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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Nov 23, 2024 | 4:29 PM IST

Wikoryl 325 mg DT Tablet is a respiratory medicine mainly used to treat the common cold and allergies. This combination medicine works by blocking the action of histamine and thereby helps reduce symptoms like sneezing, watery eyes, or itchy/watery nose and throat. It may cause common side effects like drowsiness, sleepiness, nausea, fatigue, difficulty sleeping, and headache.

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Manufacturer/Marketer

Alembic Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Wikoryl 325 mg DT Tablet

Wikoryl 325 mg DT Tablet belongs to the class of medication called 'cough and cold medications' primarily used to treat common cold symptoms and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes. The common cold is a respiratory illness affecting the nose and throat. It is mostly caused by viruses known as 'rhinovirus'. The virus enters the body through the nose, mouth, or eyes and spreads quickly through droplets in the air when the person who is sick sneezes, coughs, or talks.

Wikoryl 325 mg DT Tablet is a combination of three drugs: Paracetamol (mild analgesic and antipyretic), Phenylephrine hydrochloride (decongestant), and Chlorpheniramine maleate (antihistamine/antiallergic). Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, which are responsible for pain and fever. Phenylephrine hydrochloride works by shrinking the blood vessels in the nasal passage. Thereby providing relief from congestion and decreasing excess mucus production. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy.

Take Wikoryl 325 mg DT Tablet as prescribed. Your doctor will recommend how often you must take Wikoryl 325 mg DT Tablet based on your medical condition. Some people may experience drowsiness, nervousness, headache, dizziness, insomnia (difficulty falling or staying asleep), blurred vision, constipation, and dry mouth. Most of these side effects of Wikoryl 325 mg DT Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Wikoryl 325 mg DT Tablet or any other medicines. If you are pregnant, it is advised to inform your doctor before using Wikoryl 325 mg DT Tablet . Do not use Wikoryl 325 mg DT Tablet if you are breastfeeding without a doctor’s advice, as it may be excreted in breast milk and cause harm to the baby. Wikoryl 325 mg DT Tablet is not recommended for children below four years. Please do not take more than the prescribed dose of Wikoryl 325 mg DT Tablet as it may cause liver damage.

Uses of Wikoryl 325 mg DT Tablet

Treatment of Common cold and Allergies

Medicinal Benefits

Wikoryl 325 mg DT Tablet contains Paracetamol, Phenylephrine hydrochloride, and Chlorpheniramine maleate. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine hydrochloride is a decongestant that works by contracting and narrowing the blood vessels. Thereby, providing relief from congestion and decreasing mucus production. Chlorpheniramine maleate is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.

Directions for Use

Take it with or without food as advised by the doctor. Swallow it whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Wikoryl 325 mg DT Tablet

  • Drowsiness
  • Nervousness
  • Headache
  • Dizziness
  • Insomnia (difficulty in falling or staying asleep)
  • Blurred vision
  • Constipation
  • Dry mouth

Drug Warnings

If you are allergic to Wikoryl 325 mg DT Tablet or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using Wikoryl 325 mg DT Tablet . Do not use Wikoryl 325 mg DT Tablet if you are breastfeeding without a doctor’s advice, as it may be excreted in breast milk and cause harm to the baby. Wikoryl 325 mg DT Tablet is not recommended for children below 4 years. Please do not take more than the prescribed dose of Wikoryl 325 mg DT Tablet as it may cause liver damage.  If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in the stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Wikoryl 325 mg DT Tablet .

Drug Interactions

Drug-Drug Interaction: Wikoryl 325 mg DT Tablet may interact with anti-allergic drugs (diphenhydramine, cetirizine), antidepressants (duloxetine, escitalopram), anticonvulsants (clonazepam), antianxiety drugs (alprazolam), muscle relaxants (cyclobenzaprine), cough suppressants (dextromethorphan), bronchodilator (albuterol), sleeping agent (ramelteon), pain and fever medicines (paracetamol), pain killers (ibuprofen).

Drug-Food Interaction: Avoid intake of Wikoryl 325 mg DT Tablet with chocolate and caffeine-containing foods such as cocoa beans and tea leaves as they may increase the risk of severity of side effects. Avoid consumption of alcohol with Wikoryl 325 mg DT Tablet  as it may increase the risk of liver damage and cause increased drowsiness, dizziness and difficulty in concentrating.

Drug-Disease Interaction: If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in the stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking Wikoryl 325 mg DT Tablet .

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE
  • CETIRIZINE
  • DULOXETINE
  • ESCITALOPRAM
  • CLONAZEPAM
  • ALPRAZOLAM
  • CYCLOBENZAPRINE
  • DEXTROMETHORPHAN
  • ALBUTEROL
  • PARACETAMOL
  • IBUPROFEN
  • RAMELTEON

Habit Forming

No

Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.
  • Eat plenty of foods rich in good bacteria, like yoghurt, to improve overall health.
  • Drink plenty of fluids to avoid dehydration.
  • Gargle with salt water for relief from sore throat.
  • Avoid consumption of alcohol with Wikoryl 325 mg DT Tablet as it may cause tiredness, drowsiness, or lack of concentration.

Special Advise

  • Do not give Wikoryl 325 mg DT Tablet to children below four years of age.
  • Do not take Wikoryl 325 mg DT Tablet for longer than seven days in a row (for adults) and five days (for children over 4).
  • If you have allergic skin reactions, such as skin redness or a rash that spreads and causes blistering and peeling, immediately contact a doctor.

Disease/Condition Glossary

Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’, affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected by having 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The symptoms of the common cold include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, and stuffy or runny nose. In some cases, the discharge from the nose may become thicker and yellow or green, which is not an indication of bacterial infection.

Allergies: It occurs when allergy-causing agents (allergens) attack and invade our body, thereby causing the release of histamines. This chemical messenger, 'histamine', causes swelling, inflammation, redness, itchiness, itchy/watery nose, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet dander, dust, pollen hairs, seasonal allergies like hay fever, etc.

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Alcohol

Unsafe

Avoid consumption of alcohol with Wikoryl 325 mg DT Tablet as it may increase the risk of liver damage and cause increased drowsiness, dizziness or difficulty in concentrating. Please consult a doctor before consuming alcohol with Wikoryl 325 mg DT Tablet .

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Pregnancy

Caution

The safety of Wikoryl 325 mg DT Tablet in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Wikoryl 325 mg DT Tablet may be excreted in breast milk and harm the baby. It may also slow milk production, so it is better to contact a doctor before a lactating mother takes it.

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Driving

Caution

Wikoryl 325 mg DT Tablet may cause blurred vision or impair thinking in some people. Therefore, drive only if you are alert after taking Wikoryl 325 mg DT Tablet .

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Liver

Caution

Take Wikoryl 325 mg DT Tablet with caution, especially if you have a history of Liver diseases/conditions. Your doctor may adjust the dose as required.

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Kidney

Caution

Take Wikoryl 325 mg DT Tablet with caution, especially if you have a history of Kidney diseases or conditions. Your doctor may adjust the dose as needed.

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Children

Caution

Wikoryl 325 mg DT Tablet is not recommended for children below four years of age. However, please consult a doctor before giving Wikoryl 325 mg DT Tablet to children.

Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,INDIA
Other Info - WIK0014

Author Details

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FAQs

Wikoryl 325 mg DT Tablet is used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes.
Wikoryl 325 mg DT Tablet contains Paracetamol, Phenylephrine hydrochloride, and Chlorpheniramine maleate. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Phenylephrine hydrochloride works by contracting and narrowing the blood vessels. Thereby providing relief from congestion and decreasing mucus production. Chlorpheniramine maleate works by blocking the action of histamine, a substance responsible for causing allergic reactions.
Wikoryl 325 mg DT Tablet contains paracetamol, which acts as a mild pain killer (analgesic) and fever reducer (antipyretic). It works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins, which are responsible for pain and fever.
Wikoryl 325 mg DT Tablet may cause drowsiness. It is not necessary for everyone taking Wikoryl 325 mg DT Tablet to experience this side effect. Therefore, avoid driving or operating heavy machinery if you feel drowsy after taking Wikoryl 325 mg DT Tablet .
It is not recommended to take Wikoryl 325 mg DT Tablet with Cetirizine, as co-administration of these two medicines may increase sedation and can cause drowsiness, dizziness, and difficulty concentrating. However, please consult a doctor before taking Wikoryl 325 mg DT Tablet with other medicines.
You are not recommended to stop taking Wikoryl 325 mg DT Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Wikoryl 325 mg DT Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Wikoryl 325 mg DT Tablet , please consult your doctor.
Do not use Wikoryl 325 mg DT Tablet if you have used an MAO inhibitor in the past 14 days, like isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine. Tell your doctor before taking Wikoryl 325 mg DT Tablet if you have nausea, stomach pain, itchy skin, loss of appetite, dark urine, clay-coloured stools, or jaundice (yellowing of your skin or eyes). In rare cases, paracetamol present in Wikoryl 325 mg DT Tablet may cause a severe skin allergic reaction. So, if you observe any skin blisters or redness or rash, stop taking Wikoryl 325 mg DT Tablet and contact your doctor.
No, Wikoryl 325 mg DT Tablet contains a decongestant ingredient called Phenylephrine hydrochloride, which may raise blood pressure, especially in people who already have high blood pressure (hypertension). If your blood pressure stays high after taking Wikoryl 325 mg DT Tablet , please consult your doctor.
You should take Wikoryl 325 mg DT Tablet at the recommended dose and duration or as prescribed by your doctor.
No, Wikoryl 325 mg DT Tablet may be excreted in breast milk and could harm the baby. It may also reduce milk production. Therefore, it is best to consult a doctor before a lactating mother takes it.
Yes, Wikoryl 325 mg DT Tablet contains a decongestant and an antihistamine, which can help relieve the symptoms of a blocked nose. The decongestant works to reduce nasal congestion, and the antihistamine helps with any allergy symptoms you may have. However, please consult your doctor before using Wikoryl 325 mg DT Tablet to ensure it is right for you.
No, do not take Wikoryl 325 mg DT Tablet for more than seven days in a row (for adults) or five days (for children over 4) without consulting your doctor. Using Wikoryl 325 mg DT Tablet for a longer time may cause side effects.
Wikoryl 325 mg DT Tablet is a medication commonly used to relieve symptoms of a cough and cold. However, it does not directly target the cough itself. It may help with some associated symptoms, such as sneezing, runny or stuffy nose, fever, headache, body pains, congestion, or watery eyes. Please consult your doctor for the medications effective for managing a cough.
Wikoryl 325 mg DT Tablet is composed of Chlorpheniramine maleate, Paracetamol, and Phenylephrine hydrochloride, which are primarily used to treat common cold symptoms, allergies, and fever.
Wikoryl 325 mg DT Tablet is not an antibiotic. It contains a combination of a decongestant, antihistamine, and antipyretic. It does not target bacterial infections like an antibiotic would.
Wikoryl 325 mg DT Tablet is generally safe when used as directed by your doctor, especially for short-term use in people with common cold symptoms and allergies. However, you should inform your doctor if you have high blood pressure, diabetes, glaucoma, overactive thyroid (hyperthyroidism), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), an enlarged prostate, or any kidney, liver, heart, or urinary problems, before using Wikoryl 325 mg DT Tablet .
Wikoryl 325 mg DT Tablet may potentially harm your liver if taken in excessive doses or for a long time, especially if you have pre-existing liver problems. Please consult your doctor before using Wikoryl 325 mg DT Tablet , as your doctor may adjust the dosage if necessary.
Wikoryl 325 mg DT Tablet should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of reach of children.

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