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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 26, 2024 | 7:08 PM IST
Twigan 20mg/500mg Tablet is used in the treatment of spasmodic pain and discomfort due to biliary colic, intestinal colic, renal colic and spasmodic dysmenorrhea (painful, irregular periods). It also helps reduce the symptoms of irritable bowel syndrome (IBS). It contains Dicyclomine and Paracetamol, which helps in blocking the activity of certain natural substances that are responsible for causing pain. It may cause common side effects such as dizziness, nausea (feeling sick), digestion problems like constipation, flatulence, diarrhoea, and skin reactions like rashes and hives. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Vision Medilink

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Twigan 20mg/500mg Tablet

Twigan 20mg/500mg Tablet is used in the treatment of spasmodic pain and discomfort due to biliary colic, intestinal colic, renal colic and spasmodic dysmenorrhea (painful, irregular periods). It also helps alleviate the symptoms of irritable bowel syndrome (IBS). Colic is the intensive and uncontrollable crying in babies for a prolonged period for no certain reason. Dysmenorrhea (Abdominal cramps) is an unpleasant sensory and emotional experience associated with irregular periods. It occurs just before or during menses. Irritable bowel syndrome is an intestinal disorder that causes stomach pain, wind, constipation, and diarrhoea.

Twigan 20mg/500mg Tablet is composed of two medicines: Dicyclomine (antispasmodic/anticholinergic agent) and Paracetamol (analgesic). Dicyclomine/Dicycloverine helps in blocking the activity of certain natural substances that are responsible for causing pain. Paracetamol has both analgesic (pain reducer) and antipyretic (fever reducer) properties, which also decrease inflammation.

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Twigan 20mg/500mg Tablet include experiencing dizziness, nausea (feeling sick), digestion problems like constipation, flatulence, diarrhoea, and skin reactions like rashes and hives. Most of the side effects of Twigan 20mg/500mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you are sensitive or allergic to Twigan 20mg/500mg Tablet or any other medications. Before using Twigan 20mg/500mg Tablet, let your doctor know if you have liver, kidney or heart diseases and any other medical history. Some antacids may inhibit the absorption of Twigan 20mg/500mg Tablet, hence consult your doctor. Twigan 20mg/500mg Tablet may cause dizziness; hence, do not drive or operate machinery until you feel better. Pregnant and breastfeeding women should consult their doctor before using Twigan 20mg/500mg Tablet. Twigan 20mg/500mg Tablet should be used in children only when recommended by a doctor.

Uses of Twigan 20mg/500mg Tablet

Treatment of Biliary colic, intestinal colic, renal colic, spasmodic dysmenorrhea, and symptoms of irritable bowel syndrome.

Medicinal Benefits

Twigan 20mg/500mg Tablet is composed of two medicines: Dicyclomine (antispasmodic) and Paracetamol (mild analgesic and fever reducer). Twigan 20mg/500mg Tablet helps relieve spasmodic pain and discomfort due to biliary colic, intestinal colic, renal colic, and spasmodic dysmenorrhea (painful irregular menses/periods). Dicyclomine helps in blocking the activity of certain natural substances in the body responsible for causing pain. On the other hand, Paracetamol has analgesic (pain reducer) and antipyretic (fever reducer) properties, decreasing inflammation. Together, they effectively reduce pain and inflammation in conditions of intestine inflammation, spasms and painful menstruation.

Directions for Use

Swallow Twigan 20mg/500mg Tablet as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Twigan 20mg/500mg Tablet

  • Dizziness

  • Nausea (feeling sick)

  • Constipation

  • Flatulence

  • Diarrhoea

  • Rashes/hives

Drug Warnings

Let your doctor know if you are sensitive to Twigan 20mg/500mg Tablet or its components. Twigan 20mg/500mg Tablet should be used with caution and only under a doctor’s supervision if you have stomach/intestinal problems and diarrhoea due to intestine surgeries like ileostomy and colostomy. Pregnant and breastfeeding women should use Twigan 20mg/500mg Tablet with proper consultation and caution. Twigan 20mg/500mg Tablet may cause blurry vision and dizziness affecting your mental focus, hence do not drive or operate machinery until you feel better. Drinking alcohol may worsen the side effects; therefore, it is advised to avoid the alcohol intake while using Twigan 20mg/500mg Tablet. Twigan 20mg/500mg Tablet should be used in children only when prescribed by the doctor.

Drug Interactions

Drug-Drug Interaction: Twigan 20mg/500mg Tablet may interact with cholesterol-lowering drugs (cholestyramine), vomiting medicines (domperidone), anti-HIV drugs (zidovudine), blood thinners (warfarin), corticosteroids, blood pressure-lowering medicines, drugs to lower organ rejection (tacrolimus), anti-cancer or anti-arthritis drugs (methotrexate), urinary alkalinizer (potassium citrate), and potassium supplements.

Drug-Food Interaction: Intake of alcohol should be avoided while taking Twigan 20mg/500mg Tablet.

Drug-Disease Interaction: Patients affected with liver disease, bleeding disorder, urinary tract infection (UTI), myasthenia gravis, high blood pressure, and alcoholism should seek medical advice before starting Twigan 20mg/500mg Tablet.

Drug-Drug Interactions Checker List

  • CHOLESTYRAMINE
  • DOMPERIDONE
  • ZIDOVUDINE
  • WARFARIN
  • TACROLIMUS
  • METHOTREXATE
  • POTASSIUM CITRATE

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid or limit the intake of alcohol and caffeine.

  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.

  • Limit taking high fibre foods, foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods. 

  • Do not have large meals at a time, instead try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.

  • Practice yoga and recreation techniques to manage your emotional stress.

  • If you are lactose intolerant, avoid using dairy products since it can worsen your IBS.

  • If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.

  • Drink plenty of fluids and dress lightly to prevent heatstroke and dehydration.

  • Avoid overly sweating activities like hard exercises and using hot tubs.

Disease/Condition Glossary

Colic: Colic is the intensive and uncontrollable crying in babies for a prolonged period for no certain reason. Colicky babies usually have distended bellies, release gas, raise their legs to the chest, and bend or arch their backs.

Irritable Bowel Syndrome (IBS): It is also termed as IBS colitis, mucous colitis, spastic colon, nervous colon, and spastic bowel. It is an inflammatory bowel disease that affects the large intestine. Symptoms of an IBS include abdominal pain, bloating, diarrhoea, mucus in stools, wind, constipation, tiredness, anxiety, depression, heartburn, indigestion, and headaches.

Dysmenorrhea refers to abdominal cramps/pain and an unpleasant sensory/emotional experience associated with irregular periods. It occurs just before or during menses. 

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Alcohol

Caution

It is advised to limit alcohol intake to prevent any undesirable side effects of Twigan 20mg/500mg Tablet and further worsen your disease. Please consult your doctor before using Twigan 20mg/500mg Tablet.

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Pregnancy

Caution

Twigan 20mg/500mg Tablet should be used during pregnancy only if potential benefit over weigh potential risk to fetus.

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Breast Feeding

Caution

Please seek medical advice if you are a breastfeeding mother before starting Twigan 20mg/500mg Tablet.

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Driving

Caution

Twigan 20mg/500mg Tablet may cause dizziness, drowsiness, and visual disturbances, which may affect their ability to drive or operate machinery. Make sure you are not affected before driving or operating machinery.

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Liver

Caution

Twigan 20mg/500mg Tablet to be taken with caution if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Twigan 20mg/500mg Tablet to be taken with caution if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Pediatric drops/oral liquid are not recommended in children unless prescribed by a doctor. The doctor will decide the dose and duration based on your child’s age and medical condition.

Country of origin

India

Manufacturer/Marketer address

601 Akik Complex, Near Pakwan Ii, Bodakdev, S G Highway, Ahmedabad, Gujarat, India - 380054
Other Info - TW54842

Author Details

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FAQs

Twigan 20mg/500mg Tablet is used in the treatment of spasmodic pain and discomfort due to biliary colic, intestinal colic, renal colic and spasmodic dysmenorrhea (painful, irregular periods). It also helps alleviate the symptoms of irritable bowel syndrome (IBS).Â
Twigan 20mg/500mg Tablet works by relaxing the muscles and inhibiting natural gut movements, thereby relieving muscle spasms and cramps in the stomach and intestine, abdominal pain, constipation and other GI discomforts.
Antacids may lower the absorption of Twigan 20mg/500mg Tablet and reduce its efficacy. It is advised to take antacid and Twigan 20mg/500mg Tablet at different times. If you take antacid after meals, please take Twigan 20mg/500mg Tablet before meals.
If you suffer from IBS, limit taking high fibre foods, foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods. Do not have large meals; instead, try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.
The use of Twigan 20mg/500mg Tablet can cause diarrhea in some cases. In the case of diarrhea, increase the intake of fluids like drink plenty of water. If still diarrhea persists, inform your doctor and do as advised.
Yes, the use of Twigan 20mg/500mg Tablet can cause dry mouth. If you feel excessively thirsty, increase fluid intake, and avoid spicy and salty food.
Limited research available. Please discuss with your doctor if you have any concerns regarding this.
Yes, alcohol consumption may increase symptoms of GERD and cause damage to the esophageal mucosa.
Smoking causes several common digestive system ailments, including heartburn and gastroesophageal reflux disease (GERD), peptic ulcers, and various liver diseases.
Twigan 20mg/500mg Tablet is usually safe to use in the dose as recommended by the doctor.
There are no known reported contraindications with Twigan 20mg/500mg Tablet when administered in recommended doses. However, Twigan 20mg/500mg Tablet is considered harmful for patients with known allergies to any of the components or excipients of this medicine.
It is best to take Twigan 20mg/500mg Tablet after meals. Swallow it as whole with water. Do not open, chew or crush it. Follow your doctor’s instructions carefully.
Twigan 20mg/500mg Tablet may cause a fast or irregular heartbeat or palpitations, which may worsen some symptoms of these conditions. Please seek medical attention if you face any issues.
Store in a cool and dry place away from sunlight. Keep Twigan 20mg/500mg Tablet out of the sight and reach of children.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.
Taking more than the recommended dosage does not provide additional relief and can increase the risk of adverse effects.

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