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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:26 PM IST
Wisperzyme 180 mg/96 mg/200 mg Tablet DT is used to relieve musculoskeletal pain in the conditions of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It prevents cell damage, reduces toxins, protects the body from damage caused by free radicals (toxins), and decreases swelling. Also, it removes dead skin cells and allows the growth of healthy tissue. In some cases, it may cause side effects such as experience vomiting, nausea, diarrhea, rash, or mouth sores. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Wisperzyme 180 mg/96 mg/200 mg Tablet DT

Wisperzyme 180 mg/96 mg/200 mg Tablet DT is used to relieve musculoskeletal pain in the conditions of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time (acute) or long time (chronic).  

Wisperzyme 180 mg/96 mg/200 mg Tablet DT is a combination of one antioxidant (Rutoside) and two enzymes (Trypsin and Bromelain). Rutoside is an antioxidant that prevents cell damage, reduces toxins, protects the body from damage caused by free radicals (toxins), and decreases swelling. Trypsin removes dead skin cells and allows the growth of healthy tissue. On the other hand, Bromelain is a pineapple extract that limits fibrin formation by reducing clots or plaque at the damaged/injured site. Together it reduces swelling and inflammation by producing substances in the body against pain and swelling. Thus, Wisperzyme 180 mg/96 mg/200 mg Tablet DT helps in relieving edema (fluid overload) and inflammation and promotes wound healing. 

Take Wisperzyme 180 mg/96 mg/200 mg Tablet DT with or without food as prescribed by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you how often you take your tablets based on your medical condition. In some cases, you may experience vomiting, nausea, diarrhea, rash, or mouth sores. Most of these side effects of Wisperzyme 180 mg/96 mg/200 mg Tablet DT do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Wisperzyme 180 mg/96 mg/200 mg Tablet DT or any other medicines, please tell your doctor. Avoid Wisperzyme 180 mg/96 mg/200 mg Tablet DT in patients who are allergic to pineapple, carrot, papaya, fennel, and pollens. Wisperzyme 180 mg/96 mg/200 mg Tablet DT is not recommended for pregnant women as it contains Bromelain, which may cause abortion or miscarriage. If you are pregnant or planning for pregnancy, please consult a doctor before taking Wisperzyme 180 mg/96 mg/200 mg Tablet DT. Before undergoing any planned surgery, inform your doctor that you are taking Wisperzyme 180 mg/96 mg/200 mg Tablet DT. It should be stopped a minimum of 2 weeks before surgery due to increased bleeding risk during and after surgery. If you have blood pressure problems, clotting or bleeding problems, infection, hematuria (blood in urine), hematemesis (vomiting blood), or kidney or liver disorders, inform your doctor before taking Wisperzyme 180 mg/96 mg/200 mg Tablet DT.

Uses of Wisperzyme 180 mg/96 mg/200 mg Tablet DT

Treatment of Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis.

Medicinal Benefits

Wisperzyme 180 mg/96 mg/200 mg Tablet DT is a combination of one antioxidant (Rutoside) and two enzymes (Trypsin, Bromelain). Rutoside is an antioxidant (substances that prevent damage to cells) that works by protecting the body from damage caused by free radicals (unstable molecules produced by the body) and further decreases swelling. Trypsin removes dead skin cells and allows the growth of healthy tissue. In combination with Bromelain, Trypsin reduces swelling and inflammation by producing substances in the body against pain and swelling in the conditions of joint disorders like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.  

Directions for Use

Take Wisperzyme 180 mg/96 mg/200 mg Tablet DT with or without food as prescribed by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Wisperzyme 180 mg/96 mg/200 mg Tablet DT

  • Vomiting

  • Nausea

  • Diarrhea

  • Rash

  • Mouth sores

  • Gastrointestinal discomfort

Drug Warnings

If you are allergic to Wisperzyme 180 mg/96 mg/200 mg Tablet DT or any other medicines, please tell your doctor. People allergic to pineapple, carrot, papain, fennel, and pollen should avoid the intake of Wisperzyme 180 mg/96 mg/200 mg Tablet DT. It is not recommended for pregnant women as it contains Bromelain, which may cause miscarriage, so if you are pregnant or planning for pregnancy, let your doctor know about this. If you are about to undergo any surgery, inform your doctor that you are taking Wisperzyme 180 mg/96 mg/200 mg Tablet DT. It should be stopped a minimum of 2 weeks before surgery as Wisperzyme 180 mg/96 mg/200 mg Tablet DT may increase the risk of bleeding during and after surgery. If you have blood pressure problems, clotting or bleeding problems, infection, hematuria (blood in urine), hematemesis (vomiting blood), kidney or liver disorders, inform your doctor before taking Wisperzyme 180 mg/96 mg/200 mg Tablet DT.

Drug Interactions

Drug-Drug Interaction: Wisperzyme 180 mg/96 mg/200 mg Tablet DT may have interaction with painkillers (aspirin, diclofenac, ibuprofen, naproxen), blood thinners (warfarin, clopidogrel, dalteparin, enoxaparin, heparin), antibiotics (amoxicillin, demeclocycline, minocycline, tetracycline), drugs used to dissolve blood clots (alteplase, reteplase, streptokinase), high blood pressure-lowering medicines (captopril, enalapril, fosinopril, lisinopril).

Drug-Food Interaction: Wisperzyme 180 mg/96 mg/200 mg Tablet DT may interact with ginger, garlic, asafoetida, alfalfa, arnica, fenugreek, potato, soybean, licorice, red clover, celery, angelica, meadowsweet, quassia, willow,  chestnut, chamomile, and clover.

Drug-Disease Interaction: If you have blood pressure problems, clotting or bleeding problems, infection, hematuria (blood in urine), hematemesis (vomiting blood), kidney or liver disorders, inform your doctor before taking Wisperzyme 180 mg/96 mg/200 mg Tablet DT.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • DICLOFENAC
  • IBUPROFEN
  • NAPROXEN
  • WARFARIN
  • CLOPIDOGREL
  • DALTEPARIN
  • ENOXAPARIN
  • HEPARIN
  • AMOXICILLIN
  • DEMECLOCYCLINE
  • MINOCYCLINE
  • TETRACYCLINE
  • ALTEPLASE
  • RETEPLASE
  • STREPTOKINASE
  • CAPTOPRIL
  • ENALAPRIL
  • FOSINOPRIL
  • LISINOPRIL

Habit Forming

No

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, Vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercise like walking on a treadmill, bike riding, and swimming. You can also increase your muscle strength by lifting light weights.

  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

  • In the chronic condition of arthritis or joint pain, including fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize the level of chemicals called cytokines, which may increase inflammation.

  • Your sitting posture is important, especially when have pain and inflammation condition. Try to sit little as possible, and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your hips and knees at a right angle. Besides this, you can use a footrest if required.

Special Advise

Wisperzyme 180 mg/96 mg/200 mg Tablet DT must not be used by patients with severe inborn bleeding disorders like hemophilia, severe liver damage, and dialyzed patients. 

Disease/Condition Glossary

Osteoarthritis and rheumatoid arthritis: It is a chronic condition caused by wear and tear on the joints with sore/stiff joints, and pain worsens after activity or the end of the day. In rheumatoid arthritis, the immune system attacks musculoskeletal joints and other body parts with pain, fatigue, and swollen, warm, and inflamed-looking joints. Arthritis cannot be cured but can be managed. 

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Alcohol

Caution

The interaction of alcohol with Wisperzyme 180 mg/96 mg/200 mg Tablet DT is unknown. Please consult a doctor before consuming alcohol with Wisperzyme 180 mg/96 mg/200 mg Tablet DT.

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Pregnancy

Unsafe

Wisperzyme 180 mg/96 mg/200 mg Tablet DT is usually not recommended for pregnant women as it may cause miscarriage. However, please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

It is unknown whether Wisperzyme 180 mg/96 mg/200 mg Tablet DT is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding. Wisperzyme 180 mg/96 mg/200 mg Tablet DT is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Caution

Avoid driving if you experience any symptoms which may affect your ability to react or concentrate after taking Wisperzyme 180 mg/96 mg/200 mg Tablet DT.

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Liver

Caution

Take Wisperzyme 180 mg/96 mg/200 mg Tablet DT with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Wisperzyme 180 mg/96 mg/200 mg Tablet DT with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Wisperzyme 180 mg/96 mg/200 mg Tablet DT is not recommended for children until and unless prescribed by a doctor.

Country of origin

India
Other Info - WI79779

Author Details

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FAQs

Wisperzyme 180 mg/96 mg/200 mg Tablet DT is used to relieve musculoskeletal pain in the conditions of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
Wisperzyme 180 mg/96 mg/200 mg Tablet DT is a combination of one antioxidant (Rutoside) and two enzymes (Trypsin, Bromelain). Rutoside is an antioxidant (substances that prevent damage to cells) that works by protecting the body from damage caused by free radicals (unstable molecules produced by the body) and further decreases swelling. Trypsin removes dead skin cells and allows the growth of healthy tissue. Trypsin in combination with Bromelain reduces swelling and inflammation by producing substances in the body against pain and swelling.
Yes, Wisperzyme 180 mg/96 mg/200 mg Tablet DT may be used to treat menstrual cramps. Wisperzyme 180 mg/96 mg/200 mg Tablet DT is a pain killer that produces substances in the body against pain and swelling.
You are not recommended to take Wisperzyme 180 mg/96 mg/200 mg Tablet DT with warfarin as co-administration of these two medicines may slow down blood clotting and increase the risk of bleeding more easily. However, please consult a doctor before using Wisperzyme 180 mg/96 mg/200 mg Tablet DT with other medicines.
You may have to stop taking Wisperzyme 180 mg/96 mg/200 mg Tablet DT minimum 2 weeks before surgery as Wisperzyme 180 mg/96 mg/200 mg Tablet DT may increase the risk of bleeding during and after surgery. However, if you are about to undergo any surgery, inform your doctor that you are taking Wisperzyme 180 mg/96 mg/200 mg Tablet DT.
Arthritis is a non-curable disease but can be managed. Wisperzyme 180 mg/96 mg/200 mg Tablet DT does not cure arthritis but can relieve symptoms of arthritis-like joint pain and swelling.
No, trypsin is not a hormone. Wisperzyme 180 mg/96 mg/200 mg Tablet DT is a combination of two enzymes and one antioxidant.
Store Wisperzyme 180 mg/96 mg/200 mg Tablet DT in a cool and dry place as advised on the label. Protect from light. Keep it out of reach of children.
Wisperzyme 180 mg/96 mg/200 mg Tablet DT causes side effects such as nausea, vomiting, diarrhoea, rash, mouth sores, and gastro-intestinal discomfort. However, please contact a doctor if these side effects persist longer.

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