Triptolol Tablet belongs to a group of medicines called tricyclic anti-depressants used to prevent migraine attacks with co-morbid conditions like insomnia, neuralgia pain, hypertension, and anxiety. A migraine is usually a moderate or severe headache felt as a throbbing pain on one side of the head.

Triptolol Tablet is a combination of two medicines, namely, amitriptyline and propranolol. Amitriptyline inhibits the membrane pump mechanism responsible for the serotonin uptake in serotonergic neurons, increasing serotonin levels and decreasing electrical activity in the brain. Amitriptyline can also change how your nerves receive pain signals so the pain goes away. Propranolol is a beta-blocker. It also widens the blood vessels in the body for better blood flow. Thereby, it helps to relieve your symptoms of pain or migraine.

You are advised to take Triptolol Tablet for as long as your doctor has prescribed it for you, depending on your medical condition and response to the treatment. In some cases, you may experience common side effects such as weight gain, dry mouth, blurred vision, increased intraocular pressure, constipation, sedation and drowsiness, hypotension, syncope, tachycardia, palpitations, myocardial infarction, and arrhythmias. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue using Triptolol Tablet for as long as your doctor has prescribed it. Do not use Triptolol Tablet without a doctor's advice if you had a skin reaction or irritation to any medicine. Consult your doctor before using Triptolol Tablet if you are pregnant or breastfeeding. Do not use Triptolol Tablet in more than prescribed doses or longer duration as it may cause adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Triptolol Tablet to rule out any side effects.

Triptolol Tablet prevents migraine attacks with co-morbid conditions like insomnia, neuralgic pain, hypertension, and anxiety. It contains amitriptyline and propranolol. Amitriptyline inhibits the membrane pump mechanism responsible for the serotonin uptake in serotonergic neurons, increasing serotonin levels and decreasing electrical activity in the brain. Amitriptyline can also change how your nerves receive pain signals so the pain goes away. Propranolol is a beta-blocker. It also widens the blood vessels in the body for better blood flow. Thereby, it helps to relieve your symptoms of pain or migraine.

• Weight gain
• Dry mouth
• Blurred vision
• Increased intraocular pressure
• Constipation
• Drowsiness
• Hypotension

To treat your condition effectually, continue taking Triptolol Tablet for as long as your doctor has prescribed. Do not take Triptolol Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Triptolol Tablet causes drowsiness, sleepiness and dizziness, do not drive unless you are alert. Avoid consuming alcohol along with Triptolol Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects. Triptolol Tablet can cause extra side effects if you stop taking it suddenly. Talk to your doctor if you want to stop taking it. Amitriptyline in Triptolol Tablet may cause decreased sex drive and problems with erections and orgasm. Also, Amitriptyline can change appetite.

Drug-Drug Interactions: Triptolol Tablet may interact with a medication used to help people with alcoholism avoid drinking (e.g. disulfiram), blood thinner medication (e.g. warfarin), a heartburn/ulcer medication (e.g. cimetidine), medicines used to treat high blood pressure (e.g. clonidine, labetalol), a drug used to treat HIV infection (e.g. delavirdine), a diarrhoea medication (e.g. diphenoxylate), medicines used in chemotherapy (e.g. imatinib and procarbazine), hormonal medicines (e.g. levothyroxine), a medicine used to treat anxiety disorders and panic disorder (e.g. alprazolam), medications used to treat certain types of seizures (e.g. pregabalin), skeletal muscle relaxant medications (e.g. cyclobenzaprine), a medicine used to treat epilepsy (e.g. topiramate) and medicines used to treat depression (e.g. duloxetine, escitalopram, topiramate).

Drug-Food Interactions: Avoid consuming alcohol along with Triptolol Tablet as it may increase the sedative effects.

Drug-Disease Interactions: Triptolol Tablet may interact with disease conditions, including anticholinergic effects, cardiovascular disease, pheochromocytoma, acute myocardial infarction recovery, cardiovascular disease, depression, seizure disorders, bradyarrhythmia/AV block, cardiogenic shock/hypotension, CHF (Congestive Heart Failure), diabetes, hypersensitivity, ischemic heart disease, PVD (Peripheral Arterial Disease), asthma and liver disease.

• DISULFIRAM
• WARFARIN
• CIMETIDINE
• CLONIDINE
• LABETALOL
• DELAVIRDINE
• DIPHENOXYLATE
• IMATINIB
• PROCARBAZINE
• LEVOTHYROXINE
• ALPRAZOLAM
• PREGABALIN
• CYCLOBENZAPRINE
• TOPIRAMATE
• DULOXETINE
• ESCITALOPRAM

• Maintaining a healthy diet and exercising regularly helps improve overall health and boosts self-esteem.
• Regularly attend therapy sessions.
• Perform meditation and yoga. This helps in relieving stress and provides relaxation.
• Follow a regular sleep pattern to improve the amount and quality of sleep you get.
• Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables and olive oils.
• Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help maintain neurotransmitters.
• Complex carbohydrates help in stimulating serotonin (a feel-good neurotransmitter). These include whole grains, legumes, spinach, broccoli, oranges and pears.
• Exercising helps in the production of the body’s natural antidepressants. It also helps relieve stress, improve mood, boost self-esteem, and provide restful sleep.
• Avoid smoking and alcohol consumption.
• Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Migraine: A migraine is a headache that is usually moderate or severe, with throbbing pain on one side of the brain. Migraine is a frequent health problem that affects one out of every five women and one out of every fifteen males. They usually start while a person is in their early twenties. Many people also experience symptoms like nausea, vomiting, and increased sensitivity to light and sound.

Insomnia: It is a condition in which you have difficulty sleeping on a regular basis. It normally improves with a change in sleeping patterns. Short-term insomnia is defined as insomnia that lasts for less than three months. Long-term insomnia is defined as insomnia that lasts three months or more. Stress, anxiety, or sadness, noise, alcohol, coffee, or nicotine, uncomfortable beds, a room that is too hot or chilly, and using recreational drugs such as cocaine or ecstasy are all typical causes of insomnia.

Neuralgic Pain: It is defined as pain caused by injured or inflamed nerves. Shingles, trigeminal neuralgia, and diabetes are all conditions linked to Neuralgic Pain or Neuralgia. Numbness, tingling, or other unpleasant sensations along the nerve's route are sometimes experienced in addition to pain.