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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 26, 2024 | 7:08 PM IST

Volix Trio DS 1 Tablet is used to treat type 2 diabetes mellitus. It acts by increasing the amount of insulin released by the pancreas. Thus, prevent the blood glucose levels from rising to very high levels and keeps your diabetes under control. It may cause certain common side effects such as hypoglycaemia (low blood glucose levels), taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Synonym :

GLIMEPIRIDE+METFORMIN HYDROCHLORIDE+VOGLIBOSE

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Volix Trio DS 1 Tablet

Volix Trio DS 1 Tablet is a combination of anti-diabetic drugs used to treat type 2 diabetes mellitus. Type 2 diabetes is a chronic or lifelong condition that affects the way your body processes glucose. The blood glucose level increases and causes symptoms such as frequent urination, increased thirst, and increased hunger; hence, people with type 2 diabetes either do not produce enough insulin or, if at all the insulin is produced, it is unable to perform its function in the body (insulin resistance). 

Volix Trio DS 1 Tablet is a combination of three antidiabetic drugs: Glimepiride, Metformin and Voglibose. Glimepiride, which is a 'sulfonylurea', acts by increasing the amount of insulin released by the pancreas. Together, these prevent the blood glucose levels from rising to very high levels, thus keeping your diabetes under control.

Volix Trio DS 1 Tablet should be taken with food to avoid an upset stomach. Based on your medical condition, your doctor will decide for how long you need to take Volix Trio DS 1 Tablet . Volix Trio DS 1 Tablet may cause certain common side effects such as hypoglycaemia (low blood glucose levels), taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms. Most of these side effects do not require medical attention and will resolve gradually over time; however, if you experience these side effects persistently, consult your doctor.

Do not stop taking Volix Trio DS 1 Tablet without consulting your doctor, as abrupt stopping may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Volix Trio DS 1 Tablet should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any type of heart disease, are planning to get pregnant or are breastfeeding.

Uses of Volix Trio DS 1 Tablet

Treatment of Type 2 diabetes mellitus

Medicinal Benefits

Volix Trio DS 1 Tablet contains Glimepiride, Metformin and Voglibose. Glimepiride, which is a 'sulfonylurea', acts by increasing the amount of insulin released by the pancreas. Metformin, which is a 'biguanide', acts by lowering the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's response to insulin. Voglibose, which is an 'alpha-glucosidase inhibitor', prevents the breakdown of complex sugars into simple sugars such as glucose in the intestine. Volix Trio DS 1 Tablet prevents the blood glucose levels from rising to very high levels, thus keeping your diabetes under control. Volix Trio DS 1 Tablet also helps to prevent serious complications of diabetes such as kidney damage (Diabetic Nephropathy), blindness (Diabetic Retinopathy), loss of sensation in your hands and feet (Diabetic Neuropathy), Volix Trio DS 1 Tablet also helps to reduce your chance of having a heart attack or stroke. Being a combination of three drugs, Volix Trio DS 1 Tablet  reduces the need to take multiple pills and hence makes it easier to remember to take the drugs.

Side Effects of Volix Trio DS 1 Tablet

  • Hypoglycaemia (low blood glucose level) 
  • Taste change
  • Nausea
  • Diarrhoea
  • Stomach pain
  • Flatulence
  • Headache
  • Upper respiratory symptoms

Directions for Use

Swallow it as a whole with a glass of water. Do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Some diabetic patients taking Volix Trio DS 1 Tablet may develop a rare but serious condition called lactic acidosis. In this condition, too much lactic acid accumulates in the blood. So, your liver and kidney's proper functioning is required for the elimination of excess lactic acid from the blood. You should not take Volix Trio DS 1 Tablet if you have kidney disease, as measured by a blood test. Volix Trio DS 1 Tablet may lower vitamin B12 levels, so try to have blood tests annually blood and vitamins. Volix Trio DS 1 Tablet , when used with or without insulin, has the tendency to extremely lower the blood sugar level. So, the doctor may lower the dose of insulin. Volix Trio DS 1 Tablet may lower your thyroid-stimulating hormone (TSH), so an annual check-up of TSH is suggested.

Therapeutic Class

ANTIDIABETICS

Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, quarter with proteins and quarter with whole grain.
  • Eat at regular intervals. Do not take the long gap between a meal or snack.
  • Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
  • Invest in at least 150 min of moderate-intensity physical activity and 15 minutes of high-intensity exercise every week.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates-containing foods with wholegrain foods and increase intake of fruits and veggies and other fibre-enriched foods.
  • Reduce intake of saturated fat (or hidden fats) in the food like chips, crisps, pastries, biscuits and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil and safflower oil.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk and cheese etc.).
  • Keep your blood pressure as normal (120/80) as possible. As it reduces the risk of cardiovascular diseases in diabetes patients.

Habit Forming

No

What if I have taken an overdose of Volix Trio DS 1 Tablet

Do not take more than the prescribed dose of Volix Trio DS 1 Tablet as it may cause overdose resulting in mild hypoglycemia (low blood sugar). If you suspect you have taken overdose or have symptoms of overdose, please consult a doctor immediately.
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Alcohol

Unsafe

Taking Volix Trio DS 1 Tablet with alcohol can cause hypoglycaemia and can also lead to a rare but life-threatening condition known as Lactic Acidosis. So, keep your doctor informed if you drink alcohol.

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Pregnancy

Caution

As the data around the use of Volix Trio DS 1 Tablet in pregnant women is limited, the use of Volix Trio DS 1 Tablet in pregnancy is restricted. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

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Breast Feeding

Caution

The name is not recommended during breastfeeding. However, your doctor may prescribe it for you during breastfeeding if he/she feels that the benefit to you outweighs the risk. You should not take Volix Trio DS 1 Tablet without a doctor's advice.

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Driving

Caution

Volix Trio DS 1 Tablet may cause hypoglycaemia (low blood sugar levels) whose symptoms include unusual sleepiness, shivering, palpitations, sweating etc. This may affect your ability to drive. Use caution while driving or doing anything that requires concentration.

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Liver

Caution

Volix Trio DS 1 Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor depending on your liver function tests.

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Kidney

Caution

Volix Trio DS 1 Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor depending on your kidney function tests.

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Children

Caution

Volix Trio DS 1 Tablet is not recommended for children below the age of 18 years. The safety and effectiveness of Volix Trio DS 1 Tablet has not been established in children due to limited evidence. So, only take Volix Trio DS 1 Tablet if the doctor has prescribed Volix Trio DS 1 Tablet .

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - VOL0384

Author Details

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FAQs

Volix Trio DS 1 Tablet is a combination of anti-diabetic drugs used to treat type 2 diabetes mellitus.
If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing and frequent infections, contact doctor as it can be a condition of type 2 diabetes.
Hypoglycaemia refers to low blood sugar levels. The symptoms of hypoglycaemia include nausea, headache, irritability, hunger, sweating, dizziness. Volix Trio DS 1 Tablet can cause hypoglycaemia. Hypoglycaemia can occur if you miss or delay your food, drink alcohol, over-exercise or take other anti-diabetic medicine along with Volix Trio DS 1 Tablet . Diabetics are advised to keep a quick source of sugar like glucose tablets, honey or fruit juice with them.
Volix Trio DS 1 Tablet should be avoided in patients who are allergic to any of the components or excipients of this medicine. It should be avoided in patients suffering from moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.
If you feel thirsty after taking Volix Trio DS 1 Tablet , it may be because of dehydration as Volix Trio DS 1 Tablet can lead to loss of fluids. Increase intake of fluids, if even then you feel thirsty please consult your doctor.
If you have been affected with diabetes, you should have a test of HbA1c once in three months.
Yes, long-term usage of Volix Trio DS 1 Tablet can cause vitamin B12 deficiency as it interferes with the absorption of vitamin B12 in the stomach. The symptoms can be managed by taking Vitamin B12 supplements as advised by your doctor.
No. Till date there is no clinical evidence that states that Volix Trio DS 1 Tablet affects fertility in either men or women.
Lactic acidosis is rare but life threatening condition when, there is too much of lactic acid build up in the bloodstream. Long term intake of Volix Trio DS 1 Tablet may lead to lactic acidosis when cells get deprived of the oxygen levels. Symptoms of lactic acidoisis includes burning sensation of muscle, muscle ache, fast breathing, nausea and stomach pain. Immediately contact doctor if you experience any of these symptoms when on Volix Trio DS 1 Tablet .
In case you feel that your blood sugar level is going down and you are feeling weak, immediately eat sugar candies or drink sugar beverages. It will help to balance blood sugar level in your body. So, it is advisable to keep sugar candies with you and consult a doctor immediately.
Follow a diet rich in fibre, low in fat with sufficient carbohydrates, protein, vitamins and minerals. Maintain the regular meal timings and try to have 2-3 healthy snacks between meals such as salads and soups. Use edible oils moderately and drink at least 8-10 glasses of water every day.
You are recommended to avoid white bread, maida, poori, naan, noodles, biryani, fried rice, carrot juice, soups, deep-fried vegetables, creams and vegetable curries with excess oil. Also, avoid mango, seetaphal, jack fruit, fruit salads with ice cream, and fruit-based desserts. Avoid overeating. Avoid shopping when you are hungry. You could be tempted to purchase oil and fried food.
Volix Trio DS 1 Tablet acts by encouraging insulin secretion from the β-cells of the pancreas and increase the amount of insulin released by the pancreas. Also, it helps to restore the body's proper response to the insulin it naturally produces.
The symptoms of diabetes include increased hunger, increased urine frequency, and increased thirst. To know the exact condition, your doctor may recommend blood tests, such as fasting blood glucose, post-meal blood glucose and HbA1C.
Store Volix Trio DS 1 Tablet at room temperature. Protect from light and moisture. Keep it out of reach of children.
Volix Trio DS 1 Tablet may cause side effects such as hypoglycemia (low blood sugar level), taste change, stomach pain, nausea, diarrhea, and headache. If these side effects persist or worsen, please consult your doctor.
No, it is not safe to take alcohol while taking Volix Trio DS 1 Tablet as it may cause hypoglycaemia (low blood sugar) and can also lead to a rare but life-threatening condition known as Lactic Acidosis.

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