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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:19 PM IST

Uniblastin 10mg Injection is used to treat cancer. It contains Vinblastine, which works by preventing cancer cells from dividing into two new cells. As a result, it prevents the cancer from spreading. This medication can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months afterwards. Before beginning treatment, discuss effective contraception with your healthcare professional. Inform them immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment since it is unknown whether this medication passes into breast milk.

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Prescription drug

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Synonym

VINBLASTINE SULFATE

Composition

VINBLASTINE-10MG

Manufacturer/Marketer

United Biotech Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Uniblastin 10mg Injection

Uniblastin 10mg Injection belongs to a class of vinca alkaloids, also known as chemotherapeutic agents. It is used to treat various cancer conditions such as Hodgkin's disease, certain forms of non-Hodgkin's lymphoma, testicular carcinoma, lymphocytic lymphoma, breast cancer, and ovarian cancer. Cancer is a genetic change in which the body's cells divide uncontrollably and spread into surrounding tissues.

Uniblastin 10mg Injection contains Vinblastine, which works by preventing cancer cells from dividing into two new cells. As a result, it prevents the cancer from spreading.

Uniblastin 10mg Injection should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents. The most common adverse reactions are a drop in blood cells and platelets, feeling sick (nausea), being sick (vomiting), sores in the mouth and throat, and tiredness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if any of these side effects persist or worsen.

It is recommended not to use if you are allergic to any ingredient in Uniblastin 10mg Injection. Uniblastin 10mg Injection can cause fetal harm when administered to a pregnant woman. It is critical not to become pregnant or get pregnant while undergoing therapy and for several months afterwards. Before beginning treatment, discuss effective contraception with your healthcare professional. Inform them immediately if you or your partner becomes pregnant while undergoing therapy. Breastfeeding is usually not advised during this treatment since it is unknown whether this medication passes into breast milk. Alcohol should be avoided during treatment with this medicine. Drive only if alert, as the Uniblastin 10mg Injection may cause drowsiness or dizziness.

Uses of Uniblastin 10mg Injection

Treatment of Cancer

Medicinal Benefits

Uniblastin 10mg Injection belongs to a class of vinca alkaloids, also known as a chemotherapeutic agent, primarily used to treat various cancer conditions. Vinblastine, present in Uniblastin 10mg Injection, prevents cancer cells from dividing into two new cells. As a result, it prevents the cancer from spreading.

Directions for Use

Uniblastin 10mg Injection should only be given to patients in a hospital setting under the supervision of a physician who is trained and experienced in the administration of cancer chemotherapeutic drugs.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Uniblastin 10mg Injection

  • Injection site reactions
  • A drop in the number of blood cells and platelets
  • Vomiting
  • constipation
  • diarrhoea
  • anorexia
  • abdominal pain
  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Diarrhoea
  • Mouth ulcers
  • Hair loss

Drug Warnings

Before taking Uniblastin 10mg Injection, inform your doctor about your medical history and ongoing therapies to rule out potential adverse effects or interactions. It's crucial to take your medication as directed. The dosage of this medicine is based on your condition. Your doctor may adjust your dose during therapy based on the treatment results. The drug Vinblastine can reduce the number of blood cells. Your doctor will request laboratory testing before, during, and after therapy to determine whether this drug affects your blood cells. Keep all lab appointments. Uniblastin 10mg Injection is recommended not to be used in pregnant women or nursing mothers; if you become pregnant while on treatment with Vinblastine, tell your doctor right away.

Drug Interactions

Drug-Drug Interactions: Uniblastin 10mg Injection may interact with vaccines (e.g. BCG vaccine, Mumps virus vaccine, Influenza virus vaccine), cancer medications (e.g. Adalimumab), schizophrenia medications (e.g. Clozapine), medicines used to treat moderate to severe plaque psoriasis (e.g. Deucravacitinib), medications used to treat Multiple Sclerosis (e.g. Cladribine), medicines used to manage and treat autoimmune conditions (e.g. Etanercept), immunomodulating drugs (e.g. Fingolimod) and antirheumatic drug (e.g. Leflunomide).

Drug-Food Interactions: Avoid the consumption of alcoholic beverages.

Drug-Disease Interactions: Uniblastin 10mg Injection may interact with disease conditions, including infections, myelosuppression (bone marrow doesn't make enough blood cells or platelets), pulmonary Impairment and hepatic dysfunction.

Drug-Drug Interactions Checker List

  • BCG VACCINE
  • MUMPS (LIVE ATTENUATED)
  • INFLUENZA VIRUS VACCINE
  • ADALIMUMAB
  • CLOZAPINE
  • DEUCRAVACITINIB
  • CLADRIBINE
  • ETANERCEPT
  • FINGOLIMOD
  • LEFLUNOMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Special Advise

  • When you take Uniblastin 10mg Injection, your doctor will suggest regular blood tests to monitor the count of blood cells.

Disease/Condition Glossary

Cancer: Cancer is a genetic change in which the body's cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Types of cancer include blood, lung, breast, etc. Cancer growth can be prevented by chemotherapy, radiation, and stem cell therapy.

Hodgkin's disease: Hodgkin lymphoma, commonly known as Hodgkin's disease, is a kind of cancer that affects the lymphatic system. Your lymphatic system is a component of your immune system. It aids in the defence of your body against infection and sickness. The lymph system comprises tissues and organs that generate, store, and transport white blood cells.

Testicular carcinoma: Testicular cancer is a type of cancer that begins in the testicles. The testicles, commonly known as testes, are located in the scrotum. Testicular carcinoma is a rare kind of cancer. It can occur at any age; however, it most commonly occurs between the ages of 15 and 45. A bulge or lump on a testicle is frequently the first sign of testicular cancer. Cancer cells can multiply swiftly. They frequently spread to other regions of the body from the testicle.

Lymphocytic leukaemia: The most prevalent type of leukaemia in adults is chronic lymphocytic leukaemia (CLL). It is a form of cancer that begins in the bone marrow in cells that develop into specific white blood cells (called lymphocytes). Cancer (leukaemia) cells begin in the bone marrow and subsequently spread to the blood.

Breast Cancer: Breast cancer is a type of cancer that develops in breast cells. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and can travel to lymph nodes, a primary pathway for the cancer cells to move to other body parts.

Ovarian cancer: Ovarian cancer begins in the ovaries (one of a pair of female reproductive glands in which the ova, or eggs, are formed). Advanced ovarian cancer indicates that the cancer has progressed beyond the ovary. It could have spread within the pelvis or abdomen or gone to other body parts, such as the lungs.

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Alcohol

Caution

Avoid alcohol consumption while on treatment with Uniblastin 10mg Injection as it may cause serious side effects.

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Pregnancy

Unsafe

Uniblastin 10mg Injection is not recommended for use during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Unsafe

Uniblastin 10mg Injection should not be used in breastfeeding. Discuss with your doctor if you have any concerns.

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Driving

Caution

Drive only if alert, as the Uniblastin 10mg Injection may cause drowsiness or dizziness.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Uniblastin 10mg Injection. Your doctor will weigh the benefits and potential risks before prescribing Uniblastin 10mg Injection.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Uniblastin 10mg Injection. Your doctor may titrate the dose if required based on your condition.

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Children

Safe if prescribed

Uniblastin 10mg Injection can be used to treat certain cancers in children. Please consult your doctor for more information.

Country of origin

India

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Other Info - UNI0020

Author Details

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FAQs

Uniblastin 10mg Injection is used to treat Cancer.
Vinblastine, present in Uniblastin 10mg Injection, works by preventing cancer cells from dividing into two new cells. As a result, it prevents the cancer from spreading.
Attend all your doctor's appointments while taking Uniblastin 10mg Injection to ensure the therapy is effective. Regular blood tests and weight checks must be performed. While taking the Uniblastin 10mg Injection, both men and women should use an effective means of contraception. Do not use any other medications unless prescribed by the doctor.
Do not stop taking Uniblastin 10mg Injection on your own. Take Uniblastin 10mg Injection for as long as your doctor prescribes it, depending on your medical condition. Do not hesitate to speak with your doctor if you experience difficulty taking Uniblastin 10mg Injection.
Vinblastine can cause a significant decrease in the number of blood cells and platelets. Your doctor may suggest laboratory tests before and during the treatment.
Some dietary changes can help you manage side effects; for example, in case of diarrhoea-Choose foods or drinks with sodium (sports drinks or broth) and potassium (bananas and all-natural fruit juices).
It is unknown whether it can be irritating or not. Uniblastin 10mg Injection is a chemotherapeutic agent. However, if it is bothering you after taking Uniblastin 10mg Injection consult your doctor for guidance.
Generally, Uniblastin 10mg Injection is administered intravenously. However, Uniblastin 10mg Injection should only be given to patients in a hospital setting under the supervision of a physician who is trained and experienced in the administration of cancer chemotherapeutic drugs.
Uniblastin 10mg Injection may cause hair loss and does not have the potential to cause infertility. However, if you experience any of these symptoms consult your doctor immediately.
Uniblastin 10mg Injection works by stopping cells from dividing by interfering with the formation of microtubules, which are essential for cell division.

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