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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Unicristin 1 mg Injection 1 ml is an anti-cancer drug used to treat various types of cancer such as cancer of the breast, pancreas, kidney, blood, bone and lung. It contains Vincristine, which stops the further growth and multiplication of the cancer cells. It may cause side effects such as hair loss, constipation, headache, tingling and numbness of feet and hand, stomach cramps, feeling tired or weak, back, bone, joint, or muscle pain, mouth irritation, or mouth sores.
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Prescription drug

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Prescription drug
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Composition

VINCRISTINE-1MG

Manufacturer/Marketer

United Biotech Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Unicristin 1 mg Injection 1 ml

Unicristin 1 mg Injection 1 ml belongs to a class of drugs known as 'anti-cancer medication,' primarily used to treat various types of cancer. It is used to treat cancer of the breast, pancreas, kidney, blood, bone, lung. Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are more than 100 types of cancer, including blood cancer, lung cancer, breast cancer.

Unicristin 1 mg Injection 1 ml contains Vincristine, which is primarily used to treat cancer. It works by blocking the replication of DNA (genetic material) in the cancer cells. Hence, this stops the further growth and multiplication of the cancer cells. 

Take Unicristin 1 mg Injection 1 ml as prescribed by your doctor. You are advised to take Unicristin 1 mg Injection 1 ml for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience hair loss, constipation, headache, peripheral neuropathy (tingling and numbness of feet and hand), stomach cramps, feeling tired or weak, back, bone, joint, or muscle pain, mouth irritation, or mouth sores. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently. 

Do not take Unicristin 1 mg Injection 1 ml if you are allergic to Unicristin 1 mg Injection 1 ml or any of its ingredients. Unicristin 1 mg Injection 1 ml is a pregnancy category D drug, so it should not be used in pregnant women or if you are planning for pregnancy as Unicristin 1 mg Injection 1 ml causes serious congenital disabilities. You should use an effective way for birth control to avoid pregnancy (both men and women) while taking Unicristin 1 mg Injection 1 ml. Avoid consuming alcohol along with Unicristin 1 mg Injection 1 ml as it could lead to increased dizziness. Unicristin 1 mg Injection 1 ml may make you more susceptible to infections; consult your doctor if you develop any signs of fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. 

Uses of Unicristin 1 mg Injection 1 ml

Treatment of Various types of cancer

Medicinal Benefits

Unicristin 1 mg Injection 1 ml contains Vincristine, an anti-cancer medicine used to treat various types of cancer. It is used to treat cancers of the blood (leukemia or lymphomas), breast, head and neck or lung. It may be used to treat multiple myeloma (a cancer of plasma cells), and it may also be used in the treatment of some cancers in children. It is also used in a blood disorder known as idiopathic thrombocytopenic purpura (ITP) after another medication has become unsuccessful in treating it.

Directions for Use

Unicristin 1 mg Injection 1 ml comes in injection form. So, it should be administered by a doctor or trained professional at a hospital. Never self administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Unicristin 1 mg Injection 1 ml

  • Constipation
  • Headache
  • Hair loss
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Stomach cramps
  • Feeling tired or weak
  • Mouth irritation or mouth sores
  • Back, bone, joint, or muscle pain

Drug Warnings

Do not take Unicristin 1 mg Injection 1 ml if you are allergic to Unicristin 1 mg Injection 1 ml or any of its ingredients. You should use an effective way for birth control to avoid pregnancy (both men and women) while taking Unicristin 1 mg Injection 1 ml. Do not take Unicristin 1 mg Injection 1 ml if you are pregnant or planning for pregnancy as Unicristin 1 mg Injection 1 ml causes serious congenital disabilities. Unicristin 1 mg Injection 1 ml should not be taken by breastfeeding mothers as it is not known whether it passes through breast milk or not. Talk to your doctor before taking Unicristin 1 mg Injection 1 ml if you have/had liver or kidney problems, ulceration in stomach or bowels, poor general condition, received any vaccinations or if are due to have any, diabetes mellitus treated with insulin. Unicristin 1 mg Injection 1 ml causes dizziness and drowsiness, so drive with caution. Unicristin 1 mg Injection 1 ml should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Unicristin 1 mg Injection 1 ml as it could lead to increased dizziness. Unicristin 1 mg Injection 1 ml may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. 

Drug Interactions

  • Drug-Drug Interaction: Unicristin 1 mg Injection 1 ml is known to interact in patients with Charcot-Marie-Tooth syndrome (a disease that causes weakness in the leg muscles), mental disorder, liver or kidney problem, radiotherapy, breathing problems (asthma), low white blood cell.
  • Drug-Food Interaction: Unicristin 1 mg Injection 1 ml is known to interact with the St. John Wort plant (a natural remedy to treat depression).
  • Drug-Drug Interaction: $nmae is known to interact with anti-tuberculosis medicine (isoniazid), anti-cancer medicine (mitomycin, asparaginase, dactinomycin), anti-fungal medicines (itraconazole, fluconazole).

Drug-Drug Interactions Checker List

  • ISONIAZID
  • DACTINOMYCIN
  • ITRACONAZOLE
  • FLUCONAZOLE
  • ASPARAGINASE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listen to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, and high fiber content. Also, eat small and frequent meals for a speedy recovery.
  • Avoid smoking and alcohol consumption. Also, avoid high fat and cholesterol diet.

Special Advise

  • Regularly monitor your blood cell count, platelet count and liver function.
  • If you see any redness, pain, swelling, burning, skin sores, or leaking of fluid from where the drug is going into your body, please tell your nurse as this could mean that Unicristin 1 mg Injection 1 ml is not being administered properly which could lead to tissue damage.

Disease/Condition Glossary

Cancer: It is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer, namely benign (localized) and metastatic (spread to the whole body). There are more than 100 types of cancer, including blood cancer, lung cancer, breast cancer. Cancer growth can be prevented by chemotherapy, radiation, stem cell therapy and by doing surgical excision.

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Alcohol

Caution

Avoid consumption of alcohol while taking Unicristin 1 mg Injection 1 ml as it may increase drowsiness.

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Pregnancy

Unsafe

Unicristin 1 mg Injection 1 ml is a pregnancy category D drug. It should not be used in pregnancy as it is known to cause fetal damage. Also, maintain a gap of 6 months between the last dose of Unicristin 1 mg Injection 1 ml and your next pregnancy.

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Breast Feeding

Unsafe

Unicristin 1 mg Injection 1 ml is known to pass through breast milk and it may cause harm to the baby. So, it is advised not to breastfeed while taking Unicristin 1 mg Injection 1 ml.

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Driving

Unsafe

Unicristin 1 mg Injection 1 ml may cause weakness, dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

The safety and efficacy of Unicristin 1 mg Injection 1 ml are not known in children. It should be taken only if prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044.
Other Info - UNI0024

Author Details

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FAQs

Unicristin 1 mg Injection 1 ml is used to treat various types of cancer. It is used to treat cancer of the breast, pancreas, kidney, blood, bone, lung.
Unicristin 1 mg Injection 1 ml contains Vincristine, which works by blocking DNAÂ replication (genetic material) in the cancer cells. Hence, this stops the further growth and multiplication of the cancer cells.Â
Unicristin 1 mg Injection 1 ml if not administered properly, and if it leaks from the vein, it may cause tissue damage. So, if you see any redness, pain, swelling, burning, skin sores or leaking of fluid from where the drug is going into your body, please tell your nurse.
The most common side effects of Unicristin 1 mg Injection 1 ml are hair loss, constipation, headache, peripheral neuropathy (tingling and numbness of feet and hand), stomach cramps, feeling tired or weak, back, bone, joint or muscle pain, mouth irritation or mouth sores​​​​​​​. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.Â
Unicristin 1 mg Injection 1 ml is a vesicant (irritant) and can damage the tissues and blood vessels if it is not administered correctly, which can be fatal. So, it should be given by a trained professional in the hospital.
Yes, Unicristin 1 mg Injection 1 ml is a cytotoxic (toxic to living cells) medicine. So, it is advised to be very cautious while taking Unicristin 1 mg Injection 1 ml.

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