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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:37 PM IST
Xultophy 3ml Pre-Filled Pen is used to treat type-2 diabetes mellitus adjunct to diet and exercise. It contains Liraglutide and Insulin degludec which helps control blood glucose and insulin levels by facilitating the reuptake of glucose in the fat and muscle cells. It helps control blood sugar levels in people with diabetes thereby preventing serious complications of diabetes like kidney damage and blindness.
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Prescription drug

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Manufacturer/Marketer

Novo Nordisk India Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Xultophy 3ml Pre-Filled Pen

Xultophy 3ml Pre-Filled Pen belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus adjunct to diet and exercise. Type-2 diabetes mellitus is also known as non-insulin-dependent diabetes or adult-onset diabetes. It is a medical condition in which blood glucose levels are above normal due to insulin deficiency, insulin resistance, or both.
 
Xultophy 3ml Pre-Filled Pen is a combination of two drugs, namely: Liraglutide and Insulin degludec. Liraglutide lowers the amount of sugar made by the body and helps the body make more insulin during meals. Insulin degludec works in a similar manner as the insulin produced by the body. It lowers blood glucose levels and facilitates the reuptake of glucose in the fat and muscle cells. Together, Xultophy 3ml Pre-Filled Pen helps in controlling the blood glucose levels.
 
You are advised to use Xultophy 3ml Pre-Filled Pen for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as hypoglycaemia (low blood glucose levels), injection site reactions, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are recommended to consult your doctor if the side effects persist or worsen.
 
Do not skip any doses or stop taking Xultophy 3ml Pre-Filled Pen suddenly without consulting your doctor, as it may lead to increased blood glucose levels. Consult your doctor if you are pregnant or breastfeeding. Xultophy 3ml Pre-Filled Pen is not recommended for children below 18 years. Avoid alcohol consumption as it might affect blood sugar levels. Xultophy 3ml Pre-Filled Pen may cause hypoglycaemia, so drive only if you are alert. Inform your doctor about all the medications you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of Xultophy 3ml Pre-Filled Pen

Treatment of Type-2 diabetes mellitus

Medicinal Benefits

Xultophy 3ml Pre-Filled Pen is a combination of two anti-diabetic drugs, namely: Liraglutide and Insulin degludec. Xultophy 3ml Pre-Filled Pen is used to treat type-2 diabetes mellitus adjunct to diet and exercise. Liraglutide lowers the amount of sugar made by the body and helps the body make more insulin during meals. Insulin degludec works similarly as the insulin produced by the body. It lowers blood glucose levels and facilitates the reuptake of glucose in the fat and muscle cells. Together, Xultophy 3ml Pre-Filled Pen helps in controlling blood glucose levels.

Directions for Use

Xultophy 3ml Pre-Filled Pen should be administered sub-cutaneous only. Wash your hands properly and adjust the dose as advised by the doctor. Clean the injection site and inject the dose subcutaneously in the abdomen/thighs/upper arm. Safely discard the needle.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Xultophy 3ml Pre-Filled Pen

  • Hypoglycaemia (low blood glucose levels)
  • Injection site reactions
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation

Drug Warnings

Do not use Xultophy 3ml Pre-Filled Pen if you are allergic to any of its contents. Inform your doctor if you have type 1 diabetes, diabetic ketoacidosis, inflammatory bowel disease, delayed gastric emptying, eye problems, thyroid problems, kidney/liver problems or if you are taking any oral anti-diabetic medicines. Consult your doctor if you are pregnant or breastfeeding. Xultophy 3ml Pre-Filled Pen is not recommended for children below 18 years. Xultophy 3ml Pre-Filled Pen may cause hypoglycaemia, so drive only if you are alert. Do not use Xultophy 3ml Pre-Filled Pen if the pen is damaged, if the solution is not clear or if the pen has not been stored properly. 

Drug Interactions

Drug-Drug Interactions: Xultophy 3ml Pre-Filled Pen may interact with a blood thinner (warfarin), anti-diabetic (pioglitazone), octapeptide (octreotide), somatostatin agonist (lanreotide), sympathomimetic (epinephrine), anti-asthma (salbutamol, terbutaline), androgenic hormones (danazol), anabolic steroids (testosterone), pain killer (aspirin), thiazide diuretics, oral contraceptives, thyroid hormones, growth hormones, beta-blockers, monoamine oxidase inhibitors, sulphonamides, and angiotensin-converting enzyme inhibitors.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have type 1 diabetes, diabetic ketoacidosis, inflammatory bowel disease, delayed gastric emptying, eye problems, or thyroid problems.

Drug-Drug Interactions Checker List

  • WARFARIN
  • PIOGLITAZONE
  • OCTREOTIDE
  • EPINEPHRINE
  • SALBUTAMOL
  • TERBUTALINE
  • DANAZOL
  • TESTOSTERONE
  • ASPIRIN

Habit Forming

No

Diet & Lifestyle Advise

  • Include foods rich in healthy carbohydrates and fibre, fruits, whole grains, and vegetables in your diet.
  • Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
  • Follow a healthy diet and walk for at least 45 minutes to complement treatment with Xultophy 3ml Pre-Filled Pen.
  • Maintain a healthy weight by exercising regularly.
  • Rest properly, avoid stress by doing meditation or yoga.

Special Advise

  • Regularly monitor blood glucose levels while taking Xultophy 3ml Pre-Filled Pen.
  • Try not to skip any doses and take Xultophy 3ml Pre-Filled Pen for as long as your doctor has prescribed it for you.
  • To avoid contamination, always use a new needle for each injection.
  • Rotate the injection site to prevent changes to the fatty tissue under the skin like skin thickening, skin lumps or shrinking under the skin.

Disease/Condition Glossary

Type-2 diabetes mellitus: It is also known as non-insulin-dependent diabetes. It is a chronic or lifelong disease that keeps the body from utilizing insulin properly. Diabetes is a medical condition in which blood glucose levels are above normal. People with type 2 diabetes either do not produce enough insulin, or the insulin produced cannot perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes; hence, it is also known as adult-onset diabetes. Type 2 diabetes symptoms include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while using Xultophy 3ml Pre-Filled Pen as alcohol might affect blood sugar levels.

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Pregnancy

Caution

Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will prescribe only if the benefits outweigh the risks.

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Driving

Caution

Xultophy 3ml Pre-Filled Pen may cause hypoglycaemia. So, drive, and operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Xultophy 3ml Pre-Filled Pen is not recommended for children below 18 years as the effectiveness has not been established.

Country of origin

India

Manufacturer/Marketer address

Plot No.32, 47-50, EPIP Area, Whitefield, Bangalore - 560 066
Other Info - XUL0003

Author Details

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FAQs

Xultophy 3ml Pre-Filled Pen is used to treat type-2 diabetes mellitus adjunct to diet and exercise.
Xultophy 3ml Pre-Filled Pen contains Liraglutide and Insulin degludec. Liraglutide lowers the amount of sugar made by the body and helps the body make more insulin during meals. Insulin degludec works similarly to the insulin produced by the body. It lowers blood glucose levels and facilitates the reuptake of glucose in the fat and muscle cells. Together, Xultophy 3ml Pre-Filled Pen helps in controlling blood glucose levels.
Xultophy 3ml Pre-Filled Pen may sometimes lower the blood glucose levels more than normal, leading to hypoglycaemia. Regularly monitor your blood sugar levels while taking Xultophy 3ml Pre-Filled Pen. Always carry any sugary food and consume it if you experience hypoglycaemia symptoms such as headache, drowsiness, cold sweat, feeling sick, unusual tiredness or weakness, and visual disturbances.
Hypoglycaemia may occur following prolonged or severe exercise, during illness, alcohol consumption, low food intake, or when Xultophy 3ml Pre-Filled Pen is taken along with other antidiabetic medicines.
Maintain a healthy diet by regular intake of carbohydrates such as bread and products containing starch and sugar. Eat your meals regularly, and do not exercise heavily for longer durations with an empty stomach.
Do not stop using Xultophy 3ml Pre-Filled Pen without consulting your doctor as it may cause an increase in blood glucose levels. Continue taking Xultophy 3ml Pre-Filled Pen for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while using Xultophy 3ml Pre-Filled Pen.
Before opening, store Xultophy 3ml Pre-Filled Pen in a refrigerator at 2°C to 8°C. Do not freeze. During use, you can keep Xultophy 3ml Pre-Filled Pen at room temperature (below 30°C) or in a refrigerator (2°C to 8°C) for up to 21 days. The product should be thrown away 21 days after the first opening. Always keep the cap of the pre-filled syringe on to protect it from the light.

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Keep Refrigerated. Do not freeze.Prepaid payment required.

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