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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:40 PM IST
Tusslon-P Syrup Orange is used to treat the allergies and common cold symptoms like sneezing, runny/stuffy nose, watery eyes, and itchy nose/throat. It works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps in shrinking the blood vessels in the nasal passage, thereby reducing a stuffy nose. Also, it inhibits the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever. Some people may experience drowsiness, headache, tiredness, stomach upset, restlessness, and dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Tusslon-P Syrup Orange

Tusslon-P Syrup Orange is a cough and cold medication used to treat allergies and common cold symptoms like sneezing, runny/stuffy nose, watery eyes, and itchy nose/throat. The common cold is a respiratory illness affecting the nose and throat, mostly caused by viruses known as 'rhinovirus'. This virus attacks the body through the mouth, nose, or eyes and spreads easily through droplets in the air when a person who is sick sneezes, coughs, or talks.

Tusslon-P Syrup Orange is composed of three medicines, namely Levocetirizine (antihistamine/antiallergic), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing a stuffy nose. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

Take Tusslon-P Syrup Orange with or without food as prescribed by your doctor. Do not crush, chew, or break it. If Tusslon-P Syrup Orange is in syrup form, measure it with a measuring cup. Your doctor will recommend how often you take Tusslon-P Syrup Orange based on your medical condition. Some people may experience drowsiness, headache, tiredness, stomach upset, restlessness, and dry mouth. Most of these side effects of Tusslon-P Syrup Orange do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Tusslon-P Syrup Orange or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Tusslon-P Syrup Orange. It should be used with caution in children only if prescribed by a doctor. If you have high blood pressure, kidney or liver problems, coronary artery disease (heart problems), or are receiving any monoamine oxidase inhibitor (MAO) therapy to treat depression like Isocarboxazid, Phenelzine, Selegiline, Tranylcypromine etc., inform your doctor before taking Tusslon-P Syrup Orange. Do not drink alcohol with Tusslon-P Syrup Orange as it may potentiate the dizziness property of Cetrizine. Hence, it is advisable not to drive or operate heavy machinery or do hazardous work, which requires mental alertness. Taking more than 4 gm per day of paracetamol can damage your liver severely, so if you have liver problems, please contact your doctor.

Uses of Tusslon-P Syrup Orange

Treatment of Allergies, Common cold.

Medicinal Benefits

Tusslon-P Syrup Orange is primarily used to treat common cold symptoms and reduce symptoms of allergies. It is composed of three medicines, namely Levocetirizine (antihistamine), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps shrink the blood vessels in the nostrils and the passage and reduces stuffy noses. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

Directions for Use

Take this medicine as prescribed by your doctor. Take it with or without food and swallow it whole with a glass of water. Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tusslon-P Syrup Orange

  • Drowsiness
  • Headache
  • Tiredness
  • Stomach upset
  • Restlessness
  • Dry mouth

Drug Warnings

Do not take Tusslon-P Syrup Orange if you are allergic to Tusslon-P Syrup Orange or any of its ingredients, are pregnant or breastfeeding before starting Tusslon-P Syrup Orange. If you have high blood pressure,  kidney or liver disease, coronary artery disease, please do not take Tusslon-P Syrup Orange as it is known to interact. Also, inform your doctor about all other medications you have been taking before starting Tusslon-P Syrup Orange. Do not stop taking Tusslon-P Syrup Orange even if you feel better without asking your doctor as your symptoms may come back and may even worsen your condition. Tusslon-P Syrup Orange may cause drowsiness and sleepiness, so it is advised not to drive a car or operate machinery. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Tusslon-P Syrup Orange if you have taken any MAO inhibitor (anti-depressant medication) in the past 14 days.

Drug Interactions

Drug-Drug Interactions: Tusslon-P Syrup Orange may interact with blood thinners (warfarin, aspirin), antibiotics (chloramphenicol), high cholesterol-lowering medicines (cholestyramine), anti-sickness drugs (domperidone, metoclopramide), anti-allergic drugs (diphenhydramine), drugs used to reduce acid in the stomach (pantoprazole), anti-depressants (isocarboxazid, rasagiline, linezolid, tranylcypromine).

Drug-Food Interactions: Do not take St. John’s Wort (herbal supplement for depression) with Tusslon-P Syrup Orange.

Drug-Disease Interactions: If you have high blood pressure, kidney or liver problems, heart diseases like coronary artery disease, are receiving monoamine oxidase inhibitor (MAO) therapy (antidepressant medicines), inform your doctor before taking Tusslon-P Syrup Orange.

Drug-Drug Interactions Checker List

  • WARFARIN
  • ASPIRIN
  • CHLORAMPHENICOL
  • CHOLESTYRAMINE
  • DOMPERIDONE
  • METOCLOPRAMIDE
  • DIPHENHYDRAMINE
  • PANTOPRAZOLE
  • ISOCARBOXAZID
  • RASAGILINE
  • LINEZOLID
  • TRANYLCYPROMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.

  • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health. 
  • Drink plenty of fluids to avoid dehydration.
  • Gargle with salt water for relief from sore throat.
  • Avoid alcohol consumption with Tusslon-P Syrup Orange as it may cause tiredness, drowsiness, or lack of concentration.

Special Advise

  • Gargle with salt water for relief from sore throat.

  • Close liver monitoring is required especially if people with liver problems are using Tusslon-P Syrup Orange.

  • For people who have high blood pressure, if prescribed Tusslon-P Syrup Orange, you should regularly monitor your blood pressure.

Disease/Condition Glossary

Common cold: The common cold is an infection caused by viruses, mainly 'rhinovirus' affecting your nose and throat (upper respiratory tract). Children younger than 6 years of age are at the most significant risk of colds, but healthy adults can also be affected by having 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like dust, pollutants, etc. Symptoms of a common cold might include stuffy or runny nose, sore throat, cough, congestion, mild body pain or a mild headache, sneezing, low-grade fever, and feeling unwell (malaise). In some cases, the discharge from your nose may become thicker and yellow or green, which is not an indication of a bacterial infection.

Allergies: These occur when your body is attacked or invaded by allergy-causing agents known as 'allergens'. These allergens cause our body to release a chemical messenger called 'histamine, which causes inflammation, redness, itchiness, stuffy nose, watery eyes, etc. Allergies can caused by chemicals, air pollution, pet danders, pollens of plants, and seasonal allergies like hay fever.

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Alcohol

Unsafe

Avoid consumption of alcohol with Tusslon-P Syrup Orange as it may increase drowsiness. Please consult a doctor before consuming alcohol with Tusslon-P Syrup Orange.

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Pregnancy

Caution

The safety of Tusslon-P Syrup Orange in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

The safety of Tusslon-P Syrup Orange in breastfeeding mothers is unknown. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Tusslon-P Syrup Orange may cause drowsiness or tiredness in some people. Therefore, drive only if you are alert after taking Tusslon-P Syrup Orange.

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Liver

Caution

Take Tusslon-P Syrup Orange with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Tusslon-P Syrup Orange with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Tusslon-P Syrup Orange is not recommended for children below 12 years of age. However, please consult a doctor before giving Tusslon-P Syrup Orange to children.

Other Info - TUSS508

Author Details

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FAQs

Tusslon-P Syrup Orange is a cough and cold medication primarily used to treat allergies and common cold symptoms like sneezing, runny/stuffy nose, watery eyes, and itchy nose/throat.
Tusslon-P Syrup Orange is composed of three medicines, namely Levocetirizine (antihistamine), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nostrils and the passage and reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.
No, you are not recommended to stop taking Tusslon-P Syrup Orange without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Tusslon-P Syrup Orange for as long as your doctor has prescribed it, and if you experience any difficulty while taking Tusslon-P Syrup Orange, please consult your doctor.
No, you should not take Tusslon-P Syrup Orange along with high blood pressure (hypertension) medication, leading to a further rise in blood pressure. Please inform your doctor if you have high blood pressure before starting Tusslon-P Syrup Orange.
Yes, Cetirizine present in Tusslon-P Syrup Orange may cause drowsiness. It is not necessary for everyone taking Tusslon-P Syrup Orange to experience this side effect. Therefore, avoid driving and drinking alcohol if you feel drowsy after taking Tusslon-P Syrup Orange.
No, you are not recommended to consume alcohol with Tusslon-P Syrup Orange as it may increase drowsiness, dizziness, and lack of concentration.
No, you are not recommended to take Tusslon-P Syrup Orange with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness, or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.

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