adrenal or pituitary gland problems, heart failure, an irregular heartbeat, increased blood pressure, adrenocortical insufficiency, and hypoglycemia.

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • PHENYTOIN
  • PHENOBARBITAL
  • FLECAINIDE
  • VENLAFAXINE

Habit Forming

No

Diet & Lifestyle Advise

  • Try to take vegetables like cauliflower, cabbage, broccoli, spinach and kale. This food slows the growth of prostate cancer and even reduces the risk of prostate cancer.
  • It is advised to consume fewer dairy products as these foods may increase the risk of prostate cancer. 
  • Physical activity helps in strengthening muscles, reduces fatigue, helps in weight loss and gives strength.
  • Maintain a healthy weight by doing regular simple exercises and yoga. 
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention. 
  • Avoid including red meat high amounts of meat in your diet. When meat is cooked, it may increase the risk of developing prostate cancer.

Special Advise

  • Zelgor 500 mg Tablet is not recommended for use in patients suffering from severe hepatotoxicity.
  • This medicine may cause laboratory abnormalities like elevated alkaline phosphatase, hypercholesterolemia, hyperglycemia, and hypokalemia.
  • It is also advised to perform frequent checkups on your potassium, blood sugar, and blood pressure levels.

Disease/Condition Glossary

Prostate cancer: The prostate gland is a small walnut-sized gland present under the bladder which is responsible for the production of seminal fluid. Prostate cancer is a carcinogenic condition that occurs when the cells of the prostate gland increase out of control. The main cause of this condition is unknown. However, a few underlying reasons that increase the risk for this condition include age, family history, ethnic group, genetic factors, obesity, etc.

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Alcohol

Caution

Interaction of Zelgor 500 mg Tablet with alcohol is unknown. It is advisable to consult your doctor if you have concerns.

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Pregnancy

Not applicable

Not intended for women.

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Breast Feeding

Not applicable

Not intended for women.

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Driving

Caution

Zelgor 500 mg Tablet may decrease alertness or make you feel sleepy and dizzy. So, do not drive or operate heavy machinery while taking Zelgor 500 mg Tablet until your vision improves.

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Liver

Caution

Zelgor 500 mg Tablet should be used with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose based on your condition.

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Kidney

Caution

Zelgor 500 mg Tablet should be used with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust the dose based on your condition.

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Children

Unsafe

Zelgor 500 mg Tablet is not recommended for use in children as the safety and efficacy of this medicine are not established.

Country of origin

INDIA

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - ZEL0046

FAQs

Zelgor 500 mg Tablet is used to treat Prostate Cancer.
Zelgor 500 mg Tablet contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. It works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.
No, do not stop taking Zelgor 500 mg Tablet without consulting your doctor. It is recommended to take this medicine for the entire prescribed duration, even when symptoms improve or resolve.
The common side-effects of Zelgor 500 mg Tablet are nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite, and groin pain. These side effects usually do not require any medical attention.
Take Zelgor 500 mg Tablet as advised by your doctor. However, if you forget or miss any dose of Zelgor 500 mg Tablet , take it as soon as you remember unless it is time for your next dose. But do not double the dose.
Inform your doctor if you have a pre-existing or a history of liver/kidney disease, hypoglycemia, hypokalemia, bone disorders, adrenocortical insufficiency, fluid retention and cardiovascular conditions before taking Zelgor 500 mg Tablet .
Zelgor 500 mg Tablet is not a cure for prostate cancer. However, it helps manage advanced stages by blocking testosterone production, thereby slowing the growth and progression of the cancer.
No, Zelgor 500 mg Tablet is not a chemotherapy drug. Zelgor 500 mg Tablet is a hormonal therapy that lowers testosterone levels to reduce the growth of prostate cancer.
You need to take prednisolone with Zelgor 500 mg Tablet to reduce the risk of high blood pressure, fluid retention (too much water in your body), and low potassium levels in your blood which may be caused by Zelgor 500 mg Tablet .
Yes, Zelgor 500 mg Tablet can affect the liver. Your healthcare provider will perform blood tests to check your liver function before and during treatment.
Liver function tests (investigation) should be conducted before starting Zelgor 500 mg Tablet and periodically during treatment, as advised by your healthcare provider.
Zelgor 500 mg Tablet should be taken once daily on an empty stomach, at least two hours after eating or one hour before eating. Swallow Zelgor 500 mg Tablet whole with a glass of water; do not chew, crush, or break it. Always follow the recommended dose.

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