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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Zedex-P Cold Syrup is used to treat cough. It works by reducing cough receptor activity, making sputum less viscous and relieving congestion and throat irritation. In some cases, this medicine may cause side effects such as nausea, diarrhoea, bloating, indigestion, vomiting, stomach upset, sweating, dizziness, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Wockhardt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Zedex-P Cold Syrup

Zedex-P Cold Syrup belongs to a class of respiratory medications called 'expectorant' primarily used to treat cough. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus or smoke) from the airways. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce thick mucus, while a chesty cough (wet cough) produces mucous or sputum that helps clear the airways.

Zedex-P Cold Syrup consists of four medicines, namely: Bromhexine (mucolytic), Dextromethorphan (cough suppressant), Phenylephrine (decongestant), and Menthol (Coolant). Bromhexine makes sputum less viscous and makes it easier to cough out. Dextromethorphan relieves cough by reducing cough receptor activity, thereby affecting signals in the brain that trigger the cough reflex. Phenylephrine helps shrink the blood vessels in the nostrils and the passage and reduces stuffy noses. Menthol produces a cooling sensation and relieves throat irritation.

Zedex-P Cold Syrup should be taken as prescribed by the doctor. Some people may experience nausea, diarrhoea, bloating, indigestion, vomiting, stomach upset, sweating, dizziness, headache, and skin rash. Most of these side effects of Zedex-P Cold Syrup do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use Zedex-P Cold Syrup if you are allergic to any components present in it. Brief your medical history to the doctor if you have any heart, liver, kidney, lung diseases, depression and Parkinson's disease before taking Zedex-P Cold Syrup. Zedex-P Cold Syrup can cause sleepiness; hence avoid taking alcohol while using Zedex-P Cold Syrup. Zedex-P Cold Syrup may affect your ability to drive. It is advised not to drive whilst taking this medicine. Check with your doctor if you are pregnant, breastfeeding, or taking other prescribed or non-prescribed drugs.

Uses of Zedex-P Cold Syrup

Treatment of Cough

Medicinal Benefits

Zedex-P Cold Syrup belongs to a class of medication called 'expectorants,' containing four medicines, namely: Bromhexine (mucolytic), Dextromethorphan (cough suppressant), Phenylephrine (decongestant), Menthol (Coolant). Bromhexine makes sputum less viscous and makes it easier to cough out. Dextromethorphan relieves cough by reducing cough receptor activity, thereby affecting signals in the brain that trigger the cough reflex. Phenylephrine helps shrink the blood vessels in the nostrils and the passage and reduces stuffy nose. Menthol produces a cooling sensation and relieves throat irritation.

Directions for Use

Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zedex-P Cold Syrup

  • Nausea
  • Diarrhoea
  • Bloating
  • Indigestion
  • Vomiting
  • Stomach upset
  • Sweating
  • Dizziness
  • Headache
  • Skin rash

Drug Warnings

Zedex-P Cold Syrup should be used with caution in patients with heart, liver, kidney diseases, depression, and Parkinson's disease. Anti-tussive agents like Dextromethorphan can cause withdrawal symptoms like restlessness, difficulty sleeping, irritability, anxiety, feeling your heartbeat (palpitations), increased blood pressure, feeling or being sick, diarrhoea, shaking, shivering or sweating. If you feel like you need to take the Dextromethorphan containing Zedex-P Cold Syrup though you feel well, it can be a symptom of addiction to Zedex-P Cold Syrup. Please consult your doctor if you notice any addiction symptoms. Zedex-P Cold Syrup is not recommended for stomach ulcer use since mucolytics like Bromohexine may disrupt the gastric mucosal barrier; therefore cautiously administered in patients with a stomach ulcer. Avoid consuming alcohol along with Zedex-P Cold Syrup as it could lead to increased drowsiness or dizziness. Drive only if you are alert since Zedex-P Cold Syrup may cause sleepiness/shakiness/increased heart rate in some people.

Drug Interactions

Drug-Drug Interactions: Zedex-P Cold Syrup may interact with central nervous system stimulants (dextroamphetamine, amphetamine), anti-depressants (duloxetine, escitalopram, quetiapine, sertraline, isocarboxazid, selegiline, phenelzine, rasagiline, tranylcypromine), alcohol (ethanol), anti-allergic drugs (diphenhydramine), pain medicine (codeine), fits drugs (pregabalin), heart-related drugs (quinidine), anxiety treating drugs (alprazolam) and staining agents (methylene blue).

Drug-Food Interactions: Limit alcohol intake since it may worsen the side effects like dizziness and shakiness.

Drug-Disease Interactions: Brief your medical history if you have any heart, liver, or kidney diseases, stomach ulcers, inflammation of air passages, lung disorders, difficulty breathing, severe asthma, depression, or Parkinson's disease before taking Zedex-P Cold Syrup.

Drug-Drug Interactions Checker List

  • DEXTROAMPHETAMINE
  • AMPHETAMINE
  • DULOXETINE
  • ESCITALOPRAM
  • QUETIAPINE
  • SERTRALINE
  • ISOCARBOXAZID
  • SELEGILINE
  • PHENELZINE
  • RASAGILINE
  • TRANYLCYPROMINE
  • ETHANOL
  • DIPHENHYDRAMINE
  • CODEINE
  • PREGABALIN
  • QUINIDINE
  • ALPRAZOLAM
  • METHYLENE BLUE

Habit Forming

No

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Zedex-P Cold Syrup.
  • Know your triggers like allergens, such as pollen, dust, and food items that make your asthma and other respiratory diseases severe.
  • Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
  • Drink extra fluids while you take Zedex-P Cold Syrup to help loosen congestion and lubricate the throat.
  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Learning breathing exercises will help you move more air in and out of your lungs.

Special Advise

  • You are recommended to inform your doctor that you are taking Zedex-P Cold Syrup before undergoing any medical tests or surgery.
  • It is advised to stop using Zedex-P Cold Syrup if your cough persists for more than one week and consult your doctor.

Disease/Condition Glossary

Coughing:  Coughing occurs as a reflex action in the throat when there is mucus or other foreign irritant. Cough can be dry or productive. A productive cough (wet cough) develops sputum (phlegm or mucus) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing out thick, solid white mucus, it indicates that you may have a bacterial infection in the airways. Clear or light-coloured mucus indicates allergies or minor infections in the respiratory tract, and yellow or green mucus indicates a respiratory infection.

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Alcohol

Caution

It is not known whether it is safe to consume alcohol with Zedex-P Cold Syrup. Please consult your doctor before using Zedex-P Cold Syrup. However, it is better to avoid alcohol to prevent the incidence of side effects.

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Pregnancy

Caution

There are no adequate and well-controlled studies on pregnant women. Please inform your doctor if you are pregnant or planning for pregnancy; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor; there is no substantial research yet on using Zedex-P Cold Syrup in breastfeeding/nursing mothers. Your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Do not drive or operate machinery if you experience sleepiness, dizziness, increased/uneven heart rate and shakiness while using Zedex-P Cold Syrup. This may affect your ability to drive. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Zedex-P Cold Syrup should be used with caution in patients with liver diseases. Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Zedex-P Cold Syrup.

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Kidney

Caution

Zedex-P Cold Syrup should be used with caution in patients with kidney diseases. Let your doctor know if you have any history of kidney diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Zedex-P Cold Syrup.

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Children

Caution

Zedex-P Cold Syrup is not recommended for use in children less than four years of age. The dose may have to be adjusted by your doctor, depending on the condition of your child's symptoms and age.

Country of origin

India

Manufacturer/Marketer address

Wockhardt Towers, Bandra Kurla Complex, Bandra (East), Mumbai 400051, Maharashtra, India
Other Info - ZED0067

Author Details

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FAQs

Zedex-P Cold Syrup is used to treat cough.
Zedex-P Cold Syrup consists of four medicines, namely: Bromhexine (mucolytic), Dextromethorphan (cough suppressant), Phenylephrine (decongestant), Menthol (Coolant). Bromhexine makes sputum less viscous and makes it easier to cough out. Dextromethorphan relieves cough by reducing cough receptor activity, thereby affecting signals in the brain that trigger cough reflex. Phenylephrine helps in shrinking the blood vessels in the nostrils and the passage and reducing stuffy nose. Menthol produces a cooling sensation and relieves throat irritation.
Zedex-P Cold Syrup should preferably be used after taking your meal to decrease the occurrence of side effects. Please follow your doctor's advice on how you should use this medicine.
Inform your doctor before taking Zedex-P Cold Syrup, if you have any heart, liver, kidney diseases, depression and Parkinson's disease.
Yes, you may experience headaches and shakiness after using Zedex-P Cold Syrup. Drink plenty of water and take a rest to manage your headache. Shakiness goes away gradually. Consult your doctor if these symptoms persist longer.
Zedex-P Cold Syrup is not recommended for use if you have a stomach ulcer since mucolytics like Bromohexine may disrupt the gastric mucosal barrier, therefore cautiously administered in patients with a stomach ulcer.

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