Zapiz-0.5 mg Tablet belongs to the group of medications called benzodiazepines, primarily used to treat seizures or fits due to epilepsy, panic disorder and involuntary muscle spasms. Zapiz-0.5 mg Tablet may also be used to treat restless leg syndrome. Epilepsy is a common neurological disorder that produces recurrent seizures. Seizures occur due to a sudden burst of electrical activity in the brain that disrupts its normal functioning. Panic disorder is an anxiety disorder characterised by frequent episodes of panic or fear.

Zapiz-0.5 mg Tablet contains clonazepam, which works by increasing the level of a calming chemical known as gamma-aminobutyric acid (GABA) in the brain. This helps relieve anxiety and seizures (fits). It also helps relax the tense muscles. Thereby, Zapiz-0.5 mg Tablet aids in the treatment of seizures, panic disorder, and involuntary muscle spasms.

Your doctor will advise you on how often you need to take this medicine based on your medical condition. In some cases, Zapiz-0.5 mg Tablet may cause side effects such as drowsiness, dizziness, fatigue, and problems with memory, walking, and coordination. Most of these side effects do not require medical attention and gradually resolve over time. However, please contact your doctor if the side effects are persistent.

Zapiz-0.5 mg Tablet is a habit-forming drug. Therefore, before stopping this medicine, consult your doctor as it may cause withdrawal symptoms like seizures that do not stop, hallucinations (hearing or seeing things that are not there), shaking, and stomach and muscle cramps. If you are pregnant or breastfeeding, consult your doctor before taking Zapiz-0.5 mg Tablet . Avoid drinking alcohol while taking Zapiz-0.5 mg Tablet as it may cause increased dizziness and drowsiness. It is recommended not to drive or operate any machinery as Zapiz-0.5 mg Tablet may cause dizziness, drowsiness, and problems with walking and coordination.

Zapiz-0.5 mg Tablet belongs to the group of medications called benzodiazepines, primarily used to treat seizures or fits due to epilepsy, panic disorder and involuntary muscle spasms. Zapiz-0.5 mg Tablet may also be used to treat restless leg syndrome. Zapiz-0.5 mg Tablet contains clonazepam, which works by increasing the level of a calming chemical known as gamma-aminobutyric acid (GABA) in the brain. It decreases the feeling of nervousness, stress, and anxiety, which leads to a state of calmness and relaxation. Zapiz-0.5 mg Tablet benefits people who struggle with anxiety and worries in daily life. Regular intake of the prescribed dose of Zapiz-0.5 mg Tablet improves social life and the ability and performance at work, and general wellbeing.

• Drowsiness
• Dizziness
• Fatigue
• Problems with memory, walking, and coordination

Do not take Zapiz-0.5 mg Tablet if you are allergic to clonazepam or any benzodiazepine class of drugs (diazepam, chlordiazepoxide, bromazepam, or flurazepam). Inform your doctor if you have lung disease, glaucoma, muscle weakness (myasthenia gravis), sleep apnoea (difficulty in sleeping), depression, mood problems, suicidal behaviour/thoughts, liver or kidney problems. Taking Zapiz-0.5 mg Tablet with opioid medicines can cause severe drowsiness, breathing problems, coma, and death. Zapiz-0.5 mg Tablet should be taken with extreme caution in patients with a history of alcohol or drug abuse. Do not stop taking Zapiz-0.5 mg Tablet suddenly as it may cause withdrawal symptoms.

Drug-Drug Interactions: Zapiz-0.5 mg Tablet may interact with opioid analgesic medications (alfentanil, buprenorphine, codeine, hydrocodone, hydromorphone), antipsychotic medications (droperidol, olanzapine), anaesthesia medications (ketamine), antidepressant medications (sodium oxybate), medicines used to lower blood pressure (enalapril, amlodipine, felodipine, indapamide), acidity medicine (cimetidine), antibiotic medications (rifampicin, fluconazole) and anticonvulsants (diazepam, lorazepam).

Drug-Food Interactions: Limit or avoid the consumption of caffeine and alcohol.

Drug-Disease Interactions: Inform your doctor if you have acute alcohol intoxication, closed-angle glaucoma, drug dependence, respiratory depression, renal/liver disease, suicidal tendency, depression, obesity and paradoxical reactions.

• ALFENTANIL
• BUPRENORPHINE
• CODEINE
• HYDROMORPHONE
• DROPERIDOL
• OLANZAPINE
• KETAMINE
• SODIUM OXYBATE
• ENALAPRIL
• AMLODIPINE
• FELODIPINE
• INDAPAMIDE
• CIMETIDINE
• RIFAMPICIN
• FLUCONAZOLE
• DIAZEPAM
• LORAZEPAM

• Do regular exercise, which can help lower anxiety by releasing endorphins and improving your sleep and self-image.
• Find humor in your daily life. Try to watch light-hearted shows to help relieve stress.
• You can increase your mindfulness by including yoga, meditation, mindfulness-based cognitive therapy, and mindfulness-based stress reduction.
• Drink enough water to stay hydrated, and limit or avoid alcohol and caffeine to relieve anxiety.
• Include a diet rich in whole grains, vegetables, and fruits.
• Herbs like turmeric, ginger, and chamomile contain anti-inflammatory properties. Including this stuff in meals can reduce inflammation caused due to anxiety disorder.
• Reduce alcohol, caffeine, added sugar, high salt, and high fat intake. Especially trans-fat may also help reduce inflammation.
• You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea and lemon.
• Try to spend time with your friends and family. Having a strong social network may help you lower the risk of anxiety.

• Zapiz-0.5 mg Tablet can cause dependence and abuse. Therefore, take Zapiz-0.5 mg Tablet only in prescribed doses and as directed by your doctor. Do not self-medicate.
• Zapiz-0.5 mg Tablet may cause suicidal thoughts. Consult your doctor immediately if you notice suicidal behaviour.

Seizures: Fits/Seizure is a sudden rush of electrical activity in the brain. It is of two types: Generalized seizure (affects the entire brain) and Partial seizures (affects one part of the brain). A mild seizure might be difficult to recognize as it lasts for only a few seconds, during which one lacks awareness. Stronger seizures cause uncontrollable muscle twitches and spasms, lasting for a few seconds to several minutes. Lack of sleep, high fever, stress, bright lights, caffeine, certain medicines, alcohol, and skipping meals/overeating are a few of the most common triggers for seizures.

Panic disorder: Panic disorder is an anxiety disorder characterised by frequent episodes of panic or dread. At times, everyone feels sensations of anxiety and panic. It is a natural reaction to stressful or potentially harmful conditions. However, someone suffering from panic disorder experiences worries, stress, and panic on a regular basis and at any moment, frequently for no apparent cause.

Involuntary muscle spasm: When the nerve impulses that control muscle movements are damaged or interrupted, it could lead to muscle spasms. The sudden involuntary contractions of the muscle can be painful and uncomfortable. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty in movement, and pain in affected muscles and joints. Fatigue (weakness), stress, extreme heat or cold, infection and tight clothing can trigger muscle spasms.

Restless leg syndrome: Restless leg syndrome, also known as Willis-Ekbom illness, is a common nervous system disorder characterised by an intense, irresistible urge to move the legs. The primary symptom of restless leg syndrome is a strong need to move the legs. It can also induce a creeping or crawling sensation in the feet, calves, and thighs. The sensation is frequently exacerbated in the evening or at night. The arms are occasionally affected as well.