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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 30, 2024 | 5:52 AM IST

Xygrel 90 Tablet is taken to prevent heart attack or stroke in people at high risk of heart disease. It helps to prevent blood clots in people with acute coronary syndrome (heart doesn't receive enough oxygen) who have had stents placed in blood vessels in their heart. It contains Ticagrelor, which prevents blood clot formation in the blood vessels by making platelets less sticky. In some cases, you may experience dyspnea (shortness of breath), tightness in the chest, blurred vision, nosebleeds, dizziness, faintness, or lightheadedness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition

TICAGRELOR-90MG

Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Xygrel 90 Tablet

Xygrel 90 Tablet belongs to the antiplatelet drugs (blood thinners) primarily taken to prevent heart attack or stroke in people at high risk of heart disease. Xygrel 90 Tablet  helps to prevent blood clots in people with acute coronary syndrome (heart doesn't receive enough oxygen) who have had stents placed in blood vessels in their heart. A heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is often an accumulation of cholesterol, fat, and other substances, which form plaque in the arteries that feed the heart (coronary arteries). A heart attack signs include chest pain, upper body pain, sweating, nausea, fatigue, and trouble breathing.

Xygrel 90 Tablet contains Ticagrelor, which is a blood thinner that prevents clot formation in the blood vessels. Platelets are blood cells that stick together and block any cuts and breaks in blood vessels. But platelets can stick together inside already narrowed blood vessels to form a clot in people at risk of heart attack or stroke. The clot can stop blood from flowing to the heart or brain and cause a heart attack or stroke. Here, Xygrel 90 Tablet slows the blood's clotting action by making platelets less sticky.

Your doctor will advise you how often you take Xygrel 90 Tablet based on your medical condition. In some cases, you may experience dyspnea (shortness of breath), tightness in the chest, blurred vision, nosebleeds, dizziness, faintness, or lightheadedness. If side effects are persistent, talk to your doctor. Xygrel 90 Tablet may cause you to bleed more easily. You should not take Xygrel 90 Tablet if you have bleeding in your brain, a problem with blood flow, or any other bleeding risk factor.

Before taking the Xygrel 90 Tablet , let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. Xygrel 90 Tablet should not be stopped even if you feel better without consulting your doctor, as stopping a sudden intake of Xygrel 90 Tablet may worsen your condition and increase the risk of a future heart attack. The patient should inform the doctor that they are taking Xygrel 90 Tablet before any surgery is scheduled or any new medicine is taken. Don't take Xygrel 90 Tablet before or after having heart bypass surgery. Before using Xygrel 90 Tablet , consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Xygrel 90 Tablet

Prevention of Heart attack, Stroke, Acute Coronary Syndrome.

Medicinal Benefits

Xygrel 90 Tablet is an antiplatelet (blood thinner) and plays a vital role in preventing the formation of harmful blood clots in your blood vessels. Xygrel 90 Tablet work by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. Thus, it reduces the risk of heart attack, stroke, and acute coronary syndrome (heart doesn't receive enough oxygen or blood) in heart disease patients and patients who have undergone recent heart surgery with a stent.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Orodispersible tablet/mouth-dissolving tablet: Keep the tablet in the mouth and allow it to disintegrate. Do not swallow as a whole. Avoid handling the strip with wet hands.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Xygrel 90 Tablet

  • Dyspnea (shortness of breath)
  • Tightness in the chest
  • Blurred vision
  • Nosebleeds
  • Dizziness
  • Faintness or lightheadedness when getting up suddenly from a lying or sitting position
  • High level of uric acid in your blood
  • Severe pain and swelling in your joints – these are signs of gout
  • Bruising
  • Headache
  • Diarrhoea
  • Indigestion
  • Constipation
  • Bleeding after surgery or from cuts (for example, while shaving) and wounds more than is normal
  • Bleeding from your stomach lining (ulcer)
  • Bleeding gums

Drug Warnings

You should avoid taking Xygrel 90 Tablet if you are allergic to Xygrel 90 Tablet or any active and inactive ingredients present in it.  Let your doctor know if you have a medical condition that causes bleeding such as hemophilia, stomach ulcer, or bleeding in your head or bowel. Caution is required before giving Xygrel 90 Tablet to the kidney or liver problems patients. People affected with respiratory problems like asthma, nasal polyps, or rhinitis should consult a doctor before intake of Xygrel 90 Tablet . Xygrel 90 Tablet is not recommended for the breastfeeding mother as it passes into the breast milk. The safety and effectiveness in children less than 18 years of age have not been established, so Xygrel 90 Tablet should not be given to them.

Drug Interactions

Drug-Drug Interactions: Xygrel 90 Tablet interact with medicines to thin the blood or prevent blood clots (aspirin, warfarin), pain relievers (ibuprofen), antidepressants (citalopram, nefazodone), antibiotics (clarithromycin, rifampicin), to treat HIV infection and AIDS (ritonavir, atazanavir), anti-epileptic (phenytoin, carbamazepine), medicines used to lower cholesterol (simvastatin), medicine for heart problems(digoxin).

Drug-Food Interactions: Xygrel 90 Tablet interacts with grapefruit, drinking grapefruit juice while taking Xygrel 90 Tablet can increase the side effects of Xygrel 90 Tablet . Xygrel 90 Tablet may also interact with St John's wort plant (used for depression) and Ginkgo biloba and increase bleeding risk.

Drug-Disease Interactions: Xygrel 90 Tablet should not be given to people with stomach ulcers, haemophilia (a bleeding disorder), haemorrhage (bleeding in your brain), and kidney or liver problems.

Drug-Drug Interactions Checker List

  • WARFARIN
  • IBUPROFEN
  • CITALOPRAM
  • CLARITHROMYCIN
  • RIFAMPICIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • SIMVASTATIN
  • DIGOXIN
  • ASPIRIN
  • NEFAZODONE
  • RITONAVIR
  • ATAZANAVIR

Habit Forming

No

Diet & Lifestyle Advise

  • Reducing weight and having a healthy BMI is very important in enhancing cardiac health.

  • 30 minutes of daily physical exercise can go a long way in preventing heart disease.

  • Avoid smoking to improve cardiac health.

  • Invest in a healthy, balanced diet. Avoid fatty foods, keep your cholesterol in check and load up on the green leafy vegetables, fish, lean meats, nuts and dry fruits. 

  • Reducing stress is very important in keeping a healthy heart. Try yoga and meditation for a relaxed state of mind.

Special Advise

  • Take Xygrel 90 Tablet exactly as prescribed. 

  • Talk to your physician if you miss a dose of Xygrel 90 Tablet . Never take a double dose. 

  • Do not discontinue taking Xygrel 90 Tablet abruptly or without the physician's advice.

  • Please know that your doctor may order blood tests to check your hormone levels while you are on Xygrel 90 Tablet . 

  • Your doctor may order a D-dimer to check your clotting profile while on Xygrel 90 Tablet .

  • Your doctor may order liver function tests (LFT’s) and a complete blood picture (CBP) to ascertain the effects of Xygrel 90 Tablet .

Disease/Condition Glossary

Blood clot: Blood clot is an aggregation of blood that changes from a liquid to a gel-like state. Clotting is a natural process that prevents you from losing too much blood in surgery or cut, accident, and trauma. When a clot forms inside the veins, it won't always dissolve independently and can become an even life-threatening situation.

Heart attack: Heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is often an accumulation of fat, cholesterol, and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). During a heart attack (myocardial infarction), the blood supply which nourishes the heart with oxygen is cut off. This causes the heart muscle to die. A heart attack signs include chest pain, upper body pain, sweating, nausea, fatigue, and trouble breathing.

Stroke: When our brain does not get sufficient oxygen and blood supply, it starts dying within a few minutes leading to a heart attack or stroke.

Acute coronary syndrome: Acute coronary syndrome is most often caused by plaque rupture or clot formation in the heart's arteries. The symptoms may include heart attack-like chest pressure, chest pressure while resting or doing light activity, or sudden heart stoppage.

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Alcohol

Unsafe

It is unsafe to consume alcohol since it may worsen the side effects like dizziness and increases blood pressure.

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Pregnancy

Caution

Please consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Xygrel 90 Tablet may pass into breast milk and may cause side effects in a breastfed child. Please consult your doctor before starting Xygrel 90 Tablet .

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using Xygrel 90 Tablet .

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Liver

Caution

Let your doctor know if you had or have any history of liver disease or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Xygrel 90 Tablet . However, Xygrel 90 Tablet is not recommended in patients with severe liver problems.

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Kidney

Caution

Let your doctor know if you had or have any history of kidney diseases/conditions. Your doctor will weigh the benefits and potential risks before prescribing Xygrel 90 Tablet . However, Xygrel 90 Tablet is not recommended in patients with severe kidney problems.

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Children

Caution

Xygrel 90 Tablet is not recommended for children below the age of 18 years. The safety and effectiveness of Xygrel 90 Tablet have not been established in children.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - XYG0001

Author Details

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FAQs

Xygrel 90 Tablet is primarily used to prevent heart attack or stroke in people at high risk of heart disease. It helps to prevent blood clots in people with acute coronary syndrome (the heart doesn't receive enough oxygen) who have had stents placed in blood vessels in their heart.
If the Xygrel 90 Tablet is taken every day, the Xygrel 90 Tablet stops platelets from clumping together to form unwanted blood clots and prevents heart attacks and strokes.
Yes, taking Xygrel 90 Tablet can increase the risk of bleeding. So, please be very cautious while cutting fingernails or toenails, shaving, or using sharp objects to avoid bleeding.
Please consult your doctor if Xygrel 90 Tablet needs to be stopped before undergoing surgery. The doctor might ask you to stop taking Xygrel 90 Tablet a few days before surgery since it can cause an increased risk of bleeding during surgery.
There might be a problem if you take herbal therapies with Xygrel 90 Tablet , especially those that affect blood like Ginkgo Biloba, Grapefruits, St John's wort plant extract used as an antidepressant. Taking together can increase your risk of bleeding. Tell your doctor if you are using any herbal supplements before taking Xygrel 90 Tablet .
No, Xygrel 90 Tablet may make it harder to breathe. Consult your doctor if the problem persists, he/she may adjust the dose or prescribe an alternative medicine.
Do not drink grapefruit juice while taking Xygrel 90 Tablet . Grapefruit juice may increase the blood-thinning effect of the medicine.
Xygrel 90 Tablet contains ticagrelor, which when taken with clopidogrel may increase the risk of bleeding. Consult the doctor before taking other medicines with Xygrel 90 Tablet .
Xygrel 90 Tablet should not be discontinued without a doctor's consultation. Stopping Xygrel 90 Tablet might increase the risk of a heart attack or stroke.
Xygrel 90 Tablet may cause blood in urine. Consult the doctor if you experience this.
Xygrel 90 Tablet might lower the blood pressure. Let the doctor know if you are taking anti-hypertensives (blood pressure-lowering medicines). Regular monitoring of blood pressure levels is advised.
Xygrel 90 Tablet can be taken with other medicines if prescribed by the doctor. Before starting Xygrel 90 Tablet inform the doctor if you are taking any other medicines to prevent interactions.
Xygrel 90 Tablet is an antiplatelet medicine which inhibits the aggregation of platelets that may cause a heart attack or stroke.
Limit alcohol consumption with Xygrel 90 Tablet as it might increase the risk of bleeding.
Xygrel 90 Tablet may cause significant, sometimes fatal bleeding. Inform the doctor if you have/had a condition that causes you to bleed more easily than normal; bleeding in your stomach, intestines, or brain; stomach ulcer; polyps (abnormal growths in the lining of the large intestine); a stroke or mini-stroke; or liver disease. Seek immediate medical attention if you experience unexplained, severe, long-lasting, or uncontrollable bleeding; red or black, tarry stools; pink or brown urine; vomit that is bloody or that looks like coffee grounds; or coughing up blood or blood clots.
Xygrel 90 Tablet works within 30 minutes of taking the first dose.

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