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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:24 PM IST
Vostazole 100mg/200mg Tablet is used to treat bacterial infections, dysentery and diarrhoea. It contains furazolidone and metronidazole which kill the parasites and bacteria that cause infections. In some cases, this medicine may cause side effects such as nausea, dry mouth, headache, metallic taste, and discoloration of urine. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Vision Medilink

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ORAL

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About Vostazole 100mg/200mg Tablet

Vostazole 100mg/200mg Tablet belongs to a class of medicines known as antibiotics. This is used to treat various infections caused by bacteria, dysentery and diarrhea. A bacterial infection is a condition in which harmful bacteria enter, multiply and infect our bodies. It can target any body part and multiple very quickly. Amoebic dysentery can be caused due to entamoeba histolytica, giardia lamblia or clostridium difficile. Diarrhea is the increase in bowel movement leading to increased and loose motions.

Vostazole 100mg/200mg Tablet is a combination of two antibiotics that include furazolidone and metronidazole. Vostazole 100mg/200mg Tablet contains flurazolidone works by interfering with the protein synthesis, a mechanism which is important for survival of bacteria. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. Collectively they help in treating the disease effectively.

Take Vostazole 100mg/200mg Tablet as prescribed by your doctor. Your doctor will recommend how often you take Vostazole 100mg/200mg Tablet based on your medical condition. Some people may experience nausea, dryness in the mouth, headache, metallic taste, and dark yellow to brown discoloration of urine. Most of these side effects of Vostazole 100mg/200mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Vostazole 100mg/200mg Tablet should not be taken if you are allergic to Vostazole 100mg/200mg Tablet or any other contents present in it. It is not advisable to stop taking Vostazole 100mg/200mg Tablet suddenly to avoid unpleasant side effects. The full course prescribed by the doctor should be completed. Vostazole 100mg/200mg Tablet should not be taken in the conditions like a history of liver and kidney disease. It is advisable to you do not drive while using Vostazole 100mg/200mg Tablet as Vostazole 100mg/200mg Tablet may cause blurred vision or dizziness that may affect the ability to drive or using machines. Vostazole 100mg/200mg Tablet is safely given to children.

Uses of Vostazole 100mg/200mg Tablet

Treatment of Bacterial infection, Diarrhea, Dysentry, Intestinal infection.

Medicinal Benefits

Vostazole 100mg/200mg Tablet is a combination of two medicines namely furazolidone and metronidazole. is used to treat various infections caused by bacteria, dysentery and diarrhea. It is also used to treat intestinal infections, typhoid fever and skin infections. Vostazole 100mg/200mg Tablet is effective to treat many types of bacterial infections. Vostazole 100mg/200mg Tablet contains flurazolidone works by interfering with the protein synthesis, a mechanism which is important for survival of bacteria. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. Collectively they help in treating the disease effectively.

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Syrup/suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Vostazole 100mg/200mg Tablet

  • Nausea
  • Dizziness
  • Vomiting
  • Abdominal distress
  • Vertigo
  • Dryness in mouth
  • Headache
  • Metallic taste
  • Ototoxicity
  • Dark yellow to brown discoloration of urine

Drug Warnings

If you are allergic to furazolidone, metronidazole or any other antibacterial or anti amoebic agents, please inform your doctor to avoid any unwanted side-effects. Vostazole 100mg/200mg Tablet should not be taken in the conditions like liver disease, kidney disease. Before taking Vostazole 100mg/200mg Tablet inform your doctor if you have fits disorder, numbness or pain of feet or hands. Vostazole 100mg/200mg Tablet may low white blood cell count (leukopenia). Vostazole 100mg/200mg Tablet may cause convulsions (rapid contraction and relaxation of body muscles), if you observe these symptoms immediately contact your doctor. Discontinue the Vostazole 100mg/200mg Tablet if any signs of low blood count observed. Immediately inform your doctor if you experience swelling of the face, tongue, throat, itchy rash or breathing difficulties while taking this Vostazole 100mg/200mg Tablet. Vostazole 100mg/200mg Tablet is safely given to children above one month year of age. It is advisable to you do not drive while using Vostazole 100mg/200mg Tablet as Vostazole 100mg/200mg Tablet may cause blurred vision or dizziness that may affect the ability to drive or use machines. It is not advisable to stop taking Vostazole 100mg/200mg Tablet suddenly to avoid unpleasant side effects. The full course prescribed by the doctor should be completed.

Drug Interactions

Drug-Drug Interaction: This medicine may have an interaction with antiparkinson’s medicine (selegiline, rasagiline, apomorphine), a medicine used in cough (dextromethorphan), antiallergic (phenylephrine, pseudoephedrine), medicine for the fit disorder (phenobarbital), medicine for enlarged prostate gland (a gland between the bladder and penis) (alfuzosin), medicine for heart disease (amiodarone), antibiotic (clarithromycin), antacid (omeprazole).

Drug-Food Interaction: Vostazole 100mg/200mg Tablet interacts with foods with high tyramine. Avoid drinking alcohol as it may lead to an unpleasant reaction with symptoms like stomach pain, vomiting, nausea, flushing, headache or redness of the face.

Drug-Disease Interaction: Vostazole 100mg/200mg Tablet may interact in patients with liver disease and gastrointestinal disease.

Drug-Drug Interactions Checker List

  • SELEGILINE
  • RASAGILINE
  • APOMORPHINE
  • DEXTROMETHORPHAN
  • PHENYLEPHRINE
  • PSEUDOEPHEDRINE
  • PHENOBARBITAL
  • ALFUZOSIN
  • AMIODARONE
  • CLARITHROMYCIN
  • OMEPRAZOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Do not drink or eat a lot of caffeine-containing products such as coffee, tea, energy drinks, cola or chocolate. Vostazole 100mg/200mg Tablet may increase nervousness, sleeplessness and anxiety caused by caffeine.
  • Probiotics should be taken after taking the full course of Vostazole 100mg/200mg Tablet in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha and kimchi can help restore the intestine's good bacteria. 
  • Include more fiber-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet. Make sure you drink plenty of water or other fluids every day while you are taking Vostazole 100mg/200mg Tablet.
  • Avoid intake of alcoholic beverages with Vostazole 100mg/200mg Tablet as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Vostazole 100mg/200mg Tablet in fighting off infections.

Special Advise

You should consult a doctor if you have symptoms associated with dehydration like dry mouth, excessive thirst, wrinkled skin, little or no urination, dizziness and lightheadedness.

Disease/Condition Glossary

Bacterial Infection: A bacterial infection is a condition in which harmful bacteria enter, multiply and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills and fatigue. Bacteria are of various forms comprising commonly of spherical, rod and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus and E. coli. Anyone can become infected with a bacterial infection. People with weak immune systems or taking immunosuppressive medicine can make them more prone to bacterial infection.

Diarrhea: It is the increase in bowel movement leading to increased and loose motions. 

Dysentery: It is inflammation of the intestine, particularly the colon, caused by the bacteria Shigella.

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Alcohol

Unsafe

Drinking alcohol while taking this Vostazole 100mg/200mg Tablet may lead to an unpleasant reaction with symptoms like stomach pain, vomiting, nausea, flushing, headache or redness of the face.

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Pregnancy

Unsafe

Vostazole 100mg/200mg Tablet should not be taken if you are pregnant or planning to have a baby. If you become pregnant while taking Vostazole 100mg/200mg Tablet, stop taking the medication, and contact your doctor immediately. Metronidazole should not be given in the first trimester of the pregnancy as it may cause harm to the fetus.

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Breast Feeding

Caution

Take Vostazole 100mg/200mg Tablet only when prescribed, Vostazole 100mg/200mg Tablet contains ‘metronidazole’ which is known to pass on in a limited quantity via breast milk to the child. Consult your doctor for further advice.

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Driving

Caution

Do not drive while using Vostazole 100mg/200mg Tablet as Vostazole 100mg/200mg Tablet may cause blurred vision or dizziness that may affect the ability to drive or using machines.

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Liver

Caution

Vostazole 100mg/200mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Vostazole 100mg/200mg Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Vostazole 100mg/200mg Tablet can be given to the children for typhoid fever, diarrhea, a stomach infection, amoebiasis, abdominal infection, diarrhea and intestinal infection only when prescribed by a child specialist.

Country of origin

India
Other Info - VO17337

Author Details

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FAQs

Vostazole 100mg/200mg Tablet is used to treat bacterial infections, dysentery and diarrhoea. It works by killing infection-causing organisms.
Yes, Vostazole 100mg/200mg Tablet is known to cause dry mouth, especially when you start taking Vostazole 100mg/200mg Tablet. If you feel excessively thirsty, do frequent mouth rinses, and increase fluid intake.
Vostazole 100mg/200mg Tablet helps in the treatment of various bacterial infections, diarrhea, and dysentery. Vostazole 100mg/200mg Tablet contains flurazolidone works by interfering with the protein synthesis, a mechanism which is important for survival of bacteria. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It works by damaging their DNA. Collectively they help in treating the disease effectively.
Yes, Vostazole 100mg/200mg Tablet may lead to temporary metallic taste. This metallic taste can be reduced by chewing mints, sugar-free gum and brushing teeth after the food.
No, do not stop taking Vostazole 100mg/200mg Tablet and complete the full course of treatment even if you feel well. Your symptoms may enhance before the infection is completely treated.
Yes, Vostazole 100mg/200mg Tablet may cause nausea and vomiting in some patients. You are recommended to take Vostazole 100mg/200mg Tablet with meals to avoid this. If you still vomit or feel nauseous, please consult your doctor.
No, you are recommended not to take Vostazole 100mg/200mg Tablet with other antibiotics. Vostazole 100mg/200mg Tablet is an antibiotic medicine that is used to treat parasitic and amoebic infections. When taken along with other antibiotics, Vostazole 100mg/200mg Tablet may lose its efficiency or it might result in unwanted side effects.
Drinking alcohol while taking this Vostazole 100mg/200mg Tablet may lead to an unpleasant reaction with symptoms like stomach pain, vomiting, nausea, flushing, and headache. So, It is important to avoid alcohol consumption during the treatment with Vostazole 100mg/200mg Tablet.
Store Vostazole 100mg/200mg Tablet in a cool and dry place away from sunlight. Keep it out of the reach of children. Regularly check the expiration date. When you need to dispose of the medicine, place it in a plastic bag and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink.
The common side effects of Vostazole 100mg/200mg Tablet which may occur in some individuals are nausea, dryness in the mouth, headache, metallic taste, and dark yellow to brown discoloration of urine. Most of these side effects do not require medical attention and gradually resolve over time. However, if these side effects persist or worsen, please consult your doctor.

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